BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 28724523)

  • 1. Savolitinib Heads for Phase III Trial in PRCC.
    Cancer Discov; 2017 Sep; 7(9):OF4. PubMed ID: 28724523
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Savolitinib for MET-driven papillary renal cell carcinoma.
    Gilbert JA
    Lancet Oncol; 2017 Aug; 18(8):e440. PubMed ID: 28669737
    [No Abstract]   [Full Text] [Related]  

  • 3. Efficacy of Savolitinib vs Sunitinib in Patients With MET-Driven Papillary Renal Cell Carcinoma: The SAVOIR Phase 3 Randomized Clinical Trial.
    Choueiri TK; Heng DYC; Lee JL; Cancel M; Verheijen RB; Mellemgaard A; Ottesen LH; Frigault MM; L'Hernault A; Szijgyarto Z; Signoretti S; Albiges L
    JAMA Oncol; 2020 Aug; 6(8):1247-1255. PubMed ID: 32469384
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biomarker-Based Phase II Trial of Savolitinib in Patients With Advanced Papillary Renal Cell Cancer.
    Choueiri TK; Plimack E; Arkenau HT; Jonasch E; Heng DYC; Powles T; Frigault MM; Clark EA; Handzel AA; Gardner H; Morgan S; Albiges L; Pal SK
    J Clin Oncol; 2017 Sep; 35(26):2993-3001. PubMed ID: 28644771
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient-Derived Xenograft Models.
    Schuller AG; Barry ER; Jones RD; Henry RE; Frigault MM; Beran G; Linsenmayer D; Hattersley M; Smith A; Wilson J; Cairo S; Déas O; Nicolle D; Adam A; Zinda M; Reimer C; Fawell SE; Clark EA; D'Cruz CM
    Clin Cancer Res; 2015 Jun; 21(12):2811-9. PubMed ID: 25779944
    [TBL] [Abstract][Full Text] [Related]  

  • 6. First-in-Human Phase I Study of the Selective MET Inhibitor, Savolitinib, in Patients with Advanced Solid Tumors: Safety, Pharmacokinetics, and Antitumor Activity.
    Gan HK; Millward M; Hua Y; Qi C; Sai Y; Su W; Wang J; Zhang L; Frigault MM; Morgan S; Yang L; Lickliter JD
    Clin Cancer Res; 2019 Aug; 25(16):4924-4932. PubMed ID: 30952639
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Savolitinib: First Approval.
    Markham A
    Drugs; 2021 Sep; 81(14):1665-1670. PubMed ID: 34455538
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Osimertinib plus savolitinib in patients with EGFR mutation-positive, MET-amplified, non-small-cell lung cancer after progression on EGFR tyrosine kinase inhibitors: interim results from a multicentre, open-label, phase 1b study.
    Sequist LV; Han JY; Ahn MJ; Cho BC; Yu H; Kim SW; Yang JC; Lee JS; Su WC; Kowalski D; Orlov S; Cantarini M; Verheijen RB; Mellemgaard A; Ottesen L; Frewer P; Ou X; Oxnard G
    Lancet Oncol; 2020 Mar; 21(3):373-386. PubMed ID: 32027846
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A phase Ib study of the highly selective MET-TKI savolitinib plus gefitinib in patients with EGFR-mutated, MET-amplified advanced non-small-cell lung cancer.
    Yang JJ; Fang J; Shu YQ; Chang JH; Chen GY; He JX; Li W; Liu XQ; Yang N; Zhou C; Huang JA; Frigault MM; Hartmaier R; Ahmed GF; Egile C; Morgan S; Verheijen RB; Mellemgaard A; Yang L; Wu YL
    Invest New Drugs; 2021 Apr; 39(2):477-487. PubMed ID: 33052556
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Therapeutic strategies in METex14 skipping mutated non-small cell lung cancer.
    Drusbosky LM; Dawar R; Rodriguez E; Ikpeazu CV
    J Hematol Oncol; 2021 Aug; 14(1):129. PubMed ID: 34425853
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma.
    Diamond JR; Salgia R; Varella-Garcia M; Kanteti R; LoRusso PM; Clark JW; Xu LG; Wilner K; Eckhardt SG; Ching KA; Lira ME; Schoenmakers EF; Christensen JG; Camidge DR
    J Clin Oncol; 2013 Jun; 31(16):e254-8. PubMed ID: 23610116
    [No Abstract]   [Full Text] [Related]  

