385 related articles for article (PubMed ID: 28747530)
1. Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies.
Hwang JK; Wang C; Du Z; Meyers RM; Kepler TB; Neuberg D; Kwong PD; Mascola JR; Joyce MG; Bonsignori M; Haynes BF; Yeap LS; Alt FW
Proc Natl Acad Sci U S A; 2017 Aug; 114(32):8614-8619. PubMed ID: 28747530
[TBL] [Abstract][Full Text] [Related]
2. Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth.
Chen X; Zhou T; Schmidt SD; Duan H; Cheng C; Chuang GY; Gu Y; Louder MK; Lin BC; Shen CH; Sheng Z; Zheng MX; Doria-Rose NA; Joyce MG; Shapiro L; Tian M; Alt FW; Kwong PD; Mascola JR
Immunity; 2021 Feb; 54(2):324-339.e8. PubMed ID: 33453152
[TBL] [Abstract][Full Text] [Related]
3. Humanized V(D)J-rearranging and TdT-expressing mouse vaccine models with physiological HIV-1 broadly neutralizing antibody precursors.
Luo S; Jing C; Ye AY; Kratochvil S; Cottrell CA; Koo JH; Chapdelaine Williams A; Francisco LV; Batra H; Lamperti E; Kalyuzhniy O; Zhang Y; Barbieri A; Manis JP; Haynes BF; Schief WR; Batista FD; Tian M; Alt FW
Proc Natl Acad Sci U S A; 2023 Jan; 120(1):e2217883120. PubMed ID: 36574685
[TBL] [Abstract][Full Text] [Related]
4. Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies.
Kepler TB; Liao HX; Alam SM; Bhaskarabhatla R; Zhang R; Yandava C; Stewart S; Anasti K; Kelsoe G; Parks R; Lloyd KE; Stolarchuk C; Pritchett J; Solomon E; Friberg E; Morris L; Karim SS; Cohen MS; Walter E; Moody MA; Wu X; Altae-Tran HR; Georgiev IS; Kwong PD; Boyd SD; Fire AZ; Mascola JR; Haynes BF
Cell Host Microbe; 2014 Sep; 16(3):304-13. PubMed ID: 25211073
[TBL] [Abstract][Full Text] [Related]
5. Diverse pathways of escape from all well-characterized VRC01-class broadly neutralizing HIV-1 antibodies.
Otsuka Y; Schmitt K; Quinlan BD; Gardner MR; Alfant B; Reich A; Farzan M; Choe H
PLoS Pathog; 2018 Aug; 14(8):e1007238. PubMed ID: 30125330
[TBL] [Abstract][Full Text] [Related]
6. HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization.
Navis M; Tran K; Bale S; Phad GE; Guenaga J; Wilson R; Soldemo M; McKee K; Sundling C; Mascola J; Li Y; Wyatt RT; Karlsson Hedestam GB
PLoS Pathog; 2014 Aug; 10(8):e1004337. PubMed ID: 25166308
[TBL] [Abstract][Full Text] [Related]
7. HIV-1 Neutralizing Antibodies with Limited Hypermutation from an Infant.
Simonich CA; Williams KL; Verkerke HP; Williams JA; Nduati R; Lee KK; Overbaugh J
Cell; 2016 Jun; 166(1):77-87. PubMed ID: 27345369
[TBL] [Abstract][Full Text] [Related]
8. A single mutation turns a non-binding germline-like predecessor of broadly neutralizing antibody into a binding antibody to HIV-1 envelope glycoproteins.
Yuan T; Li J; Zhang MY
MAbs; 2011; 3(4):402-7. PubMed ID: 21540646
[TBL] [Abstract][Full Text] [Related]
9. Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies.
Briney B; Sok D; Jardine JG; Kulp DW; Skog P; Menis S; Jacak R; Kalyuzhniy O; de Val N; Sesterhenn F; Le KM; Ramos A; Jones M; Saye-Francisco KL; Blane TR; Spencer S; Georgeson E; Hu X; Ozorowski G; Adachi Y; Kubitz M; Sarkar A; Wilson IA; Ward AB; Nemazee D; Burton DR; Schief WR
Cell; 2016 Sep; 166(6):1459-1470.e11. PubMed ID: 27610570
[TBL] [Abstract][Full Text] [Related]
10. Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection.
