BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 28733206)

  • 1. Omics-based identification of the combined effects of idiosyncratic drugs and inflammatory cytokines on the development of drug-induced liver injury.
    Jiang J; Mathijs K; Timmermans L; Claessen SM; Hecka A; Weusten J; Peters R; van Delft JH; Kleinjans JCS; Jennen DGJ; de Kok TM
    Toxicol Appl Pharmacol; 2017 Oct; 332():100-108. PubMed ID: 28733206
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity.
    Fredriksson L; Wink S; Herpers B; Benedetti G; Hadi M; de Bont H; Groothuis G; Luijten M; Danen E; de Graauw M; Meerman J; van de Water B
    Toxicol Sci; 2014 Jul; 140(1):144-59. PubMed ID: 24752500
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Implication of hepatic transporters (MDR1 and MRP2) in inflammation-associated idiosyncratic drug-induced hepatotoxicity investigated by microvolume cytometry.
    Saab L; Peluso J; Muller CD; Ubeaud-Sequier G
    Cytometry A; 2013 Apr; 83(4):403-8. PubMed ID: 23401306
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity.
    Herpers B; Wink S; Fredriksson L; Di Z; Hendriks G; Vrieling H; de Bont H; van de Water B
    Arch Toxicol; 2016 May; 90(5):1163-79. PubMed ID: 26026609
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Endoplasmic reticulum stress-mediated autophagy activation attenuates fumonisin B1 induced hepatotoxicity in vitro and in vivo.
    Singh MP; Kang SC
    Food Chem Toxicol; 2017 Dec; 110():371-382. PubMed ID: 29097114
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury.
    Laifenfeld D; Qiu L; Swiss R; Park J; Macoritto M; Will Y; Younis HS; Lawton M
    Toxicol Sci; 2014 Jan; 137(1):234-48. PubMed ID: 24136188
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity.
    Cosgrove BD; King BM; Hasan MA; Alexopoulos LG; Farazi PA; Hendriks BS; Griffith LG; Sorger PK; Tidor B; Xu JJ; Lauffenburger DA
    Toxicol Appl Pharmacol; 2009 Jun; 237(3):317-30. PubMed ID: 19362101
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis.
    Martínez L; Torres S; Baulies A; Alarcón-Vila C; Elena M; Fabriàs G; Casas J; Caballeria J; Fernandez-Checa JC; García-Ruiz C
    Oncotarget; 2015 Dec; 6(39):41479-96. PubMed ID: 26539645
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Perfluorooctanoic acid exposure induces endoplasmic reticulum stress in the liver and its effects are ameliorated by 4-phenylbutyrate.
    Yan S; Zhang H; Wang J; Zheng F; Dai J
    Free Radic Biol Med; 2015 Oct; 87():300-11. PubMed ID: 26159507
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Usefulness of in vitro combination assays of mitochondrial dysfunction and apoptosis for the estimation of potential risk of idiosyncratic drug induced liver injury.
    Goda K; Takahashi T; Kobayashi A; Shoda T; Kuno H; Sugai S
    J Toxicol Sci; 2016; 41(5):605-15. PubMed ID: 27665770
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Calcium Contributes to the Cytotoxic Interaction Between Diclofenac and Cytokines.
    Maiuri AR; Breier AB; Turkus JD; Ganey PE; Roth RA
    Toxicol Sci; 2016 Feb; 149(2):372-84. PubMed ID: 26609140
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The idiosyncratic drug-induced gene expression changes in HepG2 cells.
    Jiang J; Mathijs K; Timmermans L; Claessen SM; Hecka A; Weusten J; Peters R; van Delft JH; Kleinjans JCS; Jennen DGJ; de Kok TM
    Data Brief; 2017 Oct; 14():462-468. PubMed ID: 28831409
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis.
    Iorga A; Dara L; Kaplowitz N
    Int J Mol Sci; 2017 May; 18(5):. PubMed ID: 28486401
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells.
    Wei Y; Wang D; Topczewski F; Pagliassotti MJ
    Am J Physiol Endocrinol Metab; 2006 Aug; 291(2):E275-81. PubMed ID: 16492686
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity.
    Campos G; Schmidt-Heck W; Ghallab A; Rochlitz K; Pütter L; Medinas DB; Hetz C; Widera A; Cadenas C; Begher-Tibbe B; Reif R; Günther G; Sachinidis A; Hengstler JG; Godoy P
    Arch Toxicol; 2014 Jun; 88(6):1267-80. PubMed ID: 24748426
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Integration of proteomics, lipidomics, and metabolomics reveals novel metabolic mechanisms underlying N, N-dimethylformamide induced hepatotoxicity.
    Xu L; Zhao Q; Luo J; Ma W; Jin Y; Li C; Hou Y; Feng M; Wang Y; Chen J; Zhao J; Zheng Y; Yu D
    Ecotoxicol Environ Saf; 2020 Dec; 205():111166. PubMed ID: 32827966
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential sensitivity of metabolically competent and non-competent HepaRG cells to apoptosis induced by diclofenac combined or not with TNF-α.
    Al-Attrache H; Sharanek A; Burban A; Burbank M; Gicquel T; Abdel-Razzak Z; Guguen-Guillouzo C; Morel I; Guillouzo A
    Toxicol Lett; 2016 Sep; 258():71-86. PubMed ID: 27313093
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Signal transduction pathways involved in drug-induced liver injury.
    Han D; Shinohara M; Ybanez MD; Saberi B; Kaplowitz N
    Handb Exp Pharmacol; 2010; (196):267-310. PubMed ID: 20020266
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 5-Hydroxymethylfurfural protects against ER stress-induced apoptosis in GalN/TNF-α-injured L02 hepatocytes through regulating the PERK-eIF2α signaling pathway.
    Jiang ZQ; Ma YX; Li MH; Zhan XQ; Zhang X; Wang MY
    Chin J Nat Med; 2015 Dec; 13(12):896-905. PubMed ID: 26721708
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity.
    Van den Hof WF; Van Summeren A; Lommen A; Coonen ML; Brauers K; van Herwijnen M; Wodzig WK; Kleinjans JC
    Toxicology; 2014 Oct; 324():18-26. PubMed ID: 25047351
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.