250 related articles for article (PubMed ID: 2870801)
1. Covalent binding of 1,2-dihaloalkanes to DNA and stability of the major DNA adduct, S-[2-(N7-guanyl)ethyl]glutathione.
Inskeep PB; Koga N; Cmarik JL; Guengerich FP
Cancer Res; 1986 Jun; 46(6):2839-44. PubMed ID: 2870801
[TBL] [Abstract][Full Text] [Related]
2. Selectivity of rat and human glutathione S-transferases in activation of ethylene dibromide by glutathione conjugation and DNA binding and induction of unscheduled DNA synthesis in human hepatocytes.
Cmarik JL; Inskeep PB; Meredith MJ; Meyer DJ; Ketterer B; Guengerich FP
Cancer Res; 1990 May; 50(9):2747-52. PubMed ID: 2328501
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of oligonucleotides containing the ethylene dibromide-derived DNA adducts S-[2-(N7-guanyl)ethyl]glutathione, S-[2-(N2-guanyl)ethyl]glutathione, and S-[2-(O6-guanyl)ethyl]glutathione at a single site.
Kim MS; Guengerich FP
Chem Res Toxicol; 1997 Oct; 10(10):1133-43. PubMed ID: 9348436
[TBL] [Abstract][Full Text] [Related]
4. Excretion of the mercapturic acid S-[2-(N7-guanyl)ethyl]-N-acetylcysteine in urine following administration of ethylene dibromide to rats.
Kim DH; Guengerich FP
Cancer Res; 1989 Nov; 49(21):5843-7. PubMed ID: 2790795
[TBL] [Abstract][Full Text] [Related]
5. Polymerase blockage and misincorporation of dNTPs opposite the ethylene dibromide-derived DNA adducts S-[2-(N7-guanyl)ethyl]glutathione, S-[2-(N2-guanyl)ethyl]glutathione, and S-[2-(O6-guanyl)ethyl]glutathione.
Kim MS; Guengerich FP
Chem Res Toxicol; 1998 Apr; 11(4):311-6. PubMed ID: 9548801
[TBL] [Abstract][Full Text] [Related]
6. Activation of dihaloalkanes by glutathione conjugation and formation of DNA adducts.
Guengerich FP; Peterson LA; Cmarik JL; Koga N; Inskeep PB
Environ Health Perspect; 1987 Dec; 76():15-8. PubMed ID: 3329096
[TBL] [Abstract][Full Text] [Related]
7. DNA-glutathione adducts derived from vic-dihaloalkanes: mechanisms of mutagenesis.
Guengerich FP; Humphreys WG; Kim DH; Oida T; Cmarik JL
Princess Takamatsu Symp; 1990; 21():101-7. PubMed ID: 2134669
[TBL] [Abstract][Full Text] [Related]
8. Formation of the DNA adduct S-[2-(N7-guanyl)ethyl]glutathione from ethylene dibromide: effects of modulation of glutathione and glutathione S-transferase levels and lack of a role for sulfation.
Kim DH; Guengerich FP
Carcinogenesis; 1990 Mar; 11(3):419-24. PubMed ID: 2311185
[TBL] [Abstract][Full Text] [Related]
9. S-[2-(N7-guanyl)ethyl]glutathione, the major DNA adduct formed from 1,2-dibromoethane.
Koga N; Inskeep PB; Harris TM; Guengerich FP
Biochemistry; 1986 Apr; 25(8):2192-8. PubMed ID: 3707941
[TBL] [Abstract][Full Text] [Related]
10. Evidence for formation of an S-[2-(N7-guanyl)ethyl]glutathione adduct in glutathione-mediated binding of the carcinogen 1,2-dibromoethane to DNA.
Ozawa N; Guengerich FP
Proc Natl Acad Sci U S A; 1983 Sep; 80(17):5266-70. PubMed ID: 6577422
[TBL] [Abstract][Full Text] [Related]
11. Analysis of DNA adducts formed in vivo in rats and mice from 1,2-dibromoethane, 1,2-dichloroethane, dibromomethane, and dichloromethane using HPLC/accelerator mass spectrometry and relevance to risk estimates.
Watanabe K; Liberman RG; Skipper PL; Tannenbaum SR; Guengerich FP
Chem Res Toxicol; 2007 Nov; 20(11):1594-600. PubMed ID: 17907789
[TBL] [Abstract][Full Text] [Related]
12. Analysis of DNA adduct, S-[2-(N7-guanyl)ethyl]glutathione, by liquid chromatography/mass spectrometry and liquid chromatography/tandem mass spectrometry.
Huang H; Jemal A; David C; Barker SA; Swenson DH; Means JC
Anal Biochem; 1998 Dec; 265(1):139-50. PubMed ID: 9866718
[TBL] [Abstract][Full Text] [Related]
13. Characterization of S-[2-(N1-adenyl)ethyl]glutathione as an adduct formed in RNA and DNA from 1,2-dibromoethane.
Kim DH; Humphreys WG; Guengerich FP
Chem Res Toxicol; 1990; 3(6):587-94. PubMed ID: 1715767
[TBL] [Abstract][Full Text] [Related]
14. Mutation spectrum and sequence alkylation selectivity resulting from modification of bacteriophage M13mp18 DNA with S-(2-chloroethyl)glutathione. Evidence for a role of S-(2-N7-guanyl)ethyl)glutathione as a mutagenic lesion formed from ethylene dibromide.
Cmarik JL; Humphreys WG; Bruner KL; Lloyd RS; Tibbetts C; Guengerich FP
J Biol Chem; 1992 Apr; 267(10):6672-9. PubMed ID: 1551876
[TBL] [Abstract][Full Text] [Related]
15. In vitro biotransformation and genotoxicity of the drinking water disinfection byproduct bromodichloromethane: DNA binding mediated by glutathione transferase theta 1-1.
Ross MK; Pegram RA
Toxicol Appl Pharmacol; 2004 Mar; 195(2):166-81. PubMed ID: 14998683
[TBL] [Abstract][Full Text] [Related]
16. In vitro metabolism of 1,2-dihaloethanes to ethylene.
Livesey JC; Anders MW
Drug Metab Dispos; 1979; 7(4):199-203. PubMed ID: 39719
[TBL] [Abstract][Full Text] [Related]
17. Binding of carcinogenic halogenated hydrocarbons to cell macromolecules.
Banerjee S; Van Duuren BL
J Natl Cancer Inst; 1979 Sep; 63(3):707-11. PubMed ID: 381753
[TBL] [Abstract][Full Text] [Related]
18. Isolation and characterization of N7-guanyl adducts derived from 1,2-dibromo-3-chloropropane.
Humphreys WG; Kim DH; Guengerich FP
Chem Res Toxicol; 1991; 4(4):445-53. PubMed ID: 1912332
[TBL] [Abstract][Full Text] [Related]
19. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
Beland FA
Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
[TBL] [Abstract][Full Text] [Related]
20. Glutathione-mediated binding of dibromoalkanes to DNA: specificity of rat glutathione-S-transferases and dibromoalkane structure.
Inskeep PB; Guengerich FP
Carcinogenesis; 1984 Jun; 5(6):805-8. PubMed ID: 6373044
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
