457 related articles for article (PubMed ID: 28743452)
1. Transcriptional profiles for distinct aggregation states of mutant Huntingtin exon 1 protein unmask new Huntington's disease pathways.
Moily NS; Ormsby AR; Stojilovic A; Ramdzan YM; Diesch J; Hannan RD; Zajac MS; Hannan AJ; Oshlack A; Hatters DM
Mol Cell Neurosci; 2017 Sep; 83():103-112. PubMed ID: 28743452
[TBL] [Abstract][Full Text] [Related]
2. Amplification of neurotoxic HTTex1 assemblies in human neurons.
Chongtham A; Isas JM; Pandey NK; Rawat A; Yoo JH; Mastro T; Kennedy MB; Langen R; Khoshnan A
Neurobiol Dis; 2021 Nov; 159():105517. PubMed ID: 34563643
[TBL] [Abstract][Full Text] [Related]
3. Aggregation landscapes of Huntingtin exon 1 protein fragments and the critical repeat length for the onset of Huntington's disease.
Chen M; Wolynes PG
Proc Natl Acad Sci U S A; 2017 Apr; 114(17):4406-4411. PubMed ID: 28400517
[TBL] [Abstract][Full Text] [Related]
4. Spontaneous self-assembly of pathogenic huntingtin exon 1 protein into amyloid structures.
Trepte P; Strempel N; Wanker EE
Essays Biochem; 2014; 56():167-80. PubMed ID: 25131594
[TBL] [Abstract][Full Text] [Related]
5. Copper enhances aggregational toxicity of mutant huntingtin in a Drosophila model of Huntington's Disease.
Lobato AG; Ortiz-Vega N; Zhu Y; Neupane D; Meier KK; Zhai RG
Biochim Biophys Acta Mol Basis Dis; 2024 Jan; 1870(1):166928. PubMed ID: 38660915
[TBL] [Abstract][Full Text] [Related]
6. The pathobiology of perturbed mutant huntingtin protein-protein interactions in Huntington's disease.
Wanker EE; Ast A; Schindler F; Trepte P; Schnoegl S
J Neurochem; 2019 Nov; 151(4):507-519. PubMed ID: 31418858
[TBL] [Abstract][Full Text] [Related]
7. Modulation of mutant Huntingtin aggregates and toxicity by human myeloid leukemia factors.
Banerjee M; Datta M; Bhattacharyya NP
Int J Biochem Cell Biol; 2017 Jan; 82():1-9. PubMed ID: 27840155
[TBL] [Abstract][Full Text] [Related]
8. HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington's disease mice.
Chen L; Qin Y; Guo T; Zhu W; Lin J; Xing T; Duan X; Zhang Y; Ruan E; Li X; Yin P; Li S; Li XJ; Yang S
Cell Death Dis; 2024 May; 15(5):337. PubMed ID: 38744826
[TBL] [Abstract][Full Text] [Related]
9. N-Terminal Fragments of Huntingtin Longer than Residue 170 form Visible Aggregates Independently to Polyglutamine Expansion.
Chen MZ; Mok SA; Ormsby AR; Muchowski PJ; Hatters DM
J Huntingtons Dis; 2017; 6(1):79-91. PubMed ID: 28339398
[TBL] [Abstract][Full Text] [Related]
10. Conformational dynamics and self-association of intrinsically disordered Huntingtin exon 1 in cells.
Büning S; Sharma A; Vachharajani S; Newcombe E; Ormsby A; Gao M; Gnutt D; Vöpel T; Hatters DM; Ebbinghaus S
Phys Chem Chem Phys; 2017 May; 19(17):10738-10747. PubMed ID: 28094373
[TBL] [Abstract][Full Text] [Related]
11. Formation and Structure of Wild Type Huntingtin Exon-1 Fibrils.
Isas JM; Langen A; Isas MC; Pandey NK; Siemer AB
Biochemistry; 2017 Jul; 56(28):3579-3586. PubMed ID: 28621522
[TBL] [Abstract][Full Text] [Related]
12. Protein phosphatase 1 regulates huntingtin exon 1 aggregation and toxicity.
Branco-Santos J; Herrera F; Poças GM; Pires-Afonso Y; Giorgini F; Domingos PM; Outeiro TF
Hum Mol Genet; 2017 Oct; 26(19):3763-3775. PubMed ID: 28934390
[TBL] [Abstract][Full Text] [Related]
13. The dynamics of early-state transcriptional changes and aggregate formation in a Huntington's disease cell model.
van Hagen M; Piebes DGE; de Leeuw WC; Vuist IM; van Roon-Mom WMC; Moerland PD; Verschure PJ
BMC Genomics; 2017 May; 18(1):373. PubMed ID: 28499347
[TBL] [Abstract][Full Text] [Related]
14. Nucleic Acid Therapeutics in Huntington's Disease.
Singh K; Roy I
Recent Pat Biotechnol; 2019; 13(3):187-206. PubMed ID: 30747088
[TBL] [Abstract][Full Text] [Related]
15. Osmolytes dynamically regulate mutant Huntingtin aggregation and CREB function in Huntington's disease cell models.
Aravindan S; Chen S; Choudhry H; Molfetta C; Chen KY; Liu AYC
Sci Rep; 2020 Sep; 10(1):15511. PubMed ID: 32968182
[TBL] [Abstract][Full Text] [Related]
16. Identification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearance.
Martin DDO; Schmidt ME; Nguyen YT; Lazic N; Hayden MR
FASEB J; 2019 Mar; 33(3):3190-3197. PubMed ID: 30423259
[TBL] [Abstract][Full Text] [Related]
17. Meso scale discovery-based assays for the detection of aggregated huntingtin.
Reindl W; Baldo B; Schulz J; Janack I; Lindner I; Kleinschmidt M; Sedaghat Y; Thiede C; Tillack K; Schmidt C; Cardaun I; Schwagarus T; Herrmann F; Hotze M; Osborne GF; Herrmann S; Weiss A; Zerbinatti C; Bates GP; Bard J; Munoz-Sanjuan I; Macdonald D
PLoS One; 2019; 14(3):e0213521. PubMed ID: 30913220
[TBL] [Abstract][Full Text] [Related]
18. Beta catenin is regulated by its subcellular distribution and mutant huntingtin status in Huntington's disease cell STHdhQ111/HdhQ111.
Ghatak S; Raha S
Biochem Biophys Res Commun; 2018 Sep; 503(1):359-364. PubMed ID: 29894684
[TBL] [Abstract][Full Text] [Related]
19. Binding, internalization and fate of Huntingtin Exon1 fibrillar assemblies in mitotic and nonmitotic neuroblastoma cells.
Ruiz-Arlandis G; Pieri L; Bousset L; Melki R
Neuropathol Appl Neurobiol; 2016 Feb; 42(2):137-52. PubMed ID: 26111612
[TBL] [Abstract][Full Text] [Related]
20. Polyglutamine tracts regulate beclin 1-dependent autophagy.
Ashkenazi A; Bento CF; Ricketts T; Vicinanza M; Siddiqi F; Pavel M; Squitieri F; Hardenberg MC; Imarisio S; Menzies FM; Rubinsztein DC
Nature; 2017 May; 545(7652):108-111. PubMed ID: 28445460
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]