BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

493 related articles for article (PubMed ID: 28728108)

  • 1. New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents.
    Roldán-Peña JM; Alejandre-Ramos D; López Ó; Maya I; Lagunes I; Padrón JM; Peña-Altamira LE; Bartolini M; Monti B; Bolognesi ML; Fernández-Bolaños JG
    Eur J Med Chem; 2017 Sep; 138():761-773. PubMed ID: 28728108
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
    Riazimontazer E; Sadeghpour H; Nadri H; Sakhteman A; Tüylü Küçükkılınç T; Miri R; Edraki N
    Bioorg Chem; 2019 Aug; 89():103006. PubMed ID: 31158577
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors.
    Roldán-Peña JM; Romero-Real V; Hicke J; Maya I; Franconetti A; Lagunes I; Padrón JM; Petralla S; Poeta E; Naldi M; Bartolini M; Monti B; Bolognesi ML; López Ó; Fernández-Bolaños JG
    Eur J Med Chem; 2019 Nov; 181():111550. PubMed ID: 31376562
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Multifunctional tacrine-flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease.
    Li SY; Wang XB; Xie SS; Jiang N; Wang KD; Yao HQ; Sun HB; Kong LY
    Eur J Med Chem; 2013 Nov; 69():632-46. PubMed ID: 24095756
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tacrine-hydroxamate derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.
    Xu A; He F; Zhang X; Li X; Ran Y; Wei C; James Chou C; Zhang R; Wu J
    Bioorg Chem; 2020 May; 98():103721. PubMed ID: 32193030
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents.
    Luo W; Li YP; He Y; Huang SL; Li D; Gu LQ; Huang ZS
    Eur J Med Chem; 2011 Jun; 46(6):2609-16. PubMed ID: 21497959
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J; Yang H; Chen Y; Lin H; Li Q; Mo J; Bian Y; Pei Y; Sun H
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):496-506. PubMed ID: 29405075
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New racemic annulated pyrazolo[1,2-b]phthalazines as tacrine-like AChE inhibitors with potential use in Alzheimer's disease.
    Jalili-Baleh L; Nadri H; Moradi A; Bukhari SNA; Shakibaie M; Jafari M; Golshani M; Homayouni Moghadam F; Firoozpour L; Asadipour A; Emami S; Khoobi M; Foroumadi A
    Eur J Med Chem; 2017 Oct; 139():280-289. PubMed ID: 28803044
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids.
    Benchekroun M; Bartolini M; Egea J; Romero A; Soriano E; Pudlo M; Luzet V; Andrisano V; Jimeno ML; López MG; Wehle S; Gharbi T; Refouvelet B; de Andrés L; Herrera-Arozamena C; Monti B; Bolognesi ML; Rodríguez-Franco MI; Decker M; Marco-Contelles J; Ismaili L
    ChemMedChem; 2015 Mar; 10(3):523-39. PubMed ID: 25537267
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of novel tacrine-dipicolylamine dimers that are multiple-target-directed ligands with potential to treat Alzheimer's disease.
    Zhang P; Wang Z; Mou C; Zou J; Xie Y; Liu Z; Benjamin Naman C; Mao Y; Wei J; Huang X; Dong J; Yang M; Wang N; Jin H; Liu F; Lin D; Liu H; Zhou F; He S; Zhang B; Cui W
    Bioorg Chem; 2021 Nov; 116():105387. PubMed ID: 34628225
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pterostilbene-O-acetamidoalkylbenzylamines derivatives as novel dual inhibitors of cholinesterase with anti-β-amyloid aggregation and antioxidant properties for the treatment of Alzheimer's disease.
    Li Y; Qiang X; Li Y; Yang X; Luo L; Xiao G; Cao Z; Tan Z; Deng Y
    Bioorg Med Chem Lett; 2016 Apr; 26(8):2035-9. PubMed ID: 26947607
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Thiratmatrakul S; Yenjai C; Waiwut P; Vajragupta O; Reubroycharoen P; Tohda M; Boonyarat C
    Eur J Med Chem; 2014 Mar; 75():21-30. PubMed ID: 24508831
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and β-amyloid-reducing properties.
    Fernández-Bachiller MI; Pérez C; Monjas L; Rademann J; Rodríguez-Franco MI
    J Med Chem; 2012 Feb; 55(3):1303-17. PubMed ID: 22243648
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease.
    Chalupova K; Korabecny J; Bartolini M; Monti B; Lamba D; Caliandro R; Pesaresi A; Brazzolotto X; Gastellier AJ; Nachon F; Pejchal J; Jarosova M; Hepnarova V; Jun D; Hrabinova M; Dolezal R; Zdarova Karasova J; Mzik M; Kristofikova Z; Misik J; Muckova L; Jost P; Soukup O; Benkova M; Setnicka V; Habartova L; Chvojkova M; Kleteckova L; Vales K; Mezeiova E; Uliassi E; Valis M; Nepovimova E; Bolognesi ML; Kuca K
    Eur J Med Chem; 2019 Apr; 168():491-514. PubMed ID: 30851693
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and functional survey of new Tacrine analogs modified with nitroxides or their precursors.
    Kálai T; Altman R; Maezawa I; Balog M; Morisseau C; Petrlova J; Hammock BD; Jin LW; Trudell JR; Voss JC; Hideg K
    Eur J Med Chem; 2014 Apr; 77():343-50. PubMed ID: 24657571
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New tacrine-acridine hybrids as promising multifunctional drugs for potential treatment of Alzheimer's disease.
    Chufarova N; Czarnecka K; Skibiński R; Cuchra M; Majsterek I; Szymański P
    Arch Pharm (Weinheim); 2018 Jul; 351(7):e1800050. PubMed ID: 29870588
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease.
    Chao X; He X; Yang Y; Zhou X; Jin M; Liu S; Cheng Z; Liu P; Wang Y; Yu J; Tan Y; Huang Y; Qin J; Rapposelli S; Pi R
    Bioorg Med Chem Lett; 2012 Oct; 22(20):6498-502. PubMed ID: 22981331
    [TBL] [Abstract][Full Text] [Related]  

  • 18. O-Hydroxyl- or o-amino benzylamine-tacrine hybrids: multifunctional biometals chelators, antioxidants, and inhibitors of cholinesterase activity and amyloid-β aggregation.
    Mao F; Huang L; Luo Z; Liu A; Lu C; Xie Z; Li X
    Bioorg Med Chem; 2012 Oct; 20(19):5884-92. PubMed ID: 22944335
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and bioevaluation of new tacrine-cinnamic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Chen Y; Zhu J; Mo J; Yang H; Jiang X; Lin H; Gu K; Pei Y; Wu L; Tan R; Hou J; Chen J; Lv Y; Bian Y; Sun H
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):290-302. PubMed ID: 29278947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS; Xie SS; Li SY; Pan LF; Wang XB; Kong LY
    Bioorg Med Chem; 2014 Nov; 22(21):6089-104. PubMed ID: 25282654
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.