279 related articles for article (PubMed ID: 28734666)
1. Development of novel LP1-based analogues with enhanced delta opioid receptor profile.
Pasquinucci L; Turnaturi R; Prezzavento O; Arena E; Aricò G; Georgoussi Z; Parenti R; Cantarella G; Parenti C
Bioorg Med Chem; 2017 Sep; 25(17):4745-4752. PubMed ID: 28734666
[TBL] [Abstract][Full Text] [Related]
2. Evaluation of N-substituent structural variations in opioid receptor profile of LP1.
Pasquinucci L; Turnaturi R; Aricò G; Parenti C; Pallaki P; Georgoussi Z; Ronsisvalle S
Bioorg Med Chem; 2016 Jun; 24(12):2832-42. PubMed ID: 27234885
[TBL] [Abstract][Full Text] [Related]
3. The benzomorphan-based LP1 ligand is a suitable MOR/DOR agonist for chronic pain treatment.
Pasquinucci L; Parenti C; Turnaturi R; Aricò G; Marrazzo A; Prezzavento O; Ronsisvalle S; Georgoussi Z; Fourla DD; Scoto GM; Ronsisvalle G
Life Sci; 2012 Jan; 90(1-2):66-70. PubMed ID: 22100511
[TBL] [Abstract][Full Text] [Related]
4. Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand.
Parenti C; Turnaturi R; Aricò G; Marrazzo A; Prezzavento O; Ronsisvalle S; Scoto GM; Ronsisvalle G; Pasquinucci L
Life Sci; 2012 Jun; 90(25-26):957-61. PubMed ID: 22580287
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and Structure-Activity Relationships of LP1 Derivatives: N-Methyl-N-phenylethylamino Analogues as Novel MOR Agonists.
Turnaturi R; Parenti C; Prezzavento O; Marrazzo A; Pallaki P; Georgoussi Z; Amata E; Pasquinucci L
Molecules; 2018 Mar; 23(3):. PubMed ID: 29547588
[TBL] [Abstract][Full Text] [Related]
6. An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain.
Ronsisvalle S; Aricò G; Panarello F; Spadaro A; Pasquinucci L; Pappalardo MS; Parenti C; Ronsisvalle N
Bioorg Med Chem; 2016 Nov; 24(21):5280-5290. PubMed ID: 27624520
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and Structure-Activity Relationships of (-)-
Pasquinucci L; Parenti C; Amata E; Georgoussi Z; Pallaki P; Camarda V; Calò G; Arena E; Montenegro L; Turnaturi R
Pharmaceuticals (Basel); 2018 May; 11(2):. PubMed ID: 29734749
[TBL] [Abstract][Full Text] [Related]
8. Evaluation of N-substitution in 6,7-benzomorphan compounds.
Pasquinucci L; Prezzavento O; Marrazzo A; Amata E; Ronsisvalle S; Georgoussi Z; Fourla DD; Scoto GM; Parenti C; Aricò G; Ronsisvalle G
Bioorg Med Chem; 2010 Jul; 18(14):4975-82. PubMed ID: 20599386
[TBL] [Abstract][Full Text] [Related]
9. Further Optimization and Evaluation of Bioavailable, Mixed-Efficacy μ-Opioid Receptor (MOR) Agonists/δ-Opioid Receptor (DOR) Antagonists: Balancing MOR and DOR Affinities.
Harland AA; Yeomans L; Griggs NW; Anand JP; Pogozheva ID; Jutkiewicz EM; Traynor JR; Mosberg HI
J Med Chem; 2015 Nov; 58(22):8952-69. PubMed ID: 26524472
[TBL] [Abstract][Full Text] [Related]
10. (2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist.
Pasquinucci L; Turnaturi R; Calò G; Pappalardo F; Ferrari F; Russo G; Arena E; Montenegro L; Chiechio S; Prezzavento O; Parenti C
Eur J Med Chem; 2019 Apr; 168():189-198. PubMed ID: 30822708
[TBL] [Abstract][Full Text] [Related]
11. Exploiting the Power of Stereochemistry in Drug Action: 3-[(2
Turnaturi R; Pasquinucci L; Chiechio S; Grasso M; Marrazzo A; Amata E; Dichiara M; Prezzavento O; Parenti C
ACS Chem Neurosci; 2020 Apr; 11(7):999-1005. PubMed ID: 32186844
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, opioid receptor binding, and bioassay of naltrindole analogues substituted in the indolic benzene moiety.
