627 related articles for article (PubMed ID: 28729730)
21. Targeting HDAC3 Activity with RGFP966 Protects Against Retinal Ganglion Cell Nuclear Atrophy and Apoptosis After Optic Nerve Injury.
Schmitt HM; Schlamp CL; Nickells RW
J Ocul Pharmacol Ther; 2018 Apr; 34(3):260-273. PubMed ID: 29211617
[TBL] [Abstract][Full Text] [Related]
22. Decreased Myocyte Enhancer Factor 2 Levels in the Hippocampus of Huntington's Disease Mice Are Related to Cognitive Dysfunction.
Vidal-Sancho L; Fernández-García S; Solés-Tarrés I; Alberch J; Xifró X
Mol Neurobiol; 2020 Nov; 57(11):4549-4562. PubMed ID: 32757160
[TBL] [Abstract][Full Text] [Related]
23. Disassociation of histone deacetylase-3 from normal huntingtin underlies mutant huntingtin neurotoxicity.
Bardai FH; Verma P; Smith C; Rawat V; Wang L; D'Mello SR
J Neurosci; 2013 Jul; 33(29):11833-8. PubMed ID: 23864673
[TBL] [Abstract][Full Text] [Related]
24. Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.
Pinto RM; Dragileva E; Kirby A; Lloret A; Lopez E; St Claire J; Panigrahi GB; Hou C; Holloway K; Gillis T; Guide JR; Cohen PE; Li GM; Pearson CE; Daly MJ; Wheeler VC
PLoS Genet; 2013 Oct; 9(10):e1003930. PubMed ID: 24204323
[TBL] [Abstract][Full Text] [Related]
25. Cell-Autonomous and Non-cell-Autonomous Pathogenic Mechanisms in Huntington's Disease: Insights from In Vitro and In Vivo Models.
Creus-Muncunill J; Ehrlich ME
Neurotherapeutics; 2019 Oct; 16(4):957-978. PubMed ID: 31529216
[TBL] [Abstract][Full Text] [Related]
26. Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype.
Wegrzynowicz M; Bichell TJ; Soares BD; Loth MK; McGlothan JS; Mori S; Alikhan FS; Hua K; Coughlin JM; Holt HK; Jetter CS; Pomper MG; Osmand AP; Guilarte TR; Bowman AB
J Huntingtons Dis; 2015; 4(1):17-36. PubMed ID: 26333255
[TBL] [Abstract][Full Text] [Related]
27. Pharmacogenetic modulation of STEP improves motor and cognitive function in a mouse model of Huntington's disease.
García-Forn M; Martínez-Torres S; García-Díaz Barriga G; Alberch J; Milà M; Azkona G; Pérez-Navarro E
Neurobiol Dis; 2018 Dec; 120():88-97. PubMed ID: 30176350
[TBL] [Abstract][Full Text] [Related]
28. Cognitive decline in Huntington's disease expansion gene carriers.
Baake V; Reijntjes RHAM; Dumas EM; Thompson JC; ; Roos RAC
Cortex; 2017 Oct; 95():51-62. PubMed ID: 28843844
[TBL] [Abstract][Full Text] [Related]
29. N-terminal mutant huntingtin deposition correlates with CAG repeat length and symptom onset, but not neuronal loss in Huntington's disease.
Layburn FE; Tan AYS; Mehrabi NF; Curtis MA; Tippett LJ; Turner CP; Riguet N; Aeschbach L; Lashuel HA; Dragunow M; Faull RLM; Singh-Bains MK
Neurobiol Dis; 2022 Nov; 174():105884. PubMed ID: 36220612
[TBL] [Abstract][Full Text] [Related]
30. The HDAC3 inhibitor RGFP966 ameliorated ischemic brain damage by downregulating the AIM2 inflammasome.
Zhang MJ; Zhao QC; Xia MX; Chen J; Chen YT; Cao X; Liu Y; Yuan ZQ; Wang XY; Xu Y
FASEB J; 2020 Jan; 34(1):648-662. PubMed ID: 31914678
[TBL] [Abstract][Full Text] [Related]
31. Ellagic acid rescues motor and cognitive deficits in the R6/2 mouse model of Huntington's disease by lowering mutant huntingtin protein.
