BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

39 related articles for article (PubMed ID: 28767177)

  • 1. Intrinsically disordered regions regulate both catalytic and non-catalytic activities of the MutLα mismatch repair complex.
    Kim Y; Furman CM; Manhart CM; Alani E; Finkelstein IJ
    Nucleic Acids Res; 2019 Feb; 47(4):1823-1835. PubMed ID: 30541127
    [TBL] [Abstract][Full Text] [Related]  

  • 2. All three mammalian MutL complexes are required for repeat expansion in a mouse cell model of the Fragile X-related disorders.
    Miller CJ; Kim GY; Zhao X; Usdin K
    PLoS Genet; 2020 Jun; 16(6):e1008902. PubMed ID: 32589669
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Punctate MLH1 mismatch repair immunostaining in colorectal cancer.
    Loughrey MB; Dunne PD; Coleman HG; McQuaid S; James JA
    Histopathology; 2019 Apr; 74(5):795-797. PubMed ID: 30379344
    [No Abstract]   [Full Text] [Related]  

  • 4. MutLα suppresses error-prone DNA mismatch repair and preferentially protects noncoding DNA from mutations.
    Kadyrova LY; Mieczkowski PA; Kadyrov FA
    J Biol Chem; 2024 May; 300(6):107406. PubMed ID: 38782208
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mismatch repair protein MLH1 suppresses replicative stress in BRCA2-deficient breast tumors.
    Sengodan SK; Hu X; Peddibhotla V; Balamurugan K; Mitrophanov AY; McKennett L; Kharat SS; Sanawar R; Singh VK; Albaugh ME; Burkett SS; Zhao Y; Tran B; Malys T; Sterneck E; De S; Sharan SK
    J Clin Invest; 2024 Jan; 134(7):. PubMed ID: 38271119
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of a Catalytic Lysine Residue Conserved Among GHKL ATPases: MutL, GyrB, and MORC.
    Fukui K; Fujii Y; Yano T
    J Mol Biol; 2024 May; 436(10):168575. PubMed ID: 38641238
    [TBL] [Abstract][Full Text] [Related]  

  • 7. All three MutL complexes are required for repeat expansion in a human stem cell model of CAG-repeat expansion mediated glutaminase deficiency.
    Hayward B; Kumari D; Santra S; van Karnebeek CDM; van Kuilenburg ABP; Usdin K
    Sci Rep; 2024 Jun; 14(1):13772. PubMed ID: 38877099
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MutLα suppresses error-prone DNA mismatch repair and preferentially protects noncoding DNA from mutations.
    Kadyrova LY; Mieczkowski PA; Kadyrov FA
    bioRxiv; 2024 Apr; ():. PubMed ID: 38617288
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification PMS1 and PMS2 as potential meiotic substrates of CDK2 activity.
    Palmer N; Talib SZA; Goh CMF; Biswas K; Sharan SK; Kaldis P
    PLoS One; 2023; 18(3):e0283590. PubMed ID: 36952545
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lynch syndrome, molecular mechanisms and variant classification.
    Abildgaard AB; Nielsen SV; Bernstein I; Stein A; Lindorff-Larsen K; Hartmann-Petersen R
    Br J Cancer; 2023 Mar; 128(5):726-734. PubMed ID: 36434153
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of ABL1 by tyrosine kinase inhibitors leads to a downregulation of MLH1 by Hsp70-mediated lysosomal protein degradation.
    Daniels HG; Knicely BG; Miller AK; Thompson A; Plattner R; Goellner EM
    Front Genet; 2022; 13():940073. PubMed ID: 36338985
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PMS2 variant results in loss of ATPase activity without compromising mismatch repair.
    D'Arcy BM; Arrington J; Weisman J; McClellan SB; Vandana ; Yang Z; Deivanayagam C; Blount J; Prakash A
    Mol Genet Genomic Med; 2022 Feb; 10(5):e1908. PubMed ID: 35189042
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Narrative review of emerging roles for AKT-mTOR signaling in cancer radioimmunotherapy.
    Shen C; He Y; Chen Q; Feng H; Williams TM; Lu Y; He Z
    Ann Transl Med; 2021 Oct; 9(20):1596. PubMed ID: 34790802
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Novel Germline
    Klančar G; Blatnik A; Šetrajčič Dragoš V; Vogrič V; Stegel V; Blatnik O; Drev P; Gazič B; Krajc M; Novaković S
    Genes (Basel); 2020 Mar; 11(3):. PubMed ID: 32197529
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome.
    Abildgaard AB; Stein A; Nielsen SV; Schultz-Knudsen K; Papaleo E; Shrikhande A; Hoffmann ER; Bernstein I; Gerdes AM; Takahashi M; Ishioka C; Lindorff-Larsen K; Hartmann-Petersen R
    Elife; 2019 Nov; 8():. PubMed ID: 31697235
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biochemical and structural characterization of two variants of uncertain significance in the PMS2 gene.
    D'Arcy BM; Blount J; Prakash A
    Hum Mutat; 2019 Apr; 40(4):458-471. PubMed ID: 30653781
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphorylation-dependent signaling controls degradation of DNA mismatch repair protein PMS2.
    Hinrichsen I; Weßbecher IM; Huhn M; Passmann S; Zeuzem S; Plotz G; Biondi RM; Brieger A
    Mol Carcinog; 2017 Dec; 56(12):2663-2668. PubMed ID: 28767177
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA mismatch repair activity of MutLα is regulated by CK2-dependent phosphorylation of MLH1 (S477).
    Weßbecher IM; Hinrichsen I; Funke S; Oellerich T; Plotz G; Zeuzem S; Grus FH; Biondi RM; Brieger A
    Mol Carcinog; 2018 Dec; 57(12):1723-1734. PubMed ID: 30136313
    [TBL] [Abstract][Full Text] [Related]  

  • 19.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 2.