185 related articles for article (PubMed ID: 28739292)
1. A polar SxxS motif drives assembly of the transmembrane domains of Toll-like receptor 4.
Kargas V; Marzinek JK; Holdbrook DA; Yin H; Ford RC; Bond PJ
Biochim Biophys Acta Biomembr; 2017 Oct; 1859(10):2086-2095. PubMed ID: 28739292
[TBL] [Abstract][Full Text] [Related]
2. Structural insights into pharmacophore-assisted in silico identification of protein-protein interaction inhibitors for inhibition of human toll-like receptor 4 - myeloid differentiation factor-2 (hTLR4-MD-2) complex.
Mishra V; Pathak C
J Biomol Struct Dyn; 2019 May; 37(8):1968-1991. PubMed ID: 29842849
[TBL] [Abstract][Full Text] [Related]
3. A Thermodynamic Funnel Drives Bacterial Lipopolysaccharide Transfer in the TLR4 Pathway.
Huber RG; Berglund NA; Kargas V; Marzinek JK; Holdbrook DA; Khalid S; Piggot TJ; Schmidtchen A; Bond PJ
Structure; 2018 Aug; 26(8):1151-1161.e4. PubMed ID: 29779787
[TBL] [Abstract][Full Text] [Related]
4. Full-Atom Model of the Agonist LPS-Bound Toll-like Receptor 4 Dimer in a Membrane Environment.
Matamoros-Recio A; Franco-Gonzalez JF; Perez-Regidor L; Billod JM; Guzman-Caldentey J; Martin-Santamaria S
Chemistry; 2021 Nov; 27(62):15406-15425. PubMed ID: 34569111
[TBL] [Abstract][Full Text] [Related]
5. Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells.
Tsukamoto H; Fukudome K; Takao S; Tsuneyoshi N; Kimoto M
Int Immunol; 2010 Apr; 22(4):271-80. PubMed ID: 20133493
[TBL] [Abstract][Full Text] [Related]
6. Molecular dynamics simulations of the dimerization of transmembrane alpha-helices.
Psachoulia E; Marshall DP; Sansom MS
Acc Chem Res; 2010 Mar; 43(3):388-96. PubMed ID: 20017540
[TBL] [Abstract][Full Text] [Related]
7. Evidence for ProTα-TLR4/MD-2 binding: molecular dynamics and gravimetric assay studies.
Omotuyi O; Matsunaga H; Ueda H
Expert Opin Biol Ther; 2015; 15 Suppl 1():S223-9. PubMed ID: 25604147
[TBL] [Abstract][Full Text] [Related]
8. Different functional role of domain boundaries of Toll-like receptor 4.
Treeby M; Vasl J; Ota P; Friedrich J; Jerala R
Biochem Biophys Res Commun; 2009 Mar; 381(1):65-9. PubMed ID: 19351596
[TBL] [Abstract][Full Text] [Related]
9. Contributions of unique intracellular domains to switchlike biosensing by Toll-like receptor 4.
Daringer NM; Schwarz KA; Leonard JN
J Biol Chem; 2015 Apr; 290(14):8764-77. PubMed ID: 25694428
[TBL] [Abstract][Full Text] [Related]
10. Computational Insight Into the Structural Organization of Full-Length Toll-Like Receptor 4 Dimer in a Model Phospholipid Bilayer.
Patra MC; Kwon HK; Batool M; Choi S
Front Immunol; 2018; 9():489. PubMed ID: 29593733
[TBL] [Abstract][Full Text] [Related]
11. Mechanism of bacterial interference with TLR4 signaling by Brucella Toll/interleukin-1 receptor domain-containing protein TcpB.
Alaidarous M; Ve T; Casey LW; Valkov E; Ericsson DJ; Ullah MO; Schembri MA; Mansell A; Sweet MJ; Kobe B
J Biol Chem; 2014 Jan; 289(2):654-68. PubMed ID: 24265315
[TBL] [Abstract][Full Text] [Related]
12. The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation.
Panter G; Jerala R
J Biol Chem; 2011 Jul; 286(26):23334-44. PubMed ID: 21543336
[TBL] [Abstract][Full Text] [Related]
13. Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner.
Wong SW; Kwon MJ; Choi AM; Kim HP; Nakahira K; Hwang DH
J Biol Chem; 2009 Oct; 284(40):27384-92. PubMed ID: 19648648
[TBL] [Abstract][Full Text] [Related]
14. The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane.
Tanimura N; Saitoh S; Ohto U; Akashi-Takamura S; Fujimoto Y; Fukase K; Shimizu T; Miyake K
Int Immunol; 2014 Jun; 26(6):307-14. PubMed ID: 24380872
[TBL] [Abstract][Full Text] [Related]
15. The role of protein-protein interactions in Toll-like receptor function.
Berglund NA; Kargas V; Ortiz-Suarez ML; Bond PJ
Prog Biophys Mol Biol; 2015 Oct; 119(1):72-83. PubMed ID: 26144017
[TBL] [Abstract][Full Text] [Related]
16. Structures of the toll-like receptor family and its ligand complexes.
Jin MS; Lee JO
Immunity; 2008 Aug; 29(2):182-91. PubMed ID: 18701082
[TBL] [Abstract][Full Text] [Related]
17. Investigating the effect of key mutations on the conformational dynamics of toll-like receptor dimers through molecular dynamics simulations and protein structure networks.
Mahita J; Sowdhamini R
Proteins; 2018 Apr; 86(4):475-490. PubMed ID: 29383743
[TBL] [Abstract][Full Text] [Related]
18. Quantitative single-molecule imaging of TLR4 reveals ligand-specific receptor dimerization.
Krüger CL; Zeuner MT; Cottrell GS; Widera D; Heilemann M
Sci Signal; 2017 Oct; 10(503):. PubMed ID: 29089449
[TBL] [Abstract][Full Text] [Related]
19. The structural basis for endotoxin-induced allosteric regulation of the Toll-like receptor 4 (TLR4) innate immune receptor.
Paramo T; Piggot TJ; Bryant CE; Bond PJ
J Biol Chem; 2013 Dec; 288(51):36215-25. PubMed ID: 24178299
[TBL] [Abstract][Full Text] [Related]
20. Computational Approaches to Toll-Like Receptor 4 Modulation.
Billod JM; Lacetera A; Guzmán-Caldentey J; Martín-Santamaría S
Molecules; 2016 Jul; 21(8):. PubMed ID: 27483231
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
