BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 28716551)

  • 1. Application of human induced pluripotent stem cells to model fibrodysplasia ossificans progressiva.
    Barruet E; Hsiao EC
    Bone; 2018 Apr; 109():162-167. PubMed ID: 28716551
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling.
    Barruet E; Morales BM; Lwin W; White MP; Theodoris CV; Kim H; Urrutia A; Wong SA; Srivastava D; Hsiao EC
    Stem Cell Res Ther; 2016 Aug; 7(1):115. PubMed ID: 27530160
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An mTOR Signaling Modulator Suppressed Heterotopic Ossification of Fibrodysplasia Ossificans Progressiva.
    Hino K; Zhao C; Horigome K; Nishio M; Okanishi Y; Nagata S; Komura S; Yamada Y; Toguchida J; Ohta A; Ikeya M
    Stem Cell Reports; 2018 Nov; 11(5):1106-1119. PubMed ID: 30392977
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The obligatory role of Activin A in the formation of heterotopic bone in Fibrodysplasia Ossificans Progressiva.
    Alessi Wolken DM; Idone V; Hatsell SJ; Yu PB; Economides AN
    Bone; 2018 Apr; 109():210-217. PubMed ID: 28629737
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva.
    Cai J; Orlova VV; Cai X; Eekhoff EMW; Zhang K; Pei D; Pan G; Mummery CL; Ten Dijke P
    Stem Cell Reports; 2015 Dec; 5(6):963-970. PubMed ID: 26626181
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Depletion of Mast Cells and Macrophages Impairs Heterotopic Ossification in an Acvr1
    Convente MR; Chakkalakal SA; Yang E; Caron RJ; Zhang D; Kambayashi T; Kaplan FS; Shore EM
    J Bone Miner Res; 2018 Feb; 33(2):269-282. PubMed ID: 28986986
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neofunction of ACVR1 in fibrodysplasia ossificans progressiva.
    Hino K; Ikeya M; Horigome K; Matsumoto Y; Ebise H; Nishio M; Sekiguchi K; Shibata M; Nagata S; Matsuda S; Toguchida J
    Proc Natl Acad Sci U S A; 2015 Dec; 112(50):15438-43. PubMed ID: 26621707
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice With the Human ACVR1(R206H) Fibrodysplasia Ossificans Progressiva (FOP) Mutation.
    Chakkalakal SA; Uchibe K; Convente MR; Zhang D; Economides AN; Kaplan FS; Pacifici M; Iwamoto M; Shore EM
    J Bone Miner Res; 2016 Sep; 31(9):1666-75. PubMed ID: 26896819
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activin A amplifies dysregulated BMP signaling and induces chondro-osseous differentiation of primary connective tissue progenitor cells in patients with fibrodysplasia ossificans progressiva (FOP).
    Wang H; Shore EM; Pignolo RJ; Kaplan FS
    Bone; 2018 Apr; 109():218-224. PubMed ID: 29170109
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hints on transcriptional control of essential players in heterotopic ossification of Fibrodysplasia Ossificans Progressiva.
    Ravazzolo R; Cappato S; Bocciardi R
    Bone; 2018 Apr; 109():187-191. PubMed ID: 29100956
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of altered signal transduction in heterotopic ossification and fibrodysplasia ossificans progressiva.
    Shore EM; Kaplan FS
    Curr Osteoporos Rep; 2011 Jun; 9(2):83-8. PubMed ID: 21340697
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modeling the
    Barruet E; Garcia SM; Wu J; Morales BM; Tamaki S; Moody T; Pomerantz JH; Hsiao EC
    Elife; 2021 Nov; 10():. PubMed ID: 34755602
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1.
    Aykul S; Huang L; Wang L; Das NM; Reisman S; Ray Y; Zhang Q; Rothman N; Nannuru KC; Kamat V; Brydges S; Troncone L; Johnsen L; Yu PB; Fazio S; Lees-Shepard J; Schutz K; Murphy AJ; Economides AN; Idone V; Hatsell SJ
    J Clin Invest; 2022 Jun; 132(12):. PubMed ID: 35511419
    [TBL] [Abstract][Full Text] [Related]  

  • 14. iMSC-mediated delivery of ACVR2B-Fc fusion protein reduces heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva.
    Gao P; Inada Y; Hotta A; Sakurai H; Ikeya M
    Stem Cell Res Ther; 2024 Mar; 15(1):83. PubMed ID: 38500216
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A new era for fibrodysplasia ossificans progressiva: a druggable target for the second skeleton.
    Kaplan FS; Glaser DL; Pignolo RJ; Shore EM
    Expert Opin Biol Ther; 2007 May; 7(5):705-12. PubMed ID: 17477807
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs.
    Maekawa H; Jin Y; Nishio M; Kawai S; Nagata S; Kamakura T; Yoshitomi H; Niwa A; Saito MK; Matsuda S; Toguchida J
    Orphanet J Rare Dis; 2022 Sep; 17(1):364. PubMed ID: 36131296
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva.
    Hino K; Horigome K; Nishio M; Komura S; Nagata S; Zhao C; Jin Y; Kawakami K; Yamada Y; Ohta A; Toguchida J; Ikeya M
    J Clin Invest; 2017 Sep; 127(9):3339-3352. PubMed ID: 28758906
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Heterotopic Ossification in Mouse Models of Fibrodysplasia Ossificans Progressiva.
    Chakkalakal SA; Shore EM
    Methods Mol Biol; 2019; 1891():247-255. PubMed ID: 30414138
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cellular Hypoxia Promotes Heterotopic Ossification by Amplifying BMP Signaling.
    Wang H; Lindborg C; Lounev V; Kim JH; McCarrick-Walmsley R; Xu M; Mangiavini L; Groppe JC; Shore EM; Schipani E; Kaplan FS; Pignolo RJ
    J Bone Miner Res; 2016 Sep; 31(9):1652-65. PubMed ID: 27027798
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ACVR1
    Matsuo K; Lepinski A; Chavez RD; Barruet E; Pereira A; Moody TA; Ton AN; Sharma A; Hellman J; Tomoda K; Nakamura MC; Hsiao EC
    Bone; 2021 Dec; 153():116129. PubMed ID: 34311122
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.