BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 28735867)

  • 1. Cleavage of the Interleukin-11 receptor induces processing of its C-terminal fragments by the gamma-secretase and the proteasome.
    Lokau J; Flynn CM; Garbers C
    Biochem Biophys Res Commun; 2017 Sep; 491(2):296-302. PubMed ID: 28735867
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Proteolytic Cleavage Governs Interleukin-11 Trans-signaling.
    Lokau J; Nitz R; Agthe M; Monhasery N; Aparicio-Siegmund S; Schumacher N; Wolf J; Möller-Hackbarth K; Waetzig GH; Grötzinger J; Müller-Newen G; Rose-John S; Scheller J; Garbers C
    Cell Rep; 2016 Feb; 14(7):1761-1773. PubMed ID: 26876177
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interleukin-11-driven gastric tumourigenesis is independent of trans-signalling.
    Balic JJ; Garbers C; Rose-John S; Yu L; Jenkins BJ
    Cytokine; 2017 Apr; 92():118-123. PubMed ID: 28160627
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cleavage Site Localization Differentially Controls Interleukin-6 Receptor Proteolysis by ADAM10 and ADAM17.
    Riethmueller S; Ehlers JC; Lokau J; Düsterhöft S; Knittler K; Dombrowsky G; Grötzinger J; Rabe B; Rose-John S; Garbers C
    Sci Rep; 2016 May; 6():25550. PubMed ID: 27151651
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interleukin-11 (IL-11) receptor cleavage by the rhomboid protease RHBDL2 induces IL-11 trans-signaling.
    Koch L; Kespohl B; Agthe M; Schumertl T; Düsterhöft S; Lemberg MK; Lokau J; Garbers C
    FASEB J; 2021 Mar; 35(3):e21380. PubMed ID: 33566379
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of proteolysis in interleukin-11 signaling.
    Lokau J; Kespohl B; Kirschke S; Garbers C
    Biochim Biophys Acta Mol Cell Res; 2022 Jan; 1869(1):119135. PubMed ID: 34624437
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling.
    Wolf J; Waetzig GH; Chalaris A; Reinheimer TM; Wege H; Rose-John S; Garbers C
    J Biol Chem; 2016 Jul; 291(31):16186-96. PubMed ID: 27226573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Two N-Linked Glycans Differentially Control Maturation, Trafficking and Proteolysis, but not Activity of the IL-11 Receptor.
    Agthe M; Garbers Y; Grötzinger J; Garbers C
    Cell Physiol Biochem; 2018; 45(5):2071-2085. PubMed ID: 29533934
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genome-wide screen of gamma-secretase-mediated intramembrane cleavage of receptor tyrosine kinases.
    Merilahti JAM; Ojala VK; Knittle AM; Pulliainen AT; Elenius K
    Mol Biol Cell; 2017 Nov; 28(22):3123-3131. PubMed ID: 28904208
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tetraspanin 3: A central endocytic membrane component regulating the expression of ADAM10, presenilin and the amyloid precursor protein.
    Seipold L; Damme M; Prox J; Rabe B; Kasparek P; Sedlacek R; Altmeppen H; Willem M; Boland B; Glatzel M; Saftig P
    Biochim Biophys Acta Mol Cell Res; 2017 Jan; 1864(1):217-230. PubMed ID: 27818272
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interleukin-6-interleukin-11 receptor chimeras reveal ionomycin-induced proteolysis beyond ADAM10.
    Lokau J; Garbers C
    FEBS Lett; 2021 Dec; 595(24):3072-3082. PubMed ID: 34778975
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Coxsackievirus and Adenovirus Receptor (CAR) undergoes ectodomain shedding and regulated intramembrane proteolysis (RIP).
    Houri N; Huang KC; Nalbantoglu J
    PLoS One; 2013; 8(8):e73296. PubMed ID: 24015300
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth.
    Stoeck A; Shang L; Dempsey PJ
    J Cell Sci; 2010 Jul; 123(Pt 13):2319-31. PubMed ID: 20530572
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteolytic cleavage of amyloid precursor protein by ADAM10 mediates proliferation and migration in breast cancer.
    Tsang JYS; Lee MA; Chan TH; Li J; Ni YB; Shao Y; Chan SK; Cheungc SY; Lau KF; Tse GMK
    EBioMedicine; 2018 Dec; 38():89-99. PubMed ID: 30470613
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proteolytic control of Interleukin-11 and Interleukin-6 biology.
    Lokau J; Agthe M; Flynn CM; Garbers C
    Biochim Biophys Acta Mol Cell Res; 2017 Nov; 1864(11 Pt B):2105-2117. PubMed ID: 28630024
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular characterization of the craniosynostosis-associated interleukin-11 receptor variants p.T306_S308dup and p.E364_V368del.
    Kespohl B; Hegele AL; Düsterhöft S; Bakker H; Buettner FFR; Hartig R; Lokau J; Garbers C
    FEBS J; 2024 Apr; 291(8):1667-1683. PubMed ID: 37994264
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases.
    Garbers C; Monhasery N; Aparicio-Siegmund S; Lokau J; Baran P; Nowell MA; Jones SA; Rose-John S; Scheller J
    Biochim Biophys Acta; 2014 Sep; 1842(9):1485-94. PubMed ID: 24878322
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of ADAM10 in intestinal crypt homeostasis and tumorigenesis.
    Dempsey PJ
    Biochim Biophys Acta Mol Cell Res; 2017 Nov; 1864(11 Pt B):2228-2239. PubMed ID: 28739265
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differences in Shedding of the Interleukin-11 Receptor by the Proteases ADAM9, ADAM10, ADAM17, Meprin α, Meprin β and MT1-MMP.
    Sammel M; Peters F; Lokau J; Scharfenberg F; Werny L; Linder S; Garbers C; Rose-John S; Becker-Pauly C
    Int J Mol Sci; 2019 Jul; 20(15):. PubMed ID: 31357561
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Posttranslational proteolytic processing of Leda-1/Pianp involves cleavage by MMPs, ADAM10/17 and gamma-secretase.
    Biswas S; Adrian M; Weber J; Evdokimov K; Winkler M; Géraud C
    Biochem Biophys Res Commun; 2016 Sep; 477(4):661-666. PubMed ID: 27349870
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.