Ananthan S; Johnson CA; Carter RL; Clayton SD; Rice KC; Xu H; Davis P; Porreca F; Rothman RB
J Med Chem; 1998 Jul; 41(15):2872-81. PubMed ID: 9667975
[TBL] [Abstract][Full Text] [Related]
13. The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures.
Parenti C; Turnaturi R; Aricò G; Gramowski-Voss A; Schroeder OH; Marrazzo A; Prezzavento O; Ronsisvalle S; Scoto GM; Ronsisvalle G; Pasquinucci L
Neuropharmacology; 2013 Aug; 71():70-82. PubMed ID: 23541722
[TBL] [Abstract][Full Text] [Related]
14. Analysis of [3H]bremazocine binding in single and combinatorial opioid receptor knockout mice.
Simonin F; Slowe S; Becker JA; Matthes HW; Filliol D; Chluba J; Kitchen I; Kieffer BL
Eur J Pharmacol; 2001 Mar; 414(2-3):189-95. PubMed ID: 11239918
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, in vitro evaluation, and molecular modeling studies of N-substituted benzomorphans, analogs of LP2, as novel MOR ligands.
Costanzo G; Patamia V; Turnaturi R; Parenti C; Zagni C; Lombino J; Amata E; Marrazzo A; Pasquinucci L; Rescifina A
Chem Biol Drug Des; 2023 Jun; 101(6):1382-1392. PubMed ID: 36813756
[TBL] [Abstract][Full Text] [Related]
16. Design, Synthesis, and Structure-Activity Relationship Exploration of Alkyl/Phenylalkyl Piperidine Analogues as Novel Highly Potent and Selective μ Opioid Receptor Agonists.
Huang H; Li X; Guo W; Zhu C; Qian Y; Shen Q; Xu X; Li W; Wang Y; Fu W
ACS Chem Neurosci; 2021 Jan; 12(2):285-299. PubMed ID: 32852933
[TBL] [Abstract][Full Text] [Related]
17. Benzylideneoxymorphone: A new lead for development of bifunctional mu/delta opioid receptor ligands.
Healy JR; Bezawada P; Griggs NW; Devereaux AL; Matsumoto RR; Traynor JR; Coop A; Cunningham CW
Bioorg Med Chem Lett; 2017 Feb; 27(3):666-669. PubMed ID: 28011222
[TBL] [Abstract][Full Text] [Related]
18. Discovery of 3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)-N-phenylpiperidine-1-carboxamide as novel potent analgesic.
Huang H; Wang W; Xu X; Zhu C; Wang Y; Liu J; Li W; Fu W
Eur J Med Chem; 2020 Mar; 189():112070. PubMed ID: 31982651
[TBL] [Abstract][Full Text] [Related]
19. Parallel Synthesis of Hexahydrodiimidazodiazepines Heterocyclic Peptidomimetics and Their in Vitro and in Vivo Activities at μ (MOR), δ (DOR), and κ (KOR) Opioid Receptors.
Eans SO; Ganno ML; Mizrachi E; Houghten RA; Dooley CT; McLaughlin JP; Nefzi A
J Med Chem; 2015 Jun; 58(12):4905-17. PubMed ID: 25996309
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluations of novel endomorphin analogues containing α-hydroxy-β-phenylalanine (AHPBA) displaying mixed μ/δ opioid receptor agonist and δ opioid receptor antagonist activities.
Hu M; Giulianotti MA; McLaughlin JP; Shao J; Debevec G; Maida LE; Geer P; Cazares M; Misler J; Li L; Dooley C; Ganno ML; Eans SO; Mizrachi E; Santos RG; Yongye AB; Houghten RA; Yu Y
Eur J Med Chem; 2015 Mar; 92():270-81. PubMed ID: 25559207
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]