BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

325 related articles for article (PubMed ID: 28729482)

  • 1. BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.
    Tacconi EM; Lai X; Folio C; Porru M; Zonderland G; Badie S; Michl J; Sechi I; Rogier M; Matía García V; Batra AS; Rueda OM; Bouwman P; Jonkers J; Ryan A; Reina-San-Martin B; Hui J; Tang N; Bruna A; Biroccio A; Tarsounas M
    EMBO Mol Med; 2017 Oct; 9(10):1398-1414. PubMed ID: 28729482
    [TBL] [Abstract][Full Text] [Related]  

  • 2. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair.
    Kais Z; Rondinelli B; Holmes A; O'Leary C; Kozono D; D'Andrea AD; Ceccaldi R
    Cell Rep; 2016 Jun; 15(11):2488-99. PubMed ID: 27264184
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.
    Schlacher K; Wu H; Jasin M
    Cancer Cell; 2012 Jul; 22(1):106-16. PubMed ID: 22789542
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links.
    Rickman KA; Noonan RJ; Lach FP; Sridhar S; Wang AT; Abhyankar A; Huang A; Kelly M; Auerbach AD; Smogorzewska A
    Genes Dev; 2020 Jun; 34(11-12):832-846. PubMed ID: 32354836
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication.
    Zhu W; Dutta A
    Mol Cell Biol; 2006 Jun; 26(12):4601-11. PubMed ID: 16738325
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2- and RAD51-associated homologous recombination in response to DNA damage.
    Ohashi A; Zdzienicka MZ; Chen J; Couch FJ
    J Biol Chem; 2005 Apr; 280(15):14877-83. PubMed ID: 15671039
    [TBL] [Abstract][Full Text] [Related]  

