745 related articles for article (PubMed ID: 28790177)
1. Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.
Monahan Z; Ryan VH; Janke AM; Burke KA; Rhoads SN; Zerze GH; O'Meally R; Dignon GL; Conicella AE; Zheng W; Best RB; Cole RN; Mittal J; Shewmaker F; Fawzi NL
EMBO J; 2017 Oct; 36(20):2951-2967. PubMed ID: 28790177
[TBL] [Abstract][Full Text] [Related]
2. The Role of Post-Translational Modifications on Prion-Like Aggregation and Liquid-Phase Separation of FUS.
Rhoads SN; Monahan ZT; Yee DS; Shewmaker FP
Int J Mol Sci; 2018 Mar; 19(3):. PubMed ID: 29547565
[TBL] [Abstract][Full Text] [Related]
3. The prion-like domain of Fused in Sarcoma is phosphorylated by multiple kinases affecting liquid- and solid-phase transitions.
Owen I; Rhoads S; Yee D; Wyne H; Gery K; Hannula I; Sundrum M; Shewmaker F
Mol Biol Cell; 2020 Nov; 31(23):2522-2536. PubMed ID: 32877292
[TBL] [Abstract][Full Text] [Related]
4. The prionlike domain of FUS is multiphosphorylated following DNA damage without altering nuclear localization.
Rhoads SN; Monahan ZT; Yee DS; Leung AY; Newcombe CG; O'Meally RN; Cole RN; Shewmaker FP
Mol Biol Cell; 2018 Aug; 29(15):1786-1797. PubMed ID: 29897835
[TBL] [Abstract][Full Text] [Related]
5. N-terminal acetylation modestly enhances phase separation and reduces aggregation of the low-complexity domain of RNA-binding protein fused in sarcoma.
Bock AS; Murthy AC; Tang WS; Jovic N; Shewmaker F; Mittal J; Fawzi NL
Protein Sci; 2021 Jul; 30(7):1337-1349. PubMed ID: 33547841
[TBL] [Abstract][Full Text] [Related]
6. FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription.
Yamaguchi A; Takanashi K
Sci Rep; 2016 Oct; 6():35195. PubMed ID: 27731383
[TBL] [Abstract][Full Text] [Related]
7. RRM domain of ALS/FTD-causing FUS characteristic of irreversible unfolding spontaneously self-assembles into amyloid fibrils.
Lu Y; Lim L; Song J
Sci Rep; 2017 Apr; 7(1):1043. PubMed ID: 28432364
[TBL] [Abstract][Full Text] [Related]
8. Amyloid-Forming Segment Induces Aggregation of FUS-LC Domain from Phase Separation Modulated by Site-Specific Phosphorylation.
Ding X; Sun F; Chen J; Chen L; Tobin-Miyaji Y; Xue S; Qiang W; Luo SZ
J Mol Biol; 2020 Jan; 432(2):467-483. PubMed ID: 31805282
[TBL] [Abstract][Full Text] [Related]
9. Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation.
Ryan VH; Dignon GL; Zerze GH; Chabata CV; Silva R; Conicella AE; Amaya J; Burke KA; Mittal J; Fawzi NL
Mol Cell; 2018 Feb; 69(3):465-479.e7. PubMed ID: 29358076
[TBL] [Abstract][Full Text] [Related]
10. A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Patel A; Lee HO; Jawerth L; Maharana S; Jahnel M; Hein MY; Stoