237 related articles for article (PubMed ID: 28771808)
1. cAMP/PKA signaling pathway contributes to neuronal apoptosis via regulating IDE expression in a mixed model of type 2 diabetes and Alzheimer's disease.
Li H; Yang S; Wu J; Ji L; Zhu L; Cao L; Huang J; Jiang Q; Wei J; Liu M; Mao K; Wei N; Xie W; Yang Z
J Cell Biochem; 2018 Feb; 119(2):1616-1626. PubMed ID: 28771808
[TBL] [Abstract][Full Text] [Related]
2. Insulin degrading enzyme contributes to the pathology in a mixed model of Type 2 diabetes and Alzheimer's disease: possible mechanisms of IDE in T2D and AD.
Li H; Wu J; Zhu L; Sha L; Yang S; Wei J; Ji L; Tang X; Mao K; Cao L; Wei N; Xie W; Yang Z
Biosci Rep; 2018 Feb; 38(1):. PubMed ID: 29222348
[TBL] [Abstract][Full Text] [Related]
3. GLP-1 receptor regulates cell growth through regulating IDE expression level in Aβ1-42-treated PC12 cells.
Li H; Cao L; Ren Y; Jiang Y; Xie W; Li D
Biosci Rep; 2018 Aug; 38(4):. PubMed ID: 29263141
[TBL] [Abstract][Full Text] [Related]
4. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.
Farris W; Mansourian S; Chang Y; Lindsley L; Eckman EA; Frosch MP; Eckman CB; Tanzi RE; Selkoe DJ; Guenette S
Proc Natl Acad Sci U S A; 2003 Apr; 100(7):4162-7. PubMed ID: 12634421
[TBL] [Abstract][Full Text] [Related]
5. Interactive involvement of hippocampal cAMP/PKA and cyclooxygenase-2 signaling pathways in spatial learning in the Morris water maze.
Tabrizian K; Hashemzaei M; Nasiri AA; Najafi S; Amelinia F; Sanati M; Shamshirgaran F; Fanoudi S
Folia Neuropathol; 2018; 56(1):58-66. PubMed ID: 29663741
[TBL] [Abstract][Full Text] [Related]
6. GLP-1 improves the neuronal supportive ability of astrocytes in Alzheimer's disease by regulating mitochondrial dysfunction via the cAMP/PKA pathway.
Xie Y; Zheng J; Li S; Li H; Zhou Y; Zheng W; Zhang M; Liu L; Chen Z
Biochem Pharmacol; 2021 Jun; 188():114578. PubMed ID: 33895160
[TBL] [Abstract][Full Text] [Related]
7. Interplay between Alzheimer's disease and global glucose metabolism revealed by the metabolic profile alterations of pancreatic tissue and serum in APP/PS1 transgenic mice.
Liu X; Wang W; Chen HL; Zhang HY; Zhang NX
Acta Pharmacol Sin; 2019 Oct; 40(10):1259-1268. PubMed ID: 31089202
[TBL] [Abstract][Full Text] [Related]
8. Up-regulation of IL-4 production by the activated cAMP/cAMP-dependent protein kinase (protein kinase A) pathway in CD3/CD28-stimulated naive T cells.
Tokoyoda K; Tsujikawa K; Matsushita H; Ono Y; Hayashi T; Harada Y; Abe R; Kubo M; Yamamoto H
Int Immunol; 2004 May; 16(5):643-53. PubMed ID: 15096485
[TBL] [Abstract][Full Text] [Related]
9. Adiponectin suppression of high-glucose-induced reactive oxygen species in vascular endothelial cells: evidence for involvement of a cAMP signaling pathway.
Ouedraogo R; Wu X; Xu SQ; Fuchsel L; Motoshima H; Mahadev K; Hough K; Scalia R; Goldstein BJ
Diabetes; 2006 Jun; 55(6):1840-6. PubMed ID: 16731851
[TBL] [Abstract][Full Text] [Related]
10. Overexpressed HspB6 Underlines a Novel Inhibitory Role in Kainic Acid-Induced Epileptic Seizure in Rats by Activating the cAMP-PKA Pathway.
