BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 28729838)

  • 1. Detection of Emodin Derived Glutathione Adduct in Normal Rats Administered with Large Dosage of Polygoni Multiflori Radix.
    Jiang LL; Zhao DS; Fan YX; Yu Q; Li P; Li HJ
    Front Pharmacol; 2017; 8():446. PubMed ID: 28729838
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exploration of components and mechanisms of Polygoni Multiflori Radix-induced hepatotoxicity using siRNA -mediated CYP3A4 or UGT1A1 knockdown liver cells.
    Hu YH; Li DK; Quan ZY; Wang CY; Zhou M; Sun ZX
    J Ethnopharmacol; 2021 Apr; 270():113845. PubMed ID: 33485974
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hepatotoxic assessment of Polygoni Multiflori Radix extract and toxicokinetic study of stilbene glucoside and anthraquinones in rats.
    Ma J; Zheng L; He YS; Li HJ
    J Ethnopharmacol; 2015 Mar; 162():61-8. PubMed ID: 25557036
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacokinetic studies unveiled the drug-drug interaction between trans-2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucopyranoside and emodin that may contribute to the idiosyncratic hepatotoxicity of Polygoni Multiflori Radix.
    Xing Y; Wang L; Wang C; Zhang Y; Zhang Y; Hu L; Gao X; Han L; Yang W
    J Pharm Biomed Anal; 2019 Feb; 164():672-680. PubMed ID: 30472586
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enhanced absorption and inhibited metabolism of emodin by 2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside: Possible mechanisms for Polygoni Multiflori Radix-induced liver injury.
    Yu Q; Jiang LL; Luo N; Fan YX; Ma J; Li P; Li HJ
    Chin J Nat Med; 2017 Jun; 15(6):451-457. PubMed ID: 28629535
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Polygoni Multiflori Radix derived anthraquinones alter bile acid disposition in sandwich-cultured rat hepatocytes.
    Kang L; Si L; Rao J; Li D; Wu Y; Wu S; Wu M; He S; Zhu W; Wu Y; Xu J; Li G; Huang J
    Toxicol In Vitro; 2017 Apr; 40():313-323. PubMed ID: 28161596
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatotoxicity of the Major Anthraquinones Derived From Polygoni Multiflori Radix Based on Bile Acid Homeostasis.
    Kang L; Li D; Jiang X; Zhang Y; Pan M; Hu Y; Si L; Zhang Y; Huang J
    Front Pharmacol; 2022; 13():878817. PubMed ID: 35662717
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transcriptome analysis to assess the cholestatic hepatotoxicity induced by Polygoni Multiflori Radix: Up-regulation of key enzymes of cholesterol and bile acid biosynthesis.
    Jiang LL; Zhao DS; Fan YX; Yu Q; Lai YS; Li P; Li HJ
    J Proteomics; 2018 Apr; 177():40-47. PubMed ID: 29438852
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reduction of emodin-8-O-ß-D-glucoside content participates in processing-based detoxification of polygoni multiflori radix.
    Wang X; Zhao G; Ju C; Dong L; Liu Y; Ding Z; Li W; Peng Y; Zheng J
    Phytomedicine; 2023 Jun; 114():154750. PubMed ID: 36990007
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Study on the protection of water extracts of Polygoni Multiflori Radix and Polygoni Multiflori Radix Praeparata against NAFLD and its mechanism.
    Lin L; Hao Z; Zhang S; Shi L; Lu B; Xu H; Ji L
    J Ethnopharmacol; 2020 Apr; 252():112577. PubMed ID: 31953200
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hepatoxicity of major constituents and extractions of Radix Polygoni Multiflori and Radix Polygoni Multiflori Praeparata.
    Yu J; Xie J; Mao XJ; Wang MJ; Li N; Wang J; Zhaori GT; Zhao RH
    J Ethnopharmacol; 2011 Oct; 137(3):1291-9. PubMed ID: 21840387
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of urine tauro-β-muricholic acid as a promising biomarker in Polygoni Multiflori Radix-induced hepatotoxicity by targeted metabolomics of bile acids.
    Zhao DS; Jiang LL; Fan YX; Dong LC; Ma J; Dong X; Xu XJ; Li P; Li HJ
    Food Chem Toxicol; 2017 Oct; 108(Pt B):532-542. PubMed ID: 28237774
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Idiosyncratic liver injury induced by bolus combination treatment with emodin and 2,3,5,4'-tetrahydroxystilbene-2-
    Li D; Lyu Y; Song Q; Lai YS; Zuo Z
    Front Pharmacol; 2022; 13():1017741. PubMed ID: 36225587
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside enhances the hepatotoxicity of emodin in vitro and in vivo.
    Li D; Song Q; Ji X; Lyu Y; Lai YS; Zuo Z
    Toxicol Lett; 2022 Jul; 365():74-85. PubMed ID: 35753641
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolomics profiling of Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparata extracts using UPLC-Q/TOF-MS.
    Zhang Z; Yang L; Huang X; Gao Y
    Chin Med; 2019; 14():46. PubMed ID: 31673279
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Accumulation of the Major Components from Polygoni Multiflori Radix in Liver and Kidney after Its Long-Term Oral Administrations in Rats.
    Li D; Lyu Y; Zhao J; Ji X; Zhang Y; Zuo Z
    Planta Med; 2022 Sep; 88(11):950-959. PubMed ID: 34521133
    [TBL] [Abstract][Full Text] [Related]  

  • 17. UHPLC-QQQ-MS/MS assay for the quantification of dianthrones as potential toxic markers of Polygonum multiflorum Thunb: applications for the standardization of traditional Chinese medicines (TCMs) with endogenous toxicity.
    Yang JB; Song YF; Liu Y; Gao HY; Wang Q; Wang Y; Cheng XL; Zuo TT; Hu XW; Wei F; Jin HT; Wang ST; Ma SC
    Chin Med; 2021 Jul; 16(1):51. PubMed ID: 34217329
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Influence of processing on pharmacokinetic of typical constituents in radix polygoni multiflori after oral administration by LC-ESI-MS/MS.
    Zhang L; Ma WF; Li J; He J; Zhang P; Zheng F; Zhang BL; Gao XM; Chang YX
    J Ethnopharmacol; 2013 Jun; 148(1):246-53. PubMed ID: 23608243
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hepatotoxic metabolites in
    Wang S; Kong X; Chen N; Hu P; Boucetta H; Hu Z; Xu X; Zhang P; Zhan X; Chang M; Cheng R; Wu W; Song M; Lu Y; Hang T
    Front Pharmacol; 2022; 13():1007284. PubMed ID: 36304159
    [No Abstract]   [Full Text] [Related]  

  • 20. [Comparative study on preparation of Polygoni Multiflori Radix based on hepatotoxic bioassay].
    Ma ZJ; Li XF; Lv Y; Jiang BQ; Zhao YL; Zhang YM; Zhao KJ; Wang JB; Xiao XH
    Zhongguo Zhong Yao Za Zhi; 2015 Jun; 40(12):2325-9. PubMed ID: 26591518
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.