Sun X; Zhu J; Sun XY; Ji M; Yu XL; Liu RT
Food Funct; 2020 Feb; 11(2):1334-1348. PubMed ID: 32043503
[TBL] [Abstract][Full Text] [Related]
32. The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.
Thomas EA; Coppola G; Desplats PA; Tang B; Soragni E; Burnett R; Gao F; Fitzgerald KM; Borok JF; Herman D; Geschwind DH; Gottesfeld JM
Proc Natl Acad Sci U S A; 2008 Oct; 105(40):15564-9. PubMed ID: 18829438
[TBL] [Abstract][Full Text] [Related]
33. The Complexity of Clinical Huntington's Disease: Developments in Molecular Genetics, Neuropathology and Neuroimaging Biomarkers.
Tippett LJ; Waldvogel HJ; Snell RG; Vonsattel JP; Young AB; Faull RLM
Adv Neurobiol; 2017; 15():129-161. PubMed ID: 28674980
[TBL] [Abstract][Full Text] [Related]
34. AAV5-miHTT-mediated huntingtin lowering improves brain health in a Huntington's disease mouse model.
Thomson SB; Stam A; Brouwers C; Fodale V; Bresciani A; Vermeulen M; Mostafavi S; Petkau TL; Hill A; Yung A; Russell-Schulz B; Kozlowski P; MacKay A; Ma D; Beg MF; Evers MM; Vallès A; Leavitt BR
Brain; 2023 Jun; 146(6):2298-2315. PubMed ID: 36508327
[TBL] [Abstract][Full Text] [Related]
35. Alterations of striatal indirect pathway neurons precede motor deficits in two mouse models of Huntington's disease.
Sebastianutto I; Cenci MA; Fieblinger T
Neurobiol Dis; 2017 Sep; 105():117-131. PubMed ID: 28578004
[TBL] [Abstract][Full Text] [Related]
36. Inhibition of Histone Deacetylase 3 Restores Amyloid-β Oligomer-Induced Plasticity Deficit in Hippocampal CA1 Pyramidal Neurons.
Krishna K; Behnisch T; Sajikumar S
J Alzheimers Dis; 2016; 51(3):783-91. PubMed ID: 26890755
[TBL] [Abstract][Full Text] [Related]
37. Transcriptional correlates of the pathological phenotype in a Huntington's disease mouse model.
Gallardo-Orihuela A; Hervás-Corpión I; Hierro-Bujalance C; Sanchez-Sotano D; Jiménez-Gómez G; Mora-López F; Campos-Caro A; Garcia-Alloza M; Valor LM
Sci Rep; 2019 Dec; 9(1):18696. PubMed ID: 31822756
[TBL] [Abstract][Full Text] [Related]
38. Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis.
Reis SA; Thompson MN; Lee JM; Fossale E; Kim HH; Liao JK; Moskowitz MA; Shaw SY; Dong L; Haggarty SJ; MacDonald ME; Seong IS
Hum Mol Genet; 2011 Jun; 20(12):2344-55. PubMed ID: 21447599
[TBL] [Abstract][Full Text] [Related]
39. Cognitive Dysfunction in Huntington's Disease: Humans, Mouse Models and Molecular Mechanisms.
Giralt A; Saavedra A; Alberch J; Pérez-Navarro E
J Huntingtons Dis; 2012; 1(2):155-73. PubMed ID: 25063329
[TBL] [Abstract][Full Text] [Related]
40. Dose-dependent reduction of somatic expansions but not Htt aggregates by di-valent siRNA-mediated silencing of MSH3 in HdhQ111 mice.
Driscoll R; Hampton L; Abraham NA; Larigan JD; Joseph NF; Hernandez-Vega JC; Geisler S; Yang FC; Deninger M; Tran DT; Khatri N; Godinho BMDC; Kinberger GA; Montagna DR; Hirst WD; Guardado CL; Glajch KE; Arnold HM; Gallant-Behm CL; Weihofen A
Sci Rep; 2024 Jan; 14(1):2061. PubMed ID: 38267530
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]