223 related articles for article (PubMed ID: 28714573)
1. Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation.
Witt KL; Hsieh JH; Smith-Roe SL; Xia M; Huang R; Zhao J; Auerbach SS; Hur J; Tice RR
Environ Mol Mutagen; 2017 Aug; 58(7):494-507. PubMed ID: 28714573
[TBL] [Abstract][Full Text] [Related]
2. Evaluation of high-throughput genotoxicity assays used in profiling the US EPA ToxCast chemicals.
Knight AW; Little S; Houck K; Dix D; Judson R; Richard A; McCarroll N; Akerman G; Yang C; Birrell L; Walmsley RM
Regul Toxicol Pharmacol; 2009 Nov; 55(2):188-99. PubMed ID: 19591892
[TBL] [Abstract][Full Text] [Related]
3. 3Rs-friendly approach to exogenous metabolic activation that supports high-throughput genetic toxicology testing.
Tian S; Cyr A; Zeise K; Bryce SM; Hall N; Bemis JC; Dertinger SD
Environ Mol Mutagen; 2020 Apr; 61(4):408-432. PubMed ID: 32039521
[TBL] [Abstract][Full Text] [Related]
4. Identifying Compounds with Genotoxicity Potential Using Tox21 High-Throughput Screening Assays.
Hsieh JH; Smith-Roe SL; Huang R; Sedykh A; Shockley KR; Auerbach SS; Merrick BA; Xia M; Tice RR; Witt KL
Chem Res Toxicol; 2019 Jul; 32(7):1384-1401. PubMed ID: 31243984
[TBL] [Abstract][Full Text] [Related]
5. Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage.
Clewell RA; Sun B; Adeleye Y; Carmichael P; Efremenko A; McMullen PD; Pendse S; Trask OJ; White A; Andersen ME
Toxicol Sci; 2014 Nov; 142(1):56-73. PubMed ID: 25078064
[TBL] [Abstract][Full Text] [Related]
6. γH2AX and p53 responses in TK6 cells discriminate promutagens and nongenotoxicants in the presence of rat liver S9.
Bernacki DT; Bryce SM; Bemis JC; Kirkland D; Dertinger SD
Environ Mol Mutagen; 2016 Aug; 57(7):546-558. PubMed ID: 27364561
[TBL] [Abstract][Full Text] [Related]
7. The TGx-28.65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures.
Jackson MA; Yang L; Lea I; Rashid A; Kuo B; Williams A; Lyn Yauk C; Fostel J
Environ Mol Mutagen; 2017 Aug; 58(7):529-535. PubMed ID: 28766826
[TBL] [Abstract][Full Text] [Related]
8. An evaluation of 25 selected ToxCast chemicals in medium-throughput assays to detect genotoxicity.
Kligerman AD; Young RR; Stankowski LF; Pant K; Lawlor T; Aardema MJ; Houck KA
Environ Mol Mutagen; 2015 Jun; 56(5):468-76. PubMed ID: 25537651
[TBL] [Abstract][Full Text] [Related]
9. Development of a panel of high-throughput reporter-gene assays to detect genotoxicity and oxidative stress.
van der Linden SC; von Bergh AR; van Vught-Lussenburg BM; Jonker LR; Teunis M; Krul CA; van der Burg B
Mutat Res Genet Toxicol Environ Mutagen; 2014 Jan; 760():23-32. PubMed ID: 24362253
[TBL] [Abstract][Full Text] [Related]
10. Identification of genotoxic compounds using isogenic DNA repair deficient DT40 cell lines on a quantitative high throughput screening platform.
Nishihara K; Huang R; Zhao J; Shahane SA; Witt KL; Smith-Roe SL; Tice RR; Takeda S; Xia M
Mutagenesis; 2016 Jan; 31(1):69-81. PubMed ID: 26243743
[TBL] [Abstract][Full Text] [Related]
11. A Quantitative Toxicogenomics Assay for High-throughput and Mechanistic Genotoxicity Assessment and Screening of Environmental Pollutants.
Lan J; Gou N; Rahman SM; Gao C; He M; Gu AZ
Environ Sci Technol; 2016 Mar; 50(6):3202-14. PubMed ID: 26855253
[TBL] [Abstract][Full Text] [Related]
12. Direct quantification of gamma H2AX by cell-based high throughput screening for evaluation of genotoxicity of pesticides in a human thyroid cell lines.
Hershman JM; France B; Hon K; Damoiseaux R
Environ Mol Mutagen; 2017 Aug; 58(7):522-528. PubMed ID: 28640454
[TBL] [Abstract][Full Text] [Related]
13. Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay.
Bryce SM; Bernacki DT; Bemis JC; Spellman RA; Engel ME; Schuler M; Lorge E; Heikkinen PT; Hemmann U; Thybaud V; Wilde S; Queisser N; Sutter A; Zeller A; Guérard M; Kirkland D; Dertinger SD
Environ Mol Mutagen; 2017 Apr; 58(3):146-161. PubMed ID: 28370322
[TBL] [Abstract][Full Text] [Related]
14. A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants.
Ji K; Kogame T; Choi K; Wang X; Lee J; Taniguchi Y; Takeda S
Environ Health Perspect; 2009 Nov; 117(11):1737-44. PubMed ID: 20049126
[TBL] [Abstract][Full Text] [Related]
15. Contribution of ATM and ATR kinase pathways to p53-mediated response in etoposide and methyl methanesulfonate induced DNA damage.
Sun B; Ross SM; Rowley S; Adeleye Y; Clewell RA
Environ Mol Mutagen; 2017 Mar; 58(2):72-83. PubMed ID: 28195382
[TBL] [Abstract][Full Text] [Related]
16. Validation of a human cell based high-throughput genotoxicity assay 'Anthem's Genotoxicity screen' using ECVAM recommended lists of genotoxic and non-genotoxic chemicals.
Rajakrishna L; Krishnan Unni S; Subbiah M; Sadagopan S; Nair AR; Chandrappa R; Sambasivam G; Sukumaran SK
Toxicol In Vitro; 2014 Feb; 28(1):46-53. PubMed ID: 23850743
[TBL] [Abstract][Full Text] [Related]
17. Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation.
Ooka M; Zhao J; Shah P; Travers J; Klumpp-Thomas C; Xu X; Huang R; Ferguson S; Witt KL; Smith-Roe SL; Simeonov A; Xia M
Arch Toxicol; 2022 Jul; 96(7):1975-1987. PubMed ID: 35435491
[TBL] [Abstract][Full Text] [Related]
18. Performance of the in vitro transgene mutation assay in MutaMouse FE1 cells: Evaluation of nine misleading ("False") positive chemicals.
Maertens RM; Long AS; White PA
Environ Mol Mutagen; 2017 Oct; 58(8):582-591. PubMed ID: 28843037
[TBL] [Abstract][Full Text] [Related]
19. Activation of P53 in HepG2 cells as surrogate to detect mutagens and promutagens in vitro.
Boehme K; Dietz Y; Hewitt P; Mueller SO
Toxicol Lett; 2010 Oct; 198(2):272-81. PubMed ID: 20655369
[TBL] [Abstract][Full Text] [Related]
20. Development of a cellular biosensor system for genotoxicity detection based on Trp53 promoter.
Siqian L; Lei S; Ying L
Hum Exp Toxicol; 2016 Oct; 35(10):1102-7. PubMed ID: 26721909
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
