936 related articles for article (PubMed ID: 28753941)
1. Proteostasis of Huntingtin in Health and Disease.
Koyuncu S; Fatima A; Gutierrez-Garcia R; Vilchez D
Int J Mol Sci; 2017 Jul; 18(7):. PubMed ID: 28753941
[TBL] [Abstract][Full Text] [Related]
2. Targeting the proteostasis network in Huntington's disease.
Soares TR; Reis SD; Pinho BR; Duchen MR; Oliveira JMA
Ageing Res Rev; 2019 Jan; 49():92-103. PubMed ID: 30502498
[TBL] [Abstract][Full Text] [Related]
3. The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients.
Koyuncu S; Saez I; Lee HJ; Gutierrez-Garcia R; Pokrzywa W; Fatima A; Hoppe T; Vilchez D
Nat Commun; 2018 Jul; 9(1):2886. PubMed ID: 30038412
[TBL] [Abstract][Full Text] [Related]
4. The dynamics of early-state transcriptional changes and aggregate formation in a Huntington's disease cell model.
van Hagen M; Piebes DGE; de Leeuw WC; Vuist IM; van Roon-Mom WMC; Moerland PD; Verschure PJ
BMC Genomics; 2017 May; 18(1):373. PubMed ID: 28499347
[TBL] [Abstract][Full Text] [Related]
5. Exploding the Repeat Length Paradigm while Exploring Amyloid Toxicity in Huntington's Disease.
Wetzel R
Acc Chem Res; 2020 Oct; 53(10):2347-2357. PubMed ID: 32975927
[TBL] [Abstract][Full Text] [Related]
6. Herp Promotes Degradation of Mutant Huntingtin: Involvement of the Proteasome and Molecular Chaperones.
Luo H; Cao L; Liang X; Du A; Peng T; Li H
Mol Neurobiol; 2018 Oct; 55(10):7652-7668. PubMed ID: 29430620
[TBL] [Abstract][Full Text] [Related]
7. Aggregation landscapes of Huntingtin exon 1 protein fragments and the critical repeat length for the onset of Huntington's disease.
Chen M; Wolynes PG
Proc Natl Acad Sci U S A; 2017 Apr; 114(17):4406-4411. PubMed ID: 28400517
[TBL] [Abstract][Full Text] [Related]
8. Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models.
Franich NR; Basso M; André EA; Ochaba J; Kumar A; Thein S; Fote G; Kachemov M; Lau AL; Yeung SY; Osmand A; Zeitlin SO; Ratan RR; Thompson LM; Steffan JS
J Huntingtons Dis; 2018; 7(2):137-150. PubMed ID: 29843246
[TBL] [Abstract][Full Text] [Related]
9. Copper enhances aggregational toxicity of mutant huntingtin in a Drosophila model of Huntington's Disease.
Lobato AG; Ortiz-Vega N; Zhu Y; Neupane D; Meier KK; Zhai RG
Biochim Biophys Acta Mol Basis Dis; 2024 Jan; 1870(1):166928. PubMed ID: 38660915
[TBL] [Abstract][Full Text] [Related]
10. Biophysical Aspect of Huntingtin Protein During polyQ: An In Silico Insight.
Gopalakrishnan C; Jethi S; Kalsi N; Purohit R
Cell Biochem Biophys; 2016 Jun; 74(2):129-39. PubMed ID: 27094178
[TBL] [Abstract][Full Text] [Related]
11. Huntington's Disease.
Finkbeiner S
Cold Spring Harb Perspect Biol; 2011 Jun; 3(6):. PubMed ID: 21441583
[TBL] [Abstract][Full Text] [Related]
12. How Do Post-Translational Modifications Influence the Pathomechanistic Landscape of Huntington's Disease? A Comprehensive Review.
Lontay B; Kiss A; Virág L; Tar K
Int J Mol Sci; 2020 Jun; 21(12):. PubMed ID: 32560122
[TBL] [Abstract][Full Text] [Related]
13. Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex.
Huang B; Guo Q; Niedermeier ML; Cheng J; Engler T; Maurer M; Pautsch A; Baumeister W; Stengel F; Kochanek S; Fernández-Busnadiego R
Structure; 2021 Aug; 29(8):804-809.e5. PubMed ID: 33909994
[TBL] [Abstract][Full Text] [Related]
14. SUMOylation Prevents Huntingtin Fibrillization and Localization onto Lipid Membranes.
Sedighi F; Adegbuyiro A; Legleiter J
ACS Chem Neurosci; 2020 Feb; 11(3):328-343. PubMed ID: 31880908
[TBL] [Abstract][Full Text] [Related]
15. Folding Landscape of Mutant Huntingtin Exon1: Diffusible Multimers, Oligomers and Fibrils, and No Detectable Monomer.
Sahoo B; Arduini I; Drombosky KW; Kodali R; Sanders LH; Greenamyre JT; Wetzel R
PLoS One; 2016; 11(6):e0155747. PubMed ID: 27271685
[TBL] [Abstract][Full Text] [Related]
16. Identification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearance.
Martin DDO; Schmidt ME; Nguyen YT; Lazic N; Hayden MR
FASEB J; 2019 Mar; 33(3):3190-3197. PubMed ID: 30423259
[TBL] [Abstract][Full Text] [Related]
17. PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
Yue HW; Hong JY; Zhang SX; Jiang LL; Hu HY
Sci Rep; 2021 Apr; 11(1):7815. PubMed ID: 33837238
[TBL] [Abstract][Full Text] [Related]
18. Atypical ubiquitination by E3 ligase WWP1 inhibits the proteasome-mediated degradation of mutant huntingtin.
Lin L; Jin Z; Tan H; Xu Q; Peng T; Li H
Brain Res; 2016 Jul; 1643():103-12. PubMed ID: 27107943
[TBL] [Abstract][Full Text] [Related]
19. A PIAS1 Protective Variant S510G Delays polyQ Disease Onset by Modifying Protein Homeostasis.
Lee YH; Tsai YS; Chang CC; Ho CC; Shih HM; Chen HM; Lai HL; Lee CW; Lee YC; Liao YC; Yang UC; Cheng TH; Chern Y; Soong BW
Mov Disord; 2022 Apr; 37(4):767-777. PubMed ID: 34951052
[TBL] [Abstract][Full Text] [Related]
20. G3BP1-dependent mechanism suppressing protein aggregation in Huntington's models and its demise upon stress granule assembly.
Gutiérrez-Garcia R; Koyuncu S; Hommen F; Bilican S; Lee HJ; Fatima A; Vilchez D
Hum Mol Genet; 2023 May; 32(10):1607-1621. PubMed ID: 36611004
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