Sheng Z; Schramm CA; Connors M; Morris L; Mascola JR; Kwong PD; Shapiro L
PLoS Comput Biol; 2016 May; 12(5):e1004940. PubMed ID: 27191167
[TBL] [Abstract][Full Text] [Related]
11. Human Ig knockin mice to study the development and regulation of HIV-1 broadly neutralizing antibodies.
Verkoczy L; Alt FW; Tian M
Immunol Rev; 2017 Jan; 275(1):89-107. PubMed ID: 28133799
[TBL] [Abstract][Full Text] [Related]
12. HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen.
Jardine JG; Ota T; Sok D; Pauthner M; Kulp DW; Kalyuzhniy O; Skog PD; Thinnes TC; Bhullar D; Briney B; Menis S; Jones M; Kubitz M; Spencer S; Adachi Y; Burton DR; Schief WR; Nemazee D
Science; 2015 Jul; 349(6244):156-61. PubMed ID: 26089355
[TBL] [Abstract][Full Text] [Related]
13. Complementary Roles of Antibody Heavy and Light Chain Somatic Hypermutation in Conferring Breadth and Potency to the HIV-1-Specific CAP256-VRC26 bNAb Lineage.
Sacks D; Wiehe K; Morris L; Moore PL
J Virol; 2022 May; 96(10):e0027022. PubMed ID: 35510865
[TBL] [Abstract][Full Text] [Related]
14. Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier.
Bonsignori M; Scott E; Wiehe K; Easterhoff D; Alam SM; Hwang KK; Cooper M; Xia SM; Zhang R; Montefiori DC; Henderson R; Nie X; Kelsoe G; Moody MA; Chen X; Joyce MG; Kwong PD; Connors M; Mascola JR; McGuire AT; Stamatatos L; Medina-Ramírez M; Sanders RW; Saunders KO; Kepler TB; Haynes BF
Immunity; 2018 Dec; 49(6):1162-1174.e8. PubMed ID: 30552024
[TBL] [Abstract][Full Text] [Related]
15. Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.
Jardine JG; Sok D; Julien JP; Briney B; Sarkar A; Liang CH; Scherer EA; Henry Dunand CJ; Adachi Y; Diwanji D; Hsueh J; Jones M; Kalyuzhniy O; Kubitz M; Spencer S; Pauthner M; Saye-Francisco KL; Sesterhenn F; Wilson PC; Galloway DM; Stanfield RL; Wilson IA; Burton DR; Schief WR
PLoS Pathog; 2016 Aug; 12(8):e1005815. PubMed ID: 27560183
[TBL] [Abstract][Full Text] [Related]
16. Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes.
Yeap LS; Hwang JK; Du Z; Meyers RM; Meng FL; Jakubauskaitė A; Liu M; Mani V; Neuberg D; Kepler TB; Wang JH; Alt FW
Cell; 2015 Nov; 163(5):1124-1137. PubMed ID: 26582132
[TBL] [Abstract][Full Text] [Related]
17. Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies.
Davenport TM; Gorman J; Joyce MG; Zhou T; Soto C; Guttman M; Moquin S; Yang Y; Zhang B; Doria-Rose NA; Hu SL; Mascola JR; Kwong PD; Lee KK
Structure; 2016 Aug; 24(8):1346-1357. PubMed ID: 27477385
[TBL] [Abstract][Full Text] [Related]
18. Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection.
Chan KW; Pan R; Costa M; Gorny MK; Wang S; Lu S; Kong XP
J Virol; 2018 Sep; 92(18):. PubMed ID: 29997214
[TBL] [Abstract][Full Text] [Related]
19. B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models.
Huang D; Abbott RK; Havenar-Daughton C; Skog PD; Al-Kolla R; Groschel B; Blane TR; Menis S; Tran JT; Thinnes TC; Volpi SA; Liguori A; Schiffner T; Villegas SM; Kalyuzhniy O; Pintea M; Voss JE; Phelps N; Tingle R; Rodriguez AR; Martin G; Kupryianov S; deCamp A; Schief WR; Nemazee D; Crotty S
Proc Natl Acad Sci U S A; 2020 Sep; 117(37):22920-22931. PubMed ID: 32873644
[TBL] [Abstract][Full Text] [Related]
20. Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Kong L; Ju B; Chen Y; He L; Ren L; Liu J; Hong K; Su B; Wang Z; Ozorowski G; Ji X; Hua Y; Chen Y; Deller MC; Hao Y; Feng Y; Garces F; Wilson R; Dai K; O'Dell S; McKee K; Mascola JR; Ward AB; Wyatt RT; Li Y; Wilson IA; Zhu J; Shao Y
Immunity; 2016 Apr; 44(4):939-50. PubMed ID: 27067056
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
