BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

546 related articles for article (PubMed ID: 28752047)

  • 1. Amyloid formation disrupts the balance between interleukin-1β and interleukin-1 receptor antagonist in human islets.
    Hui Q; Asadi A; Park YJ; Kieffer TJ; Ao Z; Warnock GL; Marzban L
    Mol Metab; 2017 Aug; 6(8):833-844. PubMed ID: 28752047
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual role of interleukin-1β in islet amyloid formation and its β-cell toxicity: Implications for type 2 diabetes and islet transplantation.
    Park YJ; Warnock GL; Ao Z; Safikhan N; Meloche M; Asadi A; Kieffer TJ; Marzban L
    Diabetes Obes Metab; 2017 May; 19(5):682-694. PubMed ID: 28058779
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyloid formation reduces protein kinase B phosphorylation in primary islet β-cells which is improved by blocking IL-1β signaling.
    Zhang Y; Warnock GL; Ao Z; Park YJ; Safikhan N; Ghahary A; Marzban L
    PLoS One; 2018; 13(2):e0193184. PubMed ID: 29474443
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of caspase-8 in amyloid-induced beta cell death in human and mouse islets.
    Park YJ; Woo M; Kieffer TJ; Hakem R; Safikhan N; Yang F; Ao Z; Warnock GL; Marzban L
    Diabetologia; 2014 Apr; 57(4):765-75. PubMed ID: 24442508
    [TBL] [Abstract][Full Text] [Related]  

  • 5. IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice.
    Westwell-Roper CY; Chehroudi CA; Denroche HC; Courtade JA; Ehses JA; Verchere CB
    Diabetologia; 2015 Mar; 58(3):575-85. PubMed ID: 25491100
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro.
    Templin AT; Mellati M; Meier DT; Esser N; Hogan MF; Castillo JJ; Akter R; Raleigh DP; Zraika S; Hull RL; Kahn SE
    Diabetologia; 2020 Nov; 63(11):2385-2395. PubMed ID: 32728889
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide.
    Park YJ; Lee S; Kieffer TJ; Warnock GL; Safikhan N; Speck M; Hao Z; Woo M; Marzban L
    Diabetologia; 2012 Feb; ():. PubMed ID: 22301943
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3.
    Law E; Lu S; Kieffer TJ; Warnock GL; Ao Z; Woo M; Marzban L
    Diabetologia; 2010 Jul; 53(7):1415-27. PubMed ID: 20369225
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alpha1-antitrypsin ameliorates islet amyloid-induced glucose intolerance and β-cell dysfunction.
    Rodríguez-Comas J; Moreno-Vedia J; Obach M; Castaño C; de Pablo S; Alcarraz-Vizán G; Díaz-Catalán D; Mestre A; Horrillo R; Costa M; Novials A; Servitja JM
    Mol Metab; 2020 Jul; 37():100984. PubMed ID: 32229246
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Resident macrophages mediate islet amyloid polypeptide-induced islet IL-1β production and β-cell dysfunction.
    Westwell-Roper CY; Ehses JA; Verchere CB
    Diabetes; 2014 May; 63(5):1698-711. PubMed ID: 24222351
    [TBL] [Abstract][Full Text] [Related]  

  • 11. β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion.
    Böni-Schnetzler M; Häuselmann SP; Dalmas E; Meier DT; Thienel C; Traub S; Schulze F; Steiger L; Dror E; Martin P; Herrera PL; Gabay C; Donath MY
    Cell Rep; 2018 Feb; 22(7):1774-1786. PubMed ID: 29444430
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.
    Westwell-Roper C; Dai DL; Soukhatcheva G; Potter KJ; van Rooijen N; Ehses JA; Verchere CB
    J Immunol; 2011 Sep; 187(5):2755-65. PubMed ID: 21813778
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?
    Welsh N; Cnop M; Kharroubi I; Bugliani M; Lupi R; Marchetti P; Eizirik DL
    Diabetes; 2005 Nov; 54(11):3238-44. PubMed ID: 16249450
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets.
    Maedler K; Sergeev P; Ehses JA; Mathe Z; Bosco D; Berney T; Dayer JM; Reinecke M; Halban PA; Donath MY
    Proc Natl Acad Sci U S A; 2004 May; 101(21):8138-43. PubMed ID: 15141093
    [TBL] [Abstract][Full Text] [Related]  

  • 15. cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets.
    Subramanian SL; Hull RL; Zraika S; Aston-Mourney K; Udayasankar J; Kahn SE
    Diabetologia; 2012 Jan; 55(1):166-74. PubMed ID: 22038516
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Three-dimensional scaffolds reduce islet amyloid formation and enhance survival and function of cultured human islets.
    Zhang Y; Jalili RB; Warnock GL; Ao Z; Marzban L; Ghahary A
    Am J Pathol; 2012 Oct; 181(4):1296-305. PubMed ID: 22902430
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The glucagon-like peptide-1 receptor agonist exenatide restores impaired pro-islet amyloid polypeptide processing in cultured human islets: implications in type 2 diabetes and islet transplantation.
    Park YJ; Ao Z; Kieffer TJ; Chen H; Safikhan N; Thompson DM; Meloche M; Warnock GL; Marzban L
    Diabetologia; 2013 Mar; 56(3):508-19. PubMed ID: 23262664
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets.
    Maedler K; Schumann DM; Sauter N; Ellingsgaard H; Bosco D; Baertschiger R; Iwakura Y; Oberholzer J; Wollheim CB; Gauthier BR; Donath MY
    Diabetes; 2006 Oct; 55(10):2713-22. PubMed ID: 17003335
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1beta-induced beta-cell impairment and activation of islet cell apoptosis in vitro.
    Giannoukakis N; Rudert WA; Ghivizzani SC; Gambotto A; Ricordi C; Trucco M; Robbins PD
    Diabetes; 1999 Sep; 48(9):1730-6. PubMed ID: 10480601
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of mitochondrial apoptotic pathway in islet amyloid-induced β-cell death.
    Wong HY; Hui Q; Hao Z; Warnock GL; Woo M; Luciani DS; Marzban L
    Mol Cell Endocrinol; 2021 Nov; 537():111424. PubMed ID: 34400259
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.