  • 12. Re: Toni K. Choueiri, Daniel Y.C. Heng, Jae Lyun Lee, et al. Efficacy of Savolitinib vs Sunitinib in Patients With MET-Driven Papillary Renal Cell Carcinoma: The SAVOIR Phase 3 Randomized Clinical Trial. JAMA Oncol. In press. https://doi.org/10.1001/jamaoncol.2020.2218: SAVOIR: From Own Goal to Winning Goal?
    Mollica V; Rizzo A; Massari F
    Eur Urol Oncol; 2020 Aug; 3(4):561-562. PubMed ID: 32653414
    [No Abstract]   [Full Text] [Related]  

  • 13. Papillary renal cell carcinoma: current progress and future directions.
    Twardowski PW; Mack PC; Lara PN
    Clin Genitourin Cancer; 2014 Apr; 12(2):74-9. PubMed ID: 24629521
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Papillary renal cell carcinoma: analysis of germline mutations in the MET proto-oncogene in a clinic-based population.
    Lindor NM; Dechet CB; Greene MH; Jenkins RB; Zincke MT; Weaver AL; Wilson M; Zincke H; Liu W
    Genet Test; 2001; 5(2):101-6. PubMed ID: 11551094
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crizotinib achieves long-lasting disease control in advanced papillary renal-cell carcinoma type 1 patients with MET mutations or amplification. EORTC 90101 CREATE trial.
    Schöffski P; Wozniak A; Escudier B; Rutkowski P; Anthoney A; Bauer S; Sufliarsky J; van Herpen C; Lindner LH; Grünwald V; Zakotnik B; Lerut E; Debiec-Rychter M; Marréaud S; Lia M; Raveloarivahy T; Collette S; Albiges L
    Eur J Cancer; 2017 Dec; 87():147-163. PubMed ID: 29149761
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Response to crizotinib in a patient with MET-mutant papillary renal cell cancer after progression on tivantinib.
    Stein MN; Hirshfield KM; Zhong H; Singer EA; Ali SM; Ganesan S
    Eur Urol; 2015 Feb; 67(2):353-4. PubMed ID: 25457019
    [No Abstract]   [Full Text] [Related]  

  • 17. Papillary renal cell carcinoma: A review of the current therapeutic landscape.
    Courthod G; Tucci M; Di Maio M; Scagliotti GV
    Crit Rev Oncol Hematol; 2015 Oct; 96(1):100-12. PubMed ID: 26052049
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The molecular characterization and therapeutic strategies of papillary renal cell carcinoma.
    Chen Q; Cheng L; Li Q
    Expert Rev Anticancer Ther; 2019 Feb; 19(2):169-175. PubMed ID: 30474436
    [No Abstract]   [Full Text] [Related]  

  • 19. Once-daily savolitinib in Chinese patients with pulmonary sarcomatoid carcinomas and other non-small-cell lung cancers harbouring MET exon 14 skipping alterations: a multicentre, single-arm, open-label, phase 2 study.
    Lu S; Fang J; Li X; Cao L; Zhou J; Guo Q; Liang Z; Cheng Y; Jiang L; Yang N; Han Z; Shi J; Chen Y; Xu H; Zhang H; Chen G; Ma R; Sun S; Fan Y; Li J; Luo X; Wang L; Ren Y; Su W
    Lancet Respir Med; 2021 Oct; 9(10):1154-1164. PubMed ID: 34166627
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acquired savolitinib resistance in non-small cell lung cancer arises via multiple mechanisms that converge on MET-independent mTOR and MYC activation.
    Henry RE; Barry ER; Castriotta L; Ladd B; Markovets A; Beran G; Ren Y; Zhou F; Adam A; Zinda M; Reimer C; Qing W; Su W; Clark E; D'Cruz CM; Schuller AG
    Oncotarget; 2016 Sep; 7(36):57651-57670. PubMed ID: 27472392
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.