624 related articles for article (PubMed ID: 28729730)
1. A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease mice.
Suelves N; Kirkham-McCarthy L; Lahue RS; Ginés S
Sci Rep; 2017 Jul; 7(1):6082. PubMed ID: 28729730
[TBL] [Abstract][Full Text] [Related]
2. The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice.
Jia H; Wang Y; Morris CD; Jacques V; Gottesfeld JM; Rusche JR; Thomas EA
PLoS One; 2016; 11(3):e0152498. PubMed ID: 27031333
[TBL] [Abstract][Full Text] [Related]
3. HDAC3 deacetylates the DNA mismatch repair factor MutSβ to stimulate triplet repeat expansions.
Williams GM; Paschalis V; Ortega J; Muskett FW; Hodgkinson JT; Li GM; Schwabe JWR; Lahue RS
Proc Natl Acad Sci U S A; 2020 Sep; 117(38):23597-23605. PubMed ID: 32900932
[TBL] [Abstract][Full Text] [Related]
4. Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.
Giralt A; Puigdellívol M; Carretón O; Paoletti P; Valero J; Parra-Damas A; Saura CA; Alberch J; Ginés S
Hum Mol Genet; 2012 Mar; 21(6):1203-16. PubMed ID: 22116937
[TBL] [Abstract][Full Text] [Related]
5. Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in mice.
Lloret A; Dragileva E; Teed A; Espinola J; Fossale E; Gillis T; Lopez E; Myers RH; MacDonald ME; Wheeler VC
Hum Mol Genet; 2006 Jun; 15(12):2015-24. PubMed ID: 16687439
[TBL] [Abstract][Full Text] [Related]
6. Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice.
Kovalenko M; Erdin S; Andrew MA; St Claire J; Shaughnessey M; Hubert L; Neto JL; Stortchevoi A; Fass DM; Mouro Pinto R; Haggarty SJ; Wilson JH; Talkowski ME; Wheeler VC
Elife; 2020 Sep; 9():. PubMed ID: 32990597
[TBL] [Abstract][Full Text] [Related]
7. Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease.
Jia H; Pallos J; Jacques V; Lau A; Tang B; Cooper A; Syed A; Purcell J; Chen Y; Sharma S; Sangrey GR; Darnell SB; Plasterer H; Sadri-Vakili G; Gottesfeld JM; Thompson LM; Rusche JR; Marsh JL; Thomas EA
Neurobiol Dis; 2012 May; 46(2):351-61. PubMed ID: 22590724
[TBL] [Abstract][Full Text] [Related]
8. Multiple clinical features of Huntington's disease correlate with mutant HTT gene CAG repeat lengths and neurodegeneration.
Podvin S; Reardon HT; Yin K; Mosier C; Hook V
J Neurol; 2019 Mar; 266(3):551-564. PubMed ID: 29956026
[TBL] [Abstract][Full Text] [Related]
9. Intravenous immunoglobulin ameliorates motor and cognitive deficits and neuropathology in R6/2 mouse model of Huntington's disease by decreasing mutant huntingtin protein level and normalizing NF-κB signaling pathway.
Liu SY; Yu XL; Zhu J; Liu XM; Zhang Y; Dong QX; Ma S; Liu RT
Brain Res; 2018 Oct; 1697():21-33. PubMed ID: 29902468
[TBL] [Abstract][Full Text] [Related]
10. Treadmill exercise delays the onset of non-motor behaviors and striatal pathology in the CAG
Stefanko DP; Shah VD; Yamasaki WK; Petzinger GM; Jakowec MW
Neurobiol Dis; 2017 Sep; 105():15-32. PubMed ID: 28502806
[TBL] [Abstract][Full Text] [Related]
11. A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease.
Aldous SG; Smith EJ; Landles C; Osborne GF; Cañibano-Pico M; Nita IM; Phillips J; Zhang Y; Jin B; Hirst MB; Benn CL; Bond BC; Edelmann W; Greene JR; Bates GP
Brain; 2024 May; 147(5):1784-1798. PubMed ID: 38387080
[TBL] [Abstract][Full Text] [Related]
12. Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases.
Handley RR; Reid SJ; Brauning R; Maclean P; Mears ER; Fourie I; Patassini S; Cooper GJS; Rudiger SR; McLaughlan CJ; Verma PJ; Gusella JF; MacDonald ME; Waldvogel HJ; Bawden CS; Faull RLM; Snell RG
Proc Natl Acad Sci U S A; 2017 Dec; 114(52):E11293-E11302. PubMed ID: 29229845
[TBL] [Abstract][Full Text] [Related]
13. Differential proteomic and genomic profiling of mouse striatal cell model of Huntington's disease and control; probable implications to the disease biology.
Choudhury KR; Das S; Bhattacharyya NP
J Proteomics; 2016 Jan; 132():155-66. PubMed ID: 26581643
[TBL] [Abstract][Full Text] [Related]
14. Epigenetics of Huntington's Disease.
Bassi S; Tripathi T; Monziani A; Di Leva F; Biagioli M
Adv Exp Med Biol; 2017; 978():277-299. PubMed ID: 28523552
[TBL] [Abstract][Full Text] [Related]
15. Protection by dietary restriction in the YAC128 mouse model of Huntington's disease: Relation to genes regulating histone acetylation and HTT.
Moreno CL; Ehrlich ME; Mobbs CV
Neurobiol Dis; 2016 Jan; 85():25-34. PubMed ID: 26485309
[TBL] [Abstract][Full Text] [Related]
16. Loss of striatal 90-kDa ribosomal S6 kinase (Rsk) is a key factor for motor, synaptic and transcription dysfunction in Huntington's disease.
Anglada-Huguet M; Giralt A; Rué L; Alberch J; Xifró X
Biochim Biophys Acta; 2016 Jul; 1862(7):1255-66. PubMed ID: 27063456
[TBL] [Abstract][Full Text] [Related]
17. Genetic Contributors to Intergenerational CAG Repeat Instability in Huntington's Disease Knock-In Mice.
Neto JL; Lee JM; Afridi A; Gillis T; Guide JR; Dempsey S; Lager B; Alonso I; Wheeler VC; Pinto RM
Genetics; 2017 Feb; 205(2):503-516. PubMed ID: 27913616
[TBL] [Abstract][Full Text] [Related]
18. Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models.
Franich NR; Basso M; André EA; Ochaba J; Kumar A; Thein S; Fote G; Kachemov M; Lau AL; Yeung SY; Osmand A; Zeitlin SO; Ratan RR; Thompson LM; Steffan JS
J Huntingtons Dis; 2018; 7(2):137-150. PubMed ID: 29843246
[TBL] [Abstract][Full Text] [Related]
19. Loss of huntingtin function slows synaptic vesicle endocytosis in striatal neurons from the htt
McAdam RL; Morton A; Gordon SL; Alterman JF; Khvorova A; Cousin MA; Smillie KJ
Neurobiol Dis; 2020 Feb; 134():104637. PubMed ID: 31614197
[TBL] [Abstract][Full Text] [Related]
20. Altered Aconitase 2 Activity in Huntington's Disease Peripheral Blood Cells and Mouse Model Striatum.
Chen CM; Wu YR; Chang KH
Int J Mol Sci; 2017 Nov; 18(11):. PubMed ID: 29160844
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
