158 related articles for article (PubMed ID: 28754437)
1. Inactivation of the orphan nuclear receptor NR4A1 contributes to apoptosis induction by fangchinoline in pancreatic cancer cells.
Lee HS; Safe S; Lee SO
Toxicol Appl Pharmacol; 2017 Oct; 332():32-39. PubMed ID: 28754437
[TBL] [Abstract][Full Text] [Related]
2. Broussochalcone A Is a Novel Inhibitor of the Orphan Nuclear Receptor NR4A1 and Induces Apoptosis in Pancreatic Cancer Cells.
Lee HS; Kim SH; Kim BM; Safe S; Lee SO
Molecules; 2021 Apr; 26(8):. PubMed ID: 33923503
[TBL] [Abstract][Full Text] [Related]
3. The orphan nuclear receptor NR4A1 (Nur77) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells.
Lee SO; Jin UH; Kang JH; Kim SB; Guthrie AS; Sreevalsan S; Lee JS; Safe S
Mol Cancer Res; 2014 Apr; 12(4):527-538. PubMed ID: 24515801
[TBL] [Abstract][Full Text] [Related]
4. The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis.
Yu C; Cui S; Zong C; Gao W; Xu T; Gao P; Chen J; Qin D; Guan Q; Liu Y; Fu Y; Li X; Wang X
J Biol Chem; 2015 Aug; 290(34):20687-20699. PubMed ID: 26157144
[TBL] [Abstract][Full Text] [Related]
5. Plant Alkaloid Tetrandrine Is a Nuclear Receptor 4A1 Antagonist and Inhibits Panc-1 Cell Growth In Vitro and In Vivo.
Lee HS; Kim DH; Lee IS; Park JH; Martin G; Safe S; Kim KJ; Kim JH; Jang BI; Lee SO
Int J Mol Sci; 2022 May; 23(9):. PubMed ID: 35563670
[TBL] [Abstract][Full Text] [Related]
6. Nuclear receptor 4A1 as a drug target for breast cancer chemotherapy.
Hedrick E; Lee SO; Doddapaneni R; Singh M; Safe S
Endocr Relat Cancer; 2015 Oct; 22(5):831-40. PubMed ID: 26229035
[TBL] [Abstract][Full Text] [Related]
7. Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.
Lee SO; Abdelrahim M; Yoon K; Chintharlapalli S; Papineni S; Kim K; Wang H; Safe S
Cancer Res; 2010 Sep; 70(17):6824-36. PubMed ID: 20660371
[TBL] [Abstract][Full Text] [Related]
8. The stress-response molecule NR4A1 resists ROS-induced pancreatic β-cells apoptosis via WT1.
Zong C; Qin D; Yu C; Gao P; Chen J; Lu S; Zhang Y; Liu Y; Yang Y; Pu Z; Li X; Fu Y; Guan Q; Wang X
Cell Signal; 2017 Jul; 35():129-139. PubMed ID: 28342843
[TBL] [Abstract][Full Text] [Related]
9. Fangchinoline inhibits breast adenocarcinoma proliferation by inducing apoptosis.
Xing ZB; Yao L; Zhang GQ; Zhang XY; Zhang YX; Pang D
Chem Pharm Bull (Tokyo); 2011; 59(12):1476-80. PubMed ID: 22130369
[TBL] [Abstract][Full Text] [Related]
10. The orphan nuclear receptor NR4A1 attenuates oxidative stress-induced β cells apoptosis via up-regulation of glutathione peroxidase 1.
Yang Y; Xie F; Qin D; Zong C; Han F; Pu Z; Liu D; Li X; Zhang Y; Liu Y; Wang X
Life Sci; 2018 Jun; 203():225-232. PubMed ID: 29678743
[TBL] [Abstract][Full Text] [Related]
11. Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors.
Yoon K; Lee SO; Cho SD; Kim K; Khan S; Safe S
Carcinogenesis; 2011 Jun; 32(6):836-42. PubMed ID: 21362629
[TBL] [Abstract][Full Text] [Related]
12. Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania tetrandra can reverse multidrug resistance by inhibiting P-glycoprotein activity in multidrug resistant human cancer cells.
Sun YF; Wink M
Phytomedicine; 2014; 21(8-9):1110-9. PubMed ID: 24856768
[TBL] [Abstract][Full Text] [Related]
13. New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy.
Zhang L; Liu W; Wang Q; Li Q; Wang H; Wang J; Teng T; Chen M; Ji A; Li Y
Molecules; 2018 Mar; 23(3):. PubMed ID: 29498706
[TBL] [Abstract][Full Text] [Related]
14. Fangchinoline Induces Apoptosis, Autophagy and Energetic Impairment in Bladder Cancer.
Fan B; Zhang X; Ma Y; Zhang A
Cell Physiol Biochem; 2017; 43(3):1003-1011. PubMed ID: 28968601
[TBL] [Abstract][Full Text] [Related]
15. Molecular Targets Modulated by Fangchinoline in Tumor Cells and Preclinical Models.
Mérarchi M; Sethi G; Fan L; Mishra S; Arfuso F; Ahn KS
Molecules; 2018 Oct; 23(10):. PubMed ID: 30301146
[TBL] [Abstract][Full Text] [Related]
16. NR4A1 counteracts JNK activation incurred by ER stress or ROS in pancreatic β-cells for protection.
Pu ZQ; Liu D; Lobo Mouguegue HPP; Jin CW; Sadiq E; Qin DD; Yu TF; Zong C; Chen JC; Zhao RX; Lin JY; Cheng J; Yu X; Li X; Zhang YC; Liu YT; Guan QB; Wang XD
J Cell Mol Med; 2020 Dec; 24(24):14171-14183. PubMed ID: 33124187
[TBL] [Abstract][Full Text] [Related]
17. Targeting NR4A1 (TR3) in cancer cells and tumors.
Lee SO; Li X; Khan S; Safe S
Expert Opin Ther Targets; 2011 Feb; 15(2):195-206. PubMed ID: 21204731
[TBL] [Abstract][Full Text] [Related]
18. Non-genomic effects of the NR4A1/Nur77/TR3/NGFIB orphan nuclear receptor.
Pawlak A; Strzadala L; Kalas W
Steroids; 2015 Mar; 95():1-6. PubMed ID: 25555471
[TBL] [Abstract][Full Text] [Related]
19. The nuclear orphan receptor NR4A1 regulates β1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonists.
Hedrick E; Lee SO; Safe S
Mol Carcinog; 2017 Sep; 56(9):2066-2075. PubMed ID: 28418095
[TBL] [Abstract][Full Text] [Related]
20. The nuclear orphan receptors NR4A as therapeutic target in cancer therapy.
Deutsch AJ; Angerer H; Fuchs TE; Neumeister P
Anticancer Agents Med Chem; 2012 Nov; 12(9):1001-14. PubMed ID: 22583411
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
