These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 28768899)

  • 1. Aberrant perichondrial BMP signaling mediates multiple osteochondromagenesis in mice.
    Inubushi T; Nozawa S; Matsumoto K; Irie F; Yamaguchi Y
    JCI Insight; 2017 Aug; 2(15):. PubMed ID: 28768899
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Palovarotene Inhibits Osteochondroma Formation in a Mouse Model of Multiple Hereditary Exostoses.
    Inubushi T; Lemire I; Irie F; Yamaguchi Y
    J Bone Miner Res; 2018 Apr; 33(4):658-666. PubMed ID: 29120519
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The pathogenic roles of heparan sulfate deficiency in hereditary multiple exostoses.
    Pacifici M
    Matrix Biol; 2018 Oct; 71-72():28-39. PubMed ID: 29277722
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A mouse model of chondrocyte-specific somatic mutation reveals a role for Ext1 loss of heterozygosity in multiple hereditary exostoses.
    Matsumoto K; Irie F; Mackem S; Yamaguchi Y
    Proc Natl Acad Sci U S A; 2010 Jun; 107(24):10932-7. PubMed ID: 20534475
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice.
    Sinha S; Mundy C; Bechtold T; Sgariglia F; Ibrahim MM; Billings PC; Carroll K; Koyama E; Jones KB; Pacifici M
    PLoS Genet; 2017 Apr; 13(4):e1006742. PubMed ID: 28445472
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses.
    Huegel J; Mundy C; Sgariglia F; Nygren P; Billings PC; Yamaguchi Y; Koyama E; Pacifici M
    Dev Biol; 2013 May; 377(1):100-12. PubMed ID: 23458899
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones.
    Zak BM; Schuksz M; Koyama E; Mundy C; Wells DE; Yamaguchi Y; Pacifici M; Esko JD
    Bone; 2011 May; 48(5):979-87. PubMed ID: 21310272
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Signaling systems affecting the severity of multiple osteochondromas.
    Piombo V; Jochmann K; Hoffmann D; Wuelling M; Vortkamp A
    Bone; 2018 Jun; 111():71-81. PubMed ID: 29545125
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heparan sulfate antagonism alters bone morphogenetic protein signaling and receptor dynamics, suggesting a mechanism in hereditary multiple exostoses.
    Mundy C; Yang E; Takano H; Billings PC; Pacifici M
    J Biol Chem; 2018 May; 293(20):7703-7716. PubMed ID: 29622677
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cell biology of osteochondromas: bone morphogenic protein signalling and heparan sulphates.
    Cuellar A; Reddi AH
    Int Orthop; 2013 Aug; 37(8):1591-6. PubMed ID: 23771188
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differentiation-induced loss of heparan sulfate in human exostosis derived chondrocytes.
    Hecht JT; Hayes E; Haynes R; Cole WG; Long RJ; Farach-Carson MC; Carson DD
    Differentiation; 2005 Jun; 73(5):212-21. PubMed ID: 16026543
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Multiple hereditary exostoses (MHE): elucidating the pathogenesis of a rare skeletal disorder through interdisciplinary research.
    Jones KB; Pacifici M; Hilton MJ
    Connect Tissue Res; 2014 Apr; 55(2):80-8. PubMed ID: 24409815
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Advances in the pathogenesis and possible treatments for multiple hereditary exostoses from the 2016 international MHE conference.
    Phan AQ; Pacifici M; Esko JD
    Connect Tissue Res; 2018 Jan; 59(1):85-98. PubMed ID: 29099240
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transgenic expression of the EXT2 gene in developing chondrocytes enhances the synthesis of heparan sulfate and bone formation in mice.
    Morimoto K; Shimizu T; Furukawa K; Morio H; Kurosawa H; Shirasawa T
    Biochem Biophys Res Commun; 2002 Apr; 292(4):999-1009. PubMed ID: 11944914
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The short-lived exostosis induced surgically versus the lasting genetic hereditary multiple exostoses.
    Trebicz-Geffen M; Nevo Z; Evron Z; Posternak N; Glaser T; Fridkin M; Kollander Y; Robinson D
    Exp Mol Pathol; 2003 Feb; 74(1):40-8. PubMed ID: 12645631
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An optimized DHPLC protocol for molecular testing of the EXT1 and EXT2 genes in hereditary multiple osteochondromas.
    Wuyts W; Radersma R; Storm K; Vits L
    Clin Genet; 2005 Dec; 68(6):542-7. PubMed ID: 16283885
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Secondary peripheral chondrosarcoma evolving from osteochondroma as a result of outgrowth of cells with functional EXT.
    de Andrea CE; Reijnders CM; Kroon HM; de Jong D; Hogendoorn PC; Szuhai K; Bovée JV
    Oncogene; 2012 Mar; 31(9):1095-104. PubMed ID: 21804604
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Toward an understanding of the short bone phenotype associated with multiple osteochondromas.
    Jones KB; Datar M; Ravichandran S; Jin H; Jurrus E; Whitaker R; Capecchi MR
    J Orthop Res; 2013 Apr; 31(4):651-7. PubMed ID: 23192691
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biosynthesis of heparan sulfate in EXT1-deficient cells.
    Okada M; Nadanaka S; Shoji N; Tamura J; Kitagawa H
    Biochem J; 2010 May; 428(3):463-71. PubMed ID: 20377530
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Conditional ablation of the heparan sulfate-synthesizing enzyme Ext1 leads to dysregulation of bone morphogenic protein signaling and severe skeletal defects.
    Matsumoto Y; Matsumoto K; Irie F; Fukushi J; Stallcup WB; Yamaguchi Y
    J Biol Chem; 2010 Jun; 285(25):19227-34. PubMed ID: 20404326
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.