264 related articles for article (PubMed ID: 28755970)
1. Differences of first-pass effect in the liver and intestine contribute to the stereoselective pharmacokinetics of rhynchophylline and isorhynchophylline epimers in rats.
Wang X; Zheng M; Liu J; Huang Z; Bai Y; Ren Z; Wang Z; Tian Y; Qiao Z; Liu W; Feng F
J Ethnopharmacol; 2017 Sep; 209():175-183. PubMed ID: 28755970
[TBL] [Abstract][Full Text] [Related]
2. Stereoselective in vitro metabolism of rhynchophylline and isorhynchophylline epimers of Uncaria rhynchophylla in rat liver microsomes.
Wang X; Qiao Z; Liu J; Zheng M; Liu W; Wu C
Xenobiotica; 2018 Oct; 48(10):990-998. PubMed ID: 28990840
[TBL] [Abstract][Full Text] [Related]
3. Stereoselective pharmacokinetic study of rhynchophylline and isorhynchophylline epimers in rat plasma by liquid chromatography-tandem mass spectrometry.
Wang X; Zheng M; Liu J; Qiao Z; Liu W; Feng F
Xenobiotica; 2017 Jun; 47(6):479-487. PubMed ID: 27388920
[TBL] [Abstract][Full Text] [Related]
4. Biotransformation and pharmacokinetic studies of four alkaloids from Uncaria rhynchophylla in rat plasma by ultra-performance liquid chromatography with tandem mass spectrometry.
Jiang S; Yang X; Wang Z; Gan C; Huang J; Sun J; Peng H; Wei F; Wang Z; Yang C
J Pharm Biomed Anal; 2022 Sep; 218():114858. PubMed ID: 35691093
[TBL] [Abstract][Full Text] [Related]
5. Transcriptome revealing the dual regulatory mechanism of ethylene on the rhynchophylline and isorhynchophylline in Uncaria rhynchophylla.
Li X; Wang XH; Qiang W; Zheng HJ; ShangGuan LY; Zhang MS
J Plant Res; 2022 May; 135(3):485-500. PubMed ID: 35380307
[TBL] [Abstract][Full Text] [Related]
6. Anti-inflammatory effects of rhynchophylline and isorhynchophylline in mouse N9 microglial cells and the molecular mechanism.
Yuan D; Ma B; Yang JY; Xie YY; Wang L; Zhang LJ; Kano Y; Wu CF
Int Immunopharmacol; 2009 Dec; 9(13-14):1549-54. PubMed ID: 19781666
[TBL] [Abstract][Full Text] [Related]
7. De novo transcriptome sequencing and digital gene expression analysis predict biosynthetic pathway of rhynchophylline and isorhynchophylline from Uncaria rhynchophylla, a non-model plant with potent anti-alzheimer's properties.
Guo Q; Ma X; Wei S; Qiu D; Wilson IW; Wu P; Tang Q; Liu L; Dong S; Zu W
BMC Genomics; 2014 Aug; 15(1):676. PubMed ID: 25112168
[TBL] [Abstract][Full Text] [Related]
8. Pharmacokinetic study of isocorynoxeine metabolites mediated by cytochrome P450 enzymes in rat and human liver microsomes.
Zhao L; Zang B; Qi W; Chen F; Wang H; Kano Y; Yuan D
Fitoterapia; 2016 Jun; 111():49-57. PubMed ID: 27094112
[TBL] [Abstract][Full Text] [Related]
9. The effects of genetic variation and environmental factors on rhynchophylline and isorhynchophylline in Uncaria macrophylla Wall. from different populations in China.
Song MF; Guan YH; Li HT; Wei SG; Zhang LX; Zhang ZL; Ma XJ
PLoS One; 2018; 13(6):e0199259. PubMed ID: 29953548
[TBL] [Abstract][Full Text] [Related]
10. Evidence on Integrating Pharmacokinetics to Find Truly Therapeutic Agent for Alzheimer's Disease: Comparative Pharmacokinetics and Disposition Kinetics Profiles of Stereoisomers Isorhynchophylline and Rhynchophylline in Rats.
