BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 28780372)

  • 1. Species-specific effects of neuregulin-1β (cimaglermin alfa) on glucose handling in animal models and humans with heart failure.
    Huang Z; Sawyer DB; Troy EL; McEwen C; Cleator JH; Murphy A; Caggiano AO; Eisen A; Parry TJ
    Toxicol Appl Pharmacol; 2017 Oct; 332():92-99. PubMed ID: 28780372
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of neuregulin GGF2 (cimaglermin alfa) dose and treatment frequency on left ventricular function in rats following myocardial infarction.
    Parry TJ; Ganguly A; Troy EL; Luis Guerrero J; Iaci JF; Srinivas M; Vecchione AM; Button DC; Hackett CS; Zolty R; Sawyer DB; Caggiano AO
    Eur J Pharmacol; 2017 Feb; 796():76-89. PubMed ID: 27993643
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An optimized dosing regimen of cimaglermin (neuregulin 1β3, glial growth factor 2) enhances molecular markers of neuroplasticity and functional recovery after permanent ischemic stroke in rats.
    Iaci JF; Parry TJ; Huang Z; Pavlopoulos E; Finklestein SP; Ren J; Caggiano A
    J Neurosci Res; 2016 Mar; 94(3):253-65. PubMed ID: 26660233
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transient Changes in Hepatic Physiology That Alter Bilirubin and Bile Acid Transport May Explain Elevations in Liver Chemistries Observed in Clinical Trials of GGF2 (Cimaglermin Alfa).
    Mosedale M; Button D; Jackson JP; Freeman KM; Brouwer KR; Caggiano AO; Eisen A; Iaci JF; Parry TJ; Stanulis R; Srinivas M; Watkins PB
    Toxicol Sci; 2018 Feb; 161(2):401-411. PubMed ID: 29069498
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Phase I, Single Ascending Dose Study of Cimaglermin Alfa (Neuregulin 1β3) in Patients With Systolic Dysfunction and Heart Failure.
    Lenihan DJ; Anderson SA; Lenneman CG; Brittain E; Muldowney JAS; Mendes L; Zhao PZ; Iaci J; Frohwein S; Zolty R; Eisen A; Sawyer DB; Caggiano AO
    JACC Basic Transl Sci; 2016 Dec; 1(7):576-586. PubMed ID: 30167542
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Refining Liver Safety Risk Assessment: Application of Mechanistic Modeling and Serum Biomarkers to Cimaglermin Alfa (GGF2) Clinical Trials.
    Longo DM; Generaux GT; Howell BA; Siler SQ; Antoine DJ; Button D; Caggiano A; Eisen A; Iaci J; Stanulis R; Parry T; Mosedale M; Watkins PB
    Clin Pharmacol Ther; 2017 Dec; 102(6):961-969. PubMed ID: 28419467
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neuregulin (NRG-1β) Is Pro-Myogenic and Anti-Cachectic in Respiratory Muscles of Post-Myocardial Infarcted Swine.
    Galindo CL; Nguyen VT; Hill B; Easterday E; Cleator JH; Sawyer DB
    Biology (Basel); 2022 Apr; 11(5):. PubMed ID: 35625411
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Neuregulin-1β promotes glucose uptake via PI3K/Akt in neonatal rat cardiomyocytes.
    Pentassuglia L; Heim P; Lebboukh S; Morandi C; Xu L; Brink M
    Am J Physiol Endocrinol Metab; 2016 May; 310(9):E782-94. PubMed ID: 26979522
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neuregulin-1 attenuates development of nephropathy in a type 1 diabetes mouse model with high cardiovascular risk.
    Vandekerckhove L; Vermeulen Z; Liu ZZ; Boimvaser S; Patzak A; Segers VF; De Keulenaer GW
    Am J Physiol Endocrinol Metab; 2016 Apr; 310(7):E495-504. PubMed ID: 26786778
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neuregulin 1 treatment improves glucose tolerance in diabetic db/db mice, but not in healthy mice.
    Ennequin G; Caillaud K; Chavanelle V; Teixeira A; Etienne M; Li X; Boisseau N; Sirvent P
    Arch Physiol Biochem; 2020 Oct; 126(4):320-325. PubMed ID: 30449185
    [No Abstract]   [Full Text] [Related]  

  • 11. In situ postconditioning with neuregulin-1β is mediated by a PI3K/Akt-dependent pathway.
    Ebner B; Lange SA; Hollenbach D; Steinbronn N; Ebner A; Fischaleck C; Braun-Dullaeus R; Weinbrenner C; Strasser RH
    Can J Cardiol; 2015 Jan; 31(1):76-83. PubMed ID: 25547554
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neuregulin 1 improves complex 2-mediated mitochondrial respiration in skeletal muscle of healthy and diabetic mice.
    Ennequin G; Capel F; Caillaud K; Chavanelle V; Etienne M; Teixeira A; Li X; Boisseau N; Sirvent P
    Sci Rep; 2017 May; 7(1):1742. PubMed ID: 28496106
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neuregulin improves response to glucose tolerance test in control and diabetic rats.
    López-Soldado I; Niisuke K; Veiga C; Adrover A; Manzano A; Martínez-Redondo V; Camps M; Bartrons R; Zorzano A; Gumà A
    Am J Physiol Endocrinol Metab; 2016 Mar; 310(6):E440-51. PubMed ID: 26714846
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neuregulins increase mitochondrial oxidative capacity and insulin sensitivity in skeletal muscle cells.
    Cantó C; Pich S; Paz JC; Sanches R; Martínez V; Orpinell M; Palacín M; Zorzano A; Gumà A
    Diabetes; 2007 Sep; 56(9):2185-93. PubMed ID: 17563068
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure.
    Gao R; Zhang J; Cheng L; Wu X; Dong W; Yang X; Li T; Liu X; Xu Y; Li X; Zhou M
    J Am Coll Cardiol; 2010 May; 55(18):1907-14. PubMed ID: 20430261
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Des-aspartate-angiotensin I exerts hypoglycemic action via glucose transporter-4 translocation in type 2 diabetic KKAy mice and GK rats.
    Sim MK; Xu XG; Wong YC; Sim SZ; Lee KO
    Endocrinology; 2007 Dec; 148(12):5925-32. PubMed ID: 17823251
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acute and chronic treatment of ob/ob and db/db mice with AICAR decreases blood glucose concentrations.
    Halseth AE; Ensor NJ; White TA; Ross SA; Gulve EA
    Biochem Biophys Res Commun; 2002 Jun; 294(4):798-805. PubMed ID: 12061777
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chronic Neuregulin-1β Treatment Mitigates the Progression of Postmyocardial Infarction Heart Failure in the Setting of Type 1 Diabetes Mellitus by Suppressing Myocardial Apoptosis, Fibrosis, and Key Oxidant-Producing Enzymes.
    Gupte M; Lal H; Ahmad F; Sawyer DB; Hill MF
    J Card Fail; 2017 Dec; 23(12):887-899. PubMed ID: 28870731
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Association of insulin resistance with hyperglycemia in streptozotocin-diabetic pigs: effects of metformin at isoenergetic feeding in a type 2-like diabetic pig model.
    Koopmans SJ; Mroz Z; Dekker R; Corbijn H; Ackermans M; Sauerwein H
    Metabolism; 2006 Jul; 55(7):960-71. PubMed ID: 16784971
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Diabetic rats and mice are resistant to porcine and human insulin: flawed experimental models for testing islet xenografts.
    Pepper AR; Gall C; Mazzuca DM; Melling CW; White DJ
    Xenotransplantation; 2009; 16(6):502-10. PubMed ID: 20042050
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.