Qi AQ; Zhang YH; Qi QD; Liu YH; Zhu JL
Cell Mol Neurobiol; 2019 Jan; 39(1):111-122. PubMed ID: 30511325
[TBL] [Abstract][Full Text] [Related]
11. 17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention.
Zhao L; Yao J; Mao Z; Chen S; Wang Y; Brinton RD
Neurobiol Aging; 2011 Nov; 32(11):1949-63. PubMed ID: 20053478
[TBL] [Abstract][Full Text] [Related]
12. Cooperative therapeutic action of retinoic acid receptor and retinoid x receptor agonists in a mouse model of Alzheimer's disease.
Kawahara K; Suenobu M; Ohtsuka H; Kuniyasu A; Sugimoto Y; Nakagomi M; Fukasawa H; Shudo K; Nakayama H
J Alzheimers Dis; 2014; 42(2):587-605. PubMed ID: 24916544
[TBL] [Abstract][Full Text] [Related]
13. Central vascular disease and exacerbated pathology in a mixed model of type 2 diabetes and Alzheimer's disease.
Ramos-Rodriguez JJ; Jimenez-Palomares M; Murillo-Carretero MI; Infante-Garcia C; Berrocoso E; Hernandez-Pacho F; Lechuga-Sancho AM; Cozar-Castellano I; Garcia-Alloza M
Psychoneuroendocrinology; 2015 Dec; 62():69-79. PubMed ID: 26254770
[TBL] [Abstract][Full Text] [Related]
14. Targeting cAMP/PKA pathway for glycemic control and type 2 diabetes therapy.
Yang H; Yang L
J Mol Endocrinol; 2016 Aug; 57(2):R93-R108. PubMed ID: 27194812
[TBL] [Abstract][Full Text] [Related]
15. Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis.
Qiu WQ; Folstein MF
Neurobiol Aging; 2006 Feb; 27(2):190-8. PubMed ID: 16399206
[TBL] [Abstract][Full Text] [Related]
16. Impact of Insulin Degrading Enzyme and Neprilysin in Alzheimer's Disease Biology: Characterization of Putative Cognates for Therapeutic Applications.
Jha NK; Jha SK; Kumar D; Kejriwal N; Sharma R; Ambasta RK; Kumar P
J Alzheimers Dis; 2015; 48(4):891-917. PubMed ID: 26444774
[TBL] [Abstract][Full Text] [Related]
17. Antidiabetic Polypill Improves Central Pathology and Cognitive Impairment in a Mixed Model of Alzheimer's Disease and Type 2 Diabetes.
Infante-Garcia C; Ramos-Rodriguez JJ; Hierro-Bujalance C; Ortegon E; Pickett E; Jackson R; Hernandez-Pacho F; Spires-Jones T; Garcia-Alloza M
Mol Neurobiol; 2018 Jul; 55(7):6130-6144. PubMed ID: 29224179
[TBL] [Abstract][Full Text] [Related]
18. Insulin-degrading enzyme antagonizes insulin-dependent tissue growth and Abeta-induced neurotoxicity in Drosophila.
Tsuda M; Kobayashi T; Matsuo T; Aigaki T
FEBS Lett; 2010 Jul; 584(13):2916-20. PubMed ID: 20493190
[TBL] [Abstract][Full Text] [Related]
19. Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention.
Zhao L; Teter B; Morihara T; Lim GP; Ambegaokar SS; Ubeda OJ; Frautschy SA; Cole GM
J Neurosci; 2004 Dec; 24(49):11120-6. PubMed ID: 15590928
[TBL] [Abstract][Full Text] [Related]
20. Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein.
Farris W; Mansourian S; Leissring MA; Eckman EA; Bertram L; Eckman CB; Tanzi RE; Selkoe DJ
Am J Pathol; 2004 Apr; 164(4):1425-34. PubMed ID: 15039230
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]