Zhang C; Wu X; Xian Y; Zhu L; Lin G; Lin ZX
Evid Based Complement Alternat Med; 2019; 2019():4016323. PubMed ID: 30854007
[TBL] [Abstract][Full Text] [Related]
11. Stereoselective first-pass metabolism of verapamil in the small intestine and liver in rats.
Hanada K; Ikemi Y; Kukita K; Mihara K; Ogata H
Drug Metab Dispos; 2008 Oct; 36(10):2037-42. PubMed ID: 18617604
[TBL] [Abstract][Full Text] [Related]
12. Profiles of Metabolic Genes in
Yang M; Yao B; Lin R
Biomolecules; 2022 Nov; 12(12):. PubMed ID: 36551218
[TBL] [Abstract][Full Text] [Related]
13. Pharmacokinetics of DA-8159, a new erectogenic, after intravenous and oral administration to rats: hepatic and intestinal first-pass effects.
Shim HJ; Kim YC; Park KJ; Kim DS; Kwon JW; Kim WB; Lee MG
J Pharm Sci; 2003 Nov; 92(11):2185-95. PubMed ID: 14603504
[TBL] [Abstract][Full Text] [Related]
14. Preclinical pharmacokinetics and in vitro metabolism of dasatinib (BMS-354825): a potent oral multi-targeted kinase inhibitor against SRC and BCR-ABL.
Kamath AV; Wang J; Lee FY; Marathe PH
Cancer Chemother Pharmacol; 2008 Mar; 61(3):365-76. PubMed ID: 17429625
[TBL] [Abstract][Full Text] [Related]
15. Stereoselective property of 20(S)-protopanaxadiol ocotillol type epimers affects its absorption and also the inhibition of P-glycoprotein.
Wang W; Wu X; Wang L; Meng Q; Liu W
PLoS One; 2014; 9(6):e98887. PubMed ID: 24887182
[TBL] [Abstract][Full Text] [Related]
16. Comparative pharmacokinetics of arctigenin in normal and type 2 diabetic rats after oral and intravenous administration.
Zeng XY; Dong S; He NN; Jiang CJ; Dai Y; Xia YF
Fitoterapia; 2015 Sep; 105():119-26. PubMed ID: 26102179
[TBL] [Abstract][Full Text] [Related]
17. The Disposition of Oxymatrine in the Vascularly Perfused Rat Intestine-Liver Preparation and Its Metabolism in Rat Liver Microsomes.
Huang LH; Zhong YM; Xiong XH; Cen MF; Cheng XG; Wang GX; Chen JS; Wang SJ
J Pharm Sci; 2016 Feb; 105(2):897-903. PubMed ID: 26869434
[TBL] [Abstract][Full Text] [Related]
18. Hepatic and gastrointestinal first-pass effects of vitexin-4″-O-glucoside in rats.
Chen Y; Zhang W; Li D; Ai J; Meng Y; Ying X; Kang T
J Pharm Pharmacol; 2013 Oct; 65(10):1500-7. PubMed ID: 24028617
[TBL] [Abstract][Full Text] [Related]
19. Comparative transcriptome analysis revealed the molecular mechanism of the effect of light intensity on the accumulation of rhynchophylline and isorhynchophylline in
Wang XH; Li X; Qiang W; Yu XS; Zheng HJ; Zhang MS
Physiol Mol Biol Plants; 2022 Feb; 28(2):315-331. PubMed ID: 35400883
[TBL] [Abstract][Full Text] [Related]
20. Assessment of intestinal availability of various drugs in the oral absorption process using portal vein-cannulated rats.
Matsuda Y; Konno Y; Satsukawa M; Kobayashi T; Takimoto Y; Morisaki K; Yamashita S
Drug Metab Dispos; 2012 Dec; 40(12):2231-8. PubMed ID: 22930277
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