  • 7. siRNA depletion of BRCA1, but not BRCA2, causes increased genome instability in Fanconi anemia cells.
    Bruun D; Folias A; Akkari Y; Cox Y; Olson S; Moses R
    DNA Repair (Amst); 2003 Sep; 2(9):1007-13. PubMed ID: 12967657
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inducibility of nuclear Rad51 foci after DNA damage distinguishes all Fanconi anemia complementation groups from D1/BRCA2.
    Godthelp BC; Wiegant WW; Waisfisz Q; Medhurst AL; Arwert F; Joenje H; Zdzienicka MZ
    Mutat Res; 2006 Feb; 594(1-2):39-48. PubMed ID: 16154163
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CtIP mediates replication fork recovery in a FANCD2-regulated manner.
    Yeo JE; Lee EH; Hendrickson EA; Sobeck A
    Hum Mol Genet; 2014 Jul; 23(14):3695-705. PubMed ID: 24556218
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proteasome function is required for DNA damage response and fanconi anemia pathway activation.
    Jacquemont C; Taniguchi T
    Cancer Res; 2007 Aug; 67(15):7395-405. PubMed ID: 17671210
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Therapeutic exploitation of tumor cell defects in homologous recombination.
    Powell SN; Kachnic LA
    Anticancer Agents Med Chem; 2008 May; 8(4):448-60. PubMed ID: 18473729
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exploring the link between MORF4L1 and risk of breast cancer.
    Martrat G; Maxwell CM; Tominaga E; Porta-de-la-Riva M; Bonifaci N; Gómez-Baldó L; Bogliolo M; Lázaro C; Blanco I; Brunet J; Aguilar H; Fernández-Rodríguez J; Seal S; Renwick A; Rahman N; Kühl J; Neveling K; Schindler D; Ramírez MJ; Castellà M; Hernández G; ; Easton DF; Peock S; Cook M; Oliver CT; Frost D; Platte R; Evans DG; Lalloo F; Eeles R; Izatt L; Chu C; Davidson R; Ong KR; Cook J; Douglas F; Hodgson S; Brewer C; Morrison PJ; Porteous M; Peterlongo P; Manoukian S; Peissel B; Zaffaroni D; Roversi G; Barile M; Viel A; Pasini B; Ottini L; Putignano AL; Savarese A; Bernard L; Radice P; Healey S; Spurdle A; Chen X; Beesley J; ; Rookus MA; Verhoef S; Tilanus-Linthorst MA; Vreeswijk MP; Asperen CJ; Bodmer D; Ausems MG; van Os TA; Blok MJ; Meijers-Heijboer HE; Hogervorst FB; ; Goldgar DE; Buys S; John EM; Miron A; Southey M; Daly MB; ; ; Harbst K; Borg A; Rantala J; Barbany-Bustinza G; Ehrencrona H; Stenmark-Askmalm M; Kaufman B; Laitman Y; Milgrom R; Friedman E; Domchek SM; Nathanson KL; Rebbeck TR; Johannsson OT; Couch FJ; Wang X; Fredericksen Z; Cuadras D; Moreno V; Pientka FK; Depping R; Caldés T; Osorio A; Benítez J; Bueren J; Heikkinen T; Nevanlinna H; Hamann U; Torres D; Caligo MA; Godwin AK; Imyanitov EN; Janavicius R; ; Sinilnikova OM; Stoppa-Lyonnet D; Mazoyer S; Verny-Pierre C; Castera L; de Pauw A; Bignon YJ; Uhrhammer N; Peyrat JP; Vennin P; Ferrer SF; Collonge-Rame MA; Mortemousque I; McGuffog L; Chenevix-Trench G; Pereira-Smith OM; Antoniou AC; Cerón J; Tominaga K; Surrallés J; Pujana MA
    Breast Cancer Res; 2011 Apr; 13(2):R40. PubMed ID: 21466675
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BRCA1-Dependent and Independent Recruitment of PALB2-BRCA2-RAD51 in the DNA Damage Response and Cancer.
    Foo TK; Xia B
    Cancer Res; 2022 Sep; 82(18):3191-3197. PubMed ID: 35819255
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins.
    Prakash R; Zhang Y; Feng W; Jasin M
    Cold Spring Harb Perspect Biol; 2015 Apr; 7(4):a016600. PubMed ID: 25833843
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differences in Expression of Key DNA Damage Repair Genes after Epigenetic-Induced BRCAness Dictate Synthetic Lethality with PARP1 Inhibition.
    Wiegmans AP; Yap PY; Ward A; Lim YC; Khanna KK
    Mol Cancer Ther; 2015 Oct; 14(10):2321-31. PubMed ID: 26294743
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance.
    Johnson N; Johnson SF; Yao W; Li YC; Choi YE; Bernhardy AJ; Wang Y; Capelletti M; Sarosiek KA; Moreau LA; Chowdhury D; Wickramanayake A; Harrell MI; Liu JF; D'Andrea AD; Miron A; Swisher EM; Shapiro GI
    Proc Natl Acad Sci U S A; 2013 Oct; 110(42):17041-6. PubMed ID: 24085845
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The F-Box Domain-Dependent Activity of EMI1 Regulates PARPi Sensitivity in Triple-Negative Breast Cancers.
    Marzio A; Puccini J; Kwon Y; Maverakis NK; Arbini A; Sung P; Bar-Sagi D; Pagano M
    Mol Cell; 2019 Jan; 73(2):224-237.e6. PubMed ID: 30554948
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
    Zong D; Adam S; Wang Y; Sasanuma H; Callén E; Murga M; Day A; Kruhlak MJ; Wong N; Munro M; Ray Chaudhuri A; Karim B; Xia B; Takeda S; Johnson N; Durocher D; Nussenzweig A
    Mol Cell; 2019 Mar; 73(6):1267-1281.e7. PubMed ID: 30704900
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Replication Fork Reversal: Players and Guardians.
    Quinet A; Lemaçon D; Vindigni A
    Mol Cell; 2017 Dec; 68(5):830-833. PubMed ID: 29220651
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cediranib suppresses homology-directed DNA repair through down-regulation of BRCA1/2 and RAD51.
    Kaplan AR; Gueble SE; Liu Y; Oeck S; Kim H; Yun Z; Glazer PM
    Sci Transl Med; 2019 May; 11(492):. PubMed ID: 31092693
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.