These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 28749250)

  • 1. Discovery of thalicthuberine as a novel antimitotic agent from nature that disrupts microtubule dynamics and induces apoptosis in prostate cancer cells.
    Levrier C; Rockstroh A; Gabrielli B; Kavallaris M; Lehman M; Davis RA; Sadowski MC; Nelson CC
    Cell Cycle; 2018; 17(5):652-668. PubMed ID: 28749250
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells.
    Levrier C; Sadowski MC; Rockstroh A; Gabrielli B; Kavallaris M; Lehman M; Davis RA; Nelson CC
    Mol Cancer Ther; 2017 Jan; 16(1):3-15. PubMed ID: 27760837
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth.
    Jordan MA; Kamath K; Manna T; Okouneva T; Miller HP; Davis C; Littlefield BA; Wilson L
    Mol Cancer Ther; 2005 Jul; 4(7):1086-95. PubMed ID: 16020666
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-Phenyl-5-(pyrrolidin-1-yl)-1-(3,4,5-trimethoxybenzyl)-1H-benzimidazole, a benzimidazole derivative, inhibits growth of human prostate cancer cells by affecting tubulin and c-Jun N-terminal kinase.
    Chang WL; Chang CS; Chiang PC; Ho YF; Liu JF; Chang KW; Guh JH
    Br J Pharmacol; 2010 Aug; 160(7):1677-89. PubMed ID: 20649571
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells.
    Dinić J; Ríos-Luci C; Karpaviciene I; Cikotiene I; Fernandes MX; Pešić M; Padrón JM
    Invest New Drugs; 2020 Jun; 38(3):584-598. PubMed ID: 31177401
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Indirubin, a bis-indole alkaloid binds to tubulin and exhibits antimitotic activity against HeLa cells in synergism with vinblastine.
    Mohan L; Raghav D; Ashraf SM; Sebastian J; Rathinasamy K
    Biomed Pharmacother; 2018 Sep; 105():506-517. PubMed ID: 29883946
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The small molecule inhibitor YK-4-279 disrupts mitotic progression of neuroblastoma cells, overcomes drug resistance and synergizes with inhibitors of mitosis.
    Kollareddy M; Sherrard A; Park JH; Szemes M; Gallacher K; Melegh Z; Oltean S; Michaelis M; Cinatl J; Kaidi A; Malik K
    Cancer Lett; 2017 Sep; 403():74-85. PubMed ID: 28602975
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An antimitotic and antivascular agent BPR0L075 overcomes multidrug resistance and induces mitotic catastrophe in paclitaxel-resistant ovarian cancer cells.
    Wang X; Wu E; Wu J; Wang TL; Hsieh HP; Liu X
    PLoS One; 2013; 8(6):e65686. PubMed ID: 23762410
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CWF-145, a novel synthetic quinolone derivative exerts potent antimitotic activity against human prostate cancer: Rapamycin enhances antimitotic drug-induced apoptosis through the inhibition of Akt/mTOR pathway.
    Hung CM; Lin YC; Liu LC; Kuo SC; Ho CT; Way TD
    Chem Biol Interact; 2016 Dec; 260():1-12. PubMed ID: 27769712
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules.
    Zhang Z; Meng T; He J; Li M; Tong LJ; Xiong B; Lin L; Shen J; Miao ZH; Ding J
    Invest New Drugs; 2010 Dec; 28(6):715-28. PubMed ID: 19705064
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
    Kamath K; Okouneva T; Larson G; Panda D; Wilson L; Jordan MA
    Mol Cancer Ther; 2006 Sep; 5(9):2225-33. PubMed ID: 16985056
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nakiterpiosin targets tubulin and triggers mitotic catastrophe in human cancer cells.
    Wei JH; Seemann J
    Mol Cancer Ther; 2010 Dec; 9(12):3375-85. PubMed ID: 21139045
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antimitotic effect of the retinoid 4-oxo-fenretinide through inhibition of tubulin polymerization: a novel mechanism of retinoid growth-inhibitory activity.
    Appierto V; Tiberio P; Cavadini E; Casalini P; Cappelletti G; Formelli F
    Mol Cancer Ther; 2009 Dec; 8(12):3360-8. PubMed ID: 19996280
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NMK-BH2, a novel microtubule-depolymerising bis (indolyl)-hydrazide-hydrazone, induces apoptotic and autophagic cell death in cervical cancer cells by binding to tubulin at colchicine - site.
    Das Mukherjee D; Kumar NM; Tantak MP; Datta S; Ghosh Dastidar D; Kumar D; Chakrabarti G
    Biochim Biophys Acta Mol Cell Res; 2020 Oct; 1867(10):118762. PubMed ID: 32502617
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective Inhibition of Spindle Microtubules by a Tubulin-Binding Quinazoline Derivative.
    Sawada JI; Ishii H; Matsuno K; Sato M; Suzuki Y; Asai A
    Mol Pharmacol; 2019 Nov; 96(5):609-618. PubMed ID: 31471455
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin.
    Kuznetsov G; TenDyke K; Towle MJ; Cheng H; Liu J; Marsh JP; Schiller SE; Spyvee MR; Yang H; Seletsky BM; Shaffer CJ; Marceau V; Yao Y; Suh EM; Campagna S; Fang FG; Kowalczyk JJ; Littlefield BA
    Mol Cancer Ther; 2009 Oct; 8(10):2852-60. PubMed ID: 19825803
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel synthetic 1,3-phenyl bis-thiourea compound targets microtubule polymerization to cause cancer cell death.
    Shing JC; Choi JW; Chapman R; Schroeder MA; Sarkaria JN; Fauq A; Bram RJ
    Cancer Biol Ther; 2014 Jul; 15(7):895-905. PubMed ID: 24755487
    [TBL] [Abstract][Full Text] [Related]  

  • 18. YAN, a novel microtubule inhibitor, inhibits P-gp and MRP1 function and induces mitotic slippage followed by apoptosis in multidrug-resistant A549/Taxol cells.
    Gao M; Liu T; Li J; Guan Q; Wang H; Yan S; Li Z; Zuo D; Zhang W; Wu Y
    Toxicol In Vitro; 2020 Dec; 69():104971. PubMed ID: 32805372
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Microtubule dynamics, mitotic arrest, and apoptosis: drug-induced differential effects of betaIII-tubulin.
    Gan PP; McCarroll JA; Po'uha ST; Kamath K; Jordan MA; Kavallaris M
    Mol Cancer Ther; 2010 May; 9(5):1339-48. PubMed ID: 20442307
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Arsenic trioxide produces polymerization of microtubules and mitotic arrest before apoptosis in human tumor cell lines.
    Ling YH; Jiang JD; Holland JF; Perez-Soler R
    Mol Pharmacol; 2002 Sep; 62(3):529-38. PubMed ID: 12181429
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.