249 related articles for article (PubMed ID: 28753207)
1. The proline rich domain of p53 is dispensable for MGMT-dependent DNA repair and cell survival following alkylation damage.
Baran K; Yang M; Dillon CP; Samson LL; Green DR
Cell Death Differ; 2017 Nov; 24(11):1925-1936. PubMed ID: 28753207
[TBL] [Abstract][Full Text] [Related]
2. p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents.
Grombacher T; Eichhorn U; Kaina B
Oncogene; 1998 Aug; 17(7):845-51. PubMed ID: 9780001
[TBL] [Abstract][Full Text] [Related]
3. O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.
Hermisson M; Klumpp A; Wick W; Wischhusen J; Nagel G; Roos W; Kaina B; Weller M
J Neurochem; 2006 Feb; 96(3):766-76. PubMed ID: 16405512
[TBL] [Abstract][Full Text] [Related]
4. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.
Kaina B; Christmann M; Naumann S; Roos WP
DNA Repair (Amst); 2007 Aug; 6(8):1079-99. PubMed ID: 17485253
[TBL] [Abstract][Full Text] [Related]
5. Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents.
Cai S; Xu Y; Cooper RJ; Ferkowicz MJ; Hartwell JR; Pollok KE; Kelley MR
Cancer Res; 2005 Apr; 65(8):3319-27. PubMed ID: 15833865
[TBL] [Abstract][Full Text] [Related]
6. Targeting of O6-MeG DNA methyltransferase (MGMT) to mitochondria protects against alkylation induced cell death.
Rasmussen AK; Rasmussen LJ
Mitochondrion; 2005 Dec; 5(6):411-7. PubMed ID: 16233991
[TBL] [Abstract][Full Text] [Related]
7. p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa.
Valente LJ; Gray DH; Michalak EM; Pinon-Hofbauer J; Egle A; Scott CL; Janic A; Strasser A
Cell Rep; 2013 May; 3(5):1339-45. PubMed ID: 23665218
[TBL] [Abstract][Full Text] [Related]
8. Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents.
Srivenugopal KS; Shou J; Mullapudi SR; Lang FF; Rao JS; Ali-Osman F
Clin Cancer Res; 2001 May; 7(5):1398-409. PubMed ID: 11350911
[TBL] [Abstract][Full Text] [Related]
9. Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine.
Roos WP; Batista LF; Naumann SC; Wick W; Weller M; Menck CF; Kaina B
Oncogene; 2007 Jan; 26(2):186-97. PubMed ID: 16819506
[TBL] [Abstract][Full Text] [Related]
10. Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.
Roos W; Baumgartner M; Kaina B
Oncogene; 2004 Jan; 23(2):359-67. PubMed ID: 14724564
[TBL] [Abstract][Full Text] [Related]
11. Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication.
Aghi M; Rabkin S; Martuza RL
J Natl Cancer Inst; 2006 Jan; 98(1):38-50. PubMed ID: 16391370
[TBL] [Abstract][Full Text] [Related]
12. Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis.
Takagi Y; Takahashi M; Sanada M; Ito R; Yamaizumi M; Sekiguchi M
DNA Repair (Amst); 2003 Oct; 2(10):1135-46. PubMed ID: 13679151
[TBL] [Abstract][Full Text] [Related]
13. p53 Binding to the p21 promoter is dependent on the nature of DNA damage.
Hill R; Bodzak E; Blough MD; Lee PW
Cell Cycle; 2008 Aug; 7(16):2535-43. PubMed ID: 18719376
[TBL] [Abstract][Full Text] [Related]
14. Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells.
Ragg S; Xu-Welliver M; Bailey J; D'Souza M; Cooper R; Chandra S; Seshadri R; Pegg AE; Williams DA
Cancer Res; 2000 Sep; 60(18):5187-95. PubMed ID: 11016647
[TBL] [Abstract][Full Text] [Related]
15. Expression of the human MGMT O6-methylguanine DNA methyltransferase gene in a yeast alkylation-sensitive mutant: its effects on both exogenous and endogenous DNA alkylation damage.
Xiao W; Fontanie T
Mutat Res; 1995 Mar; 336(2):133-42. PubMed ID: 7885384
[TBL] [Abstract][Full Text] [Related]
16. Endoplasmic reticulum protein 29 (ERp29) confers radioresistance through the DNA repair gene, O(6)-methylguanine DNA-methyltransferase, in breast cancer cells.
Chen S; Zhang Y; Zhang D
Sci Rep; 2015 Sep; 5():14723. PubMed ID: 26420420
[TBL] [Abstract][Full Text] [Related]
17. Promoter hypermethylation of the DNA-repair gene O6-methylguanine-DNA methyltransferase and p53 mutation in diffuse large B-cell lymphoma.
Hiraga J; Kinoshita T; Ohno T; Mori N; Ohashi H; Fukami S; Noda A; Ichikawa A; Naoe T
Int J Hematol; 2006 Oct; 84(3):248-55. PubMed ID: 17050200
[TBL] [Abstract][Full Text] [Related]
18. Mouse mutants reveal that putative protein interaction sites in the p53 proline-rich domain are dispensable for tumor suppression.
Toledo F; Lee CJ; Krummel KA; Rodewald LW; Liu CW; Wahl GM
Mol Cell Biol; 2007 Feb; 27(4):1425-32. PubMed ID: 17158931
[TBL] [Abstract][Full Text] [Related]
19. A type I combi-targeting approach for the design of molecules with enhanced potency against BRCA1/2 mutant- and O6-methylguanine-DNA methyltransferase (mgmt)- expressing tumour cells.
Senhaji Mouhri Z; Goodfellow E; Jean-Claude B
BMC Cancer; 2017 Aug; 17(1):540. PubMed ID: 28800752
[TBL] [Abstract][Full Text] [Related]
20. The modified human DNA repair enzyme O(6)-methylguanine-DNA methyltransferase is a negative regulator of estrogen receptor-mediated transcription upon alkylation DNA damage.
Teo AK; Oh HK; Ali RB; Li BF
Mol Cell Biol; 2001 Oct; 21(20):7105-14. PubMed ID: 11564893
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]