BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 28714573)

  • 21. Investigating the Generalizability of the MultiFlow ® DNA Damage Assay and Several Companion Machine Learning Models With a Set of 103 Diverse Test Chemicals.
    Bryce SM; Bernacki DT; Smith-Roe SL; Witt KL; Bemis JC; Dertinger SD
    Toxicol Sci; 2018 Mar; 162(1):146-166. PubMed ID: 29106658
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Genotoxicity of environmental agents assessed by the alkaline comet assay.
    Møller P
    Basic Clin Pharmacol Toxicol; 2005; 96 Suppl 1():1-42. PubMed ID: 15859009
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Implementation of a 220,000-compound HCS campaign to identify disruptors of the interaction between p53 and hDM2 and characterization of the confirmed hits.
    Dudgeon DD; Shinde S; Hua Y; Shun TY; Lazo JS; Strock CJ; Giuliano KA; Taylor DL; Johnston PA; Johnston PA
    J Biomol Screen; 2010 Aug; 15(7):766-82. PubMed ID: 20639499
    [TBL] [Abstract][Full Text] [Related]  

  • 24. p53 induction and cell viability modulation by genotoxic individual chemicals and mixtures.
    Di Paolo C; Müller Y; Thalmann B; Hollert H; Seiler TB
    Environ Sci Pollut Res Int; 2018 Feb; 25(5):4012-4022. PubMed ID: 28303539
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Benchmark Dose Analysis of DNA Damage Biomarker Responses Provides Compound Potency and Adverse Outcome Pathway Information for the Topoisomerase II Inhibitor Class of Compounds.
    Wheeldon RP; Bernacki DT; Dertinger SD; Bryce SM; Bemis JC; Johnson GE
    Environ Mol Mutagen; 2020 Apr; 61(4):396-407. PubMed ID: 31983063
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A new genotoxicity assay based on p53 target gene induction.
    Zerdoumi Y; Kasper E; Soubigou F; Adriouch S; Bougeard G; Frebourg T; Flaman JM
    Mutat Res Genet Toxicol Environ Mutagen; 2015 Aug; 789-790():28-35. PubMed ID: 26232255
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The development and prevalidation of an in vitro mutagenicity assay based on MutaMouse primary hepatocytes, Part II: Assay performance for the identification of mutagenic chemicals.
    Cox JA; Zwart EP; Luijten M; White PA
    Environ Mol Mutagen; 2019 May; 60(4):348-360. PubMed ID: 30714215
    [TBL] [Abstract][Full Text] [Related]  

  • 28. BPDE-induced genotoxicity: relationship between DNA adducts, mutagenicity in the in vitro PIG-A assay, and the transcriptional response to DNA damage in TK6 cells.
    Piberger AL; Krüger CT; Strauch BM; Schneider B; Hartwig A
    Arch Toxicol; 2018 Jan; 92(1):541-551. PubMed ID: 28593498
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development.
    Westerink WM; Stevenson JC; Horbach GJ; Schoonen WG
    Mutat Res; 2010 Feb; 696(1):21-40. PubMed ID: 20006733
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Predictions of genotoxic potential, mode of action, molecular targets, and potency via a tiered multiflow® assay data analysis strategy.
    Dertinger SD; Kraynak AR; Wheeldon RP; Bernacki DT; Bryce SM; Hall N; Bemis JC; Galloway SM; Escobar PA; Johnson GE
    Environ Mol Mutagen; 2019 Jul; 60(6):513-533. PubMed ID: 30702769
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Yeast-based genotoxicity tests for assessing DNA alterations and DNA stress responses: a 40-year overview.
    Eki T
    Appl Microbiol Biotechnol; 2018 Mar; 102(6):2493-2507. PubMed ID: 29423630
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Towards an advanced testing strategy for genotoxicity using image-based 2D and 3D HepG2 DNA damage response fluorescent protein reporters.
    Ter Braak B; Niemeijer M; Wolters L; Le Dévédec S; Bouwman P; van de Water B
    Mutagenesis; 2022 May; 37(2):130-142. PubMed ID: 34448005
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Genotoxicity: damage to DNA and its consequences.
    Phillips DH; Arlt VM
    EXS; 2009; 99():87-110. PubMed ID: 19157059
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Classification of in vitro genotoxicants using a novel multiplexed biomarker assay compared to the flow cytometric micronucleus test.
    Wilde S; Dambowsky M; Hempt C; Sutter A; Queisser N
    Environ Mol Mutagen; 2017 Dec; 58(9):662-677. PubMed ID: 28940655
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Evaluation of the LacZ reporter assay in cryopreserved primary hepatocytes for In vitro genotoxicity testing.
    Luijten M; Zwart EP; Dollé ME; de Pooter M; Cox JA; White PA; van Benthem J
    Environ Mol Mutagen; 2016 Dec; 57(9):643-655. PubMed ID: 27859631
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts.
    Wang W; Kim SH; El-Deiry WS
    Proc Natl Acad Sci U S A; 2006 Jul; 103(29):11003-8. PubMed ID: 16835297
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The development and validation of EpiComet-Chip, a modified high-throughput comet assay for the assessment of DNA methylation status.
    Townsend TA; Parrish MC; Engelward BP; Manjanatha MG
    Environ Mol Mutagen; 2017 Aug; 58(7):508-521. PubMed ID: 28755435
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Emerging metrology for high-throughput nanomaterial genotoxicology.
    Nelson BC; Wright CW; Ibuki Y; Moreno-Villanueva M; Karlsson HL; Hendriks G; Sims CM; Singh N; Doak SH
    Mutagenesis; 2017 Jan; 32(1):215-232. PubMed ID: 27565834
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Analysis of positions and substituents on genotoxicity of fluoroquinolones with quantitative structure-activity relationship and 3D Pharmacophore model.
    Fengxian C; Reti H
    Ecotoxicol Environ Saf; 2017 Feb; 136():111-118. PubMed ID: 27835744
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Sensitive DsRed fluorescence-based reporter cell systems for genotoxicity and oxidative stress assessment.
    Hendriks G; Atallah M; Raamsman M; Morolli B; van der Putten H; Jaadar H; Tijdens I; Esveldt-van Lange R; Mullenders L; van de Water B; Vrieling H
    Mutat Res; 2011 May; 709-710():49-59. PubMed ID: 21382384
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.