These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 28719185)

  • 1. Small Molecule Enhancement of 20S Proteasome Activity Targets Intrinsically Disordered Proteins.
    Jones CL; Njomen E; Sjögren B; Dexheimer TS; Tepe JJ
    ACS Chem Biol; 2017 Sep; 12(9):2240-2247. PubMed ID: 28719185
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Small Molecule Modulation of Proteasome Assembly.
    Njomen E; Osmulski PA; Jones CL; Gaczynska M; Tepe JJ
    Biochemistry; 2018 Jul; 57(28):4214-4224. PubMed ID: 29897236
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dihydroquinazolines enhance 20S proteasome activity and induce degradation of α-synuclein, an intrinsically disordered protein associated with neurodegeneration.
    Fiolek TJ; Magyar CL; Wall TJ; Davies SB; Campbell MV; Savich CJ; Tepe JJ; Mosey RA
    Bioorg Med Chem Lett; 2021 Mar; 36():127821. PubMed ID: 33513387
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Syrosingopine Enhances 20S Proteasome Activity and Degradation of α-Synuclein.
    Sadahiro Y; Nishimura S; Hitora Y; Tsukamoto S
    J Nat Prod; 2024 Mar; 87(3):554-559. PubMed ID: 37938154
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fluspirilene Analogs Activate the 20S Proteasome and Overcome Proteasome Impairment by Intrinsically Disordered Protein Oligomers.
    Fiolek TJ; Keel KL; Tepe JJ
    ACS Chem Neurosci; 2021 Apr; 12(8):1438-1448. PubMed ID: 33788542
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Fragment-Based Method of Creating Small-Molecule Libraries to Target the Aggregation of Intrinsically Disordered Proteins.
    Joshi P; Chia S; Habchi J; Knowles TP; Dobson CM; Vendruscolo M
    ACS Comb Sci; 2016 Mar; 18(3):144-53. PubMed ID: 26923286
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Disordered Landscape of the 20S Proteasome Substrates Reveals Tight Association with Phase Separated Granules.
    Myers N; Olender T; Savidor A; Levin Y; Reuven N; Shaul Y
    Proteomics; 2018 Nov; 18(21-22):e1800076. PubMed ID: 30039638
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, Synthesis, and Biological Evaluation of Potent 20S Proteasome Activators for the Potential Treatment of α-Synucleinopathies.
    Staerz SD; Jones CL; Tepe JJ
    J Med Chem; 2022 May; 65(9):6631-6642. PubMed ID: 35476454
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rpt5-Derived Analogs Stimulate Human Proteasome Activity in Cells and Degrade Proteins Forming Toxic Aggregates in Age-Related Diseases.
    Cekała K; Trepczyk K; Witkowska J; Jankowska E; Wieczerzak E
    Int J Mol Sci; 2024 Apr; 25(9):. PubMed ID: 38731881
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism of cleavage of alpha-synuclein by the 20S proteasome and modulation of its degradation by the RedOx state of the N-terminal methionines.
    Alvarez-Castelao B; Goethals M; Vandekerckhove J; Castaño JG
    Biochim Biophys Acta; 2014 Feb; 1843(2):352-65. PubMed ID: 24315858
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Advances in Proteasome Enhancement by Small Molecules.
    George DE; Tepe JJ
    Biomolecules; 2021 Nov; 11(12):. PubMed ID: 34944433
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AM404 Analogs as Activators of the 20S Isoform of the Human Proteasome.
    Salazar-Chaparro A; Kragness K; Feleciano D; Trader DJ
    Chembiochem; 2024 Jun; 25(12):e202400284. PubMed ID: 38609329
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proteasome Activation to Combat Proteotoxicity.
    Jones CL; Tepe JJ
    Molecules; 2019 Aug; 24(15):. PubMed ID: 31387243
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of a Cell-Based AlphaLISA Assay for High-Throughput Screening for Small Molecule Proteasome Modulators.
    Staerz SD; Lisabeth EM; Njomen E; Dexheimer TS; Neubig RR; Tepe JJ
    ACS Omega; 2023 May; 8(17):15650-15659. PubMed ID: 37151549
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural Insights into Substrate Recognition and Processing by the 20S Proteasome.
    Sahu I; Glickman MH
    Biomolecules; 2021 Jan; 11(2):. PubMed ID: 33498876
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of the 20S Proteasome by a Novel Family of Inhibitory Proteins.
    Olshina MA; Arkind G; Kumar Deshmukh F; Fainer I; Taranavsky M; Hayat D; Ben-Dor S; Ben-Nissan G; Sharon M
    Antioxid Redox Signal; 2020 Mar; 32(9):636-655. PubMed ID: 31903784
    [No Abstract]   [Full Text] [Related]  

  • 17. The Parkinson's-associated protein DJ-1 regulates the 20S proteasome.
    Moscovitz O; Ben-Nissan G; Fainer I; Pollack D; Mizrachi L; Sharon M
    Nat Commun; 2015 Apr; 6():6609. PubMed ID: 25833141
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The molecular chaperone Hsp70 promotes the proteolytic removal of oxidatively damaged proteins by the proteasome.
    Reeg S; Jung T; Castro JP; Davies KJA; Henze A; Grune T
    Free Radic Biol Med; 2016 Oct; 99():153-166. PubMed ID: 27498116
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PA28γ-20S proteasome is a proteolytic complex committed to degrade unfolded proteins.
    Frayssinhes JA; Cerruti F; Laulin J; Cattaneo A; Bachi A; Apcher S; Coux O; Cascio P
    Cell Mol Life Sci; 2021 Dec; 79(1):45. PubMed ID: 34913092
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The C-Terminus of the PSMA3 Proteasome Subunit Preferentially Traps Intrinsically Disordered Proteins for Degradation.
    Biran A; Myers N; Steinberger S; Adler J; Riutin M; Broennimann K; Reuven N; Shaul Y
    Cells; 2022 Oct; 11(20):. PubMed ID: 36291102
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.