BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 28768682)

  • 1. Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity.
    Achour B; Dantonio A; Niosi M; Novak JJ; Fallon JK; Barber J; Smith PC; Rostami-Hodjegan A; Goosen TC
    Drug Metab Dispos; 2017 Oct; 45(10):1102-1112. PubMed ID: 28768682
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5'-Diphosphate-Glucuronosyltransferase Enzymes with Reference to Catalytic Activity.
    Achour B; Dantonio A; Niosi M; Novak JJ; Al-Majdoub ZM; Goosen TC; Rostami-Hodjegan A; Barber J
    Drug Metab Dispos; 2018 Jun; 46(6):805-812. PubMed ID: 29581103
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes.
    Takahashi RH; Forrest WF; Smith AD; Badee J; Qiu N; Schmidt S; Collier AC; Parrott N; Fowler S
    Drug Metab Dispos; 2021 Sep; 49(9):760-769. PubMed ID: 34187837
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kinetics of acetaminophen glucuronidation by UDP-glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential implications in acetaminophen-induced hepatotoxicity.
    Mutlib AE; Goosen TC; Bauman JN; Williams JA; Kulkarni S; Kostrubsky S
    Chem Res Toxicol; 2006 May; 19(5):701-9. PubMed ID: 16696573
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein expression of various hepatic uridine 5'-diphosphate glucuronosyltransferase (UGT) enzymes and their inter-correlations: a meta-analysis.
    Achour B; Rostami-Hodjegan A; Barber J
    Biopharm Drug Dispos; 2014 Sep; 35(6):353-61. PubMed ID: 24931139
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantification of Accurate Composition and Total Abundance of Homologous Proteins by Conserved-Plus-Surrogate Peptide Approach: Quantification of UDP Glucuronosyltransferases in Human Tissues.
    Ahire D; Patel M; Deshmukh SV; Prasad B
    Drug Metab Dispos; 2023 Mar; 51(3):285-292. PubMed ID: 36446609
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of the Ontogeny of Hepatic UDP-Glucuronosyltransferase Enzymes Based on Glucuronidation Activity Measured in Human Liver Microsomes.
    Badée J; Qiu N; Collier AC; Takahashi RH; Forrest WF; Parrott N; Schmidt S; Fowler S
    J Clin Pharmacol; 2019 Sep; 59 Suppl 1():S42-S55. PubMed ID: 31502688
    [TBL] [Abstract][Full Text] [Related]  

  • 8. S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen.
    Bowalgaha K; Elliot DJ; Mackenzie PI; Knights KM; Swedmark S; Miners JO
    Br J Clin Pharmacol; 2005 Oct; 60(4):423-33. PubMed ID: 16187975
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes.
    Kuehl GE; Lampe JW; Potter JD; Bigler J
    Drug Metab Dispos; 2005 Jul; 33(7):1027-35. PubMed ID: 15843492
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Direct comparison of UDP-glucuronosyltransferase and cytochrome P450 activities in human liver microsomes, plated and suspended primary human hepatocytes from five liver donors.
    den Braver-Sewradj SP; den Braver MW; Baze A; Decorde J; Fonsi M; Bachellier P; Vermeulen NPE; Commandeur JNM; Richert L; Vos JC
    Eur J Pharm Sci; 2017 Nov; 109():96-110. PubMed ID: 28778465
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glucuronidation of the aspirin metabolite salicylic acid by expressed UDP-glucuronosyltransferases and human liver microsomes.
    Kuehl GE; Bigler J; Potter JD; Lampe JW
    Drug Metab Dispos; 2006 Feb; 34(2):199-202. PubMed ID: 16258079
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glucuronidation of capsaicin by liver microsomes and expressed UGT enzymes: reaction kinetics, contribution of individual enzymes and marked species differences.
    Sun H; Wang H; Liu H; Zhang X; Wu B
    Expert Opin Drug Metab Toxicol; 2014 Oct; 10(10):1325-36. PubMed ID: 25219630
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Simultaneous quantification of the abundance of several cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase enzymes in human liver microsomes using multiplexed targeted proteomics.
    Achour B; Russell MR; Barber J; Rostami-Hodjegan A
    Drug Metab Dispos; 2014 Apr; 42(4):500-10. PubMed ID: 24408517
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system.
    Court MH
    Drug Metab Rev; 2010 Feb; 42(1):209-24. PubMed ID: 19821798
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver.
    Mano Y; Usui T; Kamimura H
    Drug Metab Dispos; 2007 Jul; 35(7):1182-7. PubMed ID: 17446261
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An investigation of human and rat liver microsomal mycophenolic acid glucuronidation: evidence for a principal role of UGT1A enzymes and species differences in UGT1A specificity.
    Miles KK; Stern ST; Smith PC; Kessler FK; Ali S; Ritter JK
    Drug Metab Dispos; 2005 Oct; 33(10):1513-20. PubMed ID: 16033946
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms.
    Court MH; Duan SX; von Moltke LL; Greenblatt DJ; Patten CJ; Miners JO; Mackenzie PI
    J Pharmacol Exp Ther; 2001 Dec; 299(3):998-1006. PubMed ID: 11714888
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Optimized methods for targeted peptide-based quantification of human uridine 5'-diphosphate-glucuronosyltransferases in biological specimens using liquid chromatography-tandem mass spectrometry.
    Sato Y; Nagata M; Tetsuka K; Tamura K; Miyashita A; Kawamura A; Usui T
    Drug Metab Dispos; 2014 May; 42(5):885-9. PubMed ID: 24595681
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of human UDP-glucuronosyltransferase isoform(s) responsible for the C-glucuronidation of phenylbutazone.
    Nishiyama T; Kobori T; Arai K; Ogura K; Ohnuma T; Ishii K; Hayashi K; Hiratsuka A
    Arch Biochem Biophys; 2006 Oct; 454(1):72-9. PubMed ID: 16949544
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of UDP-glucuronosyltransferases involved in the metabolism of silymarin flavonolignans.
    Vrba J; Papoušková B; Lněničková K; Kosina P; Křen V; Ulrichová J
    J Pharm Biomed Anal; 2020 Jan; 178():112972. PubMed ID: 31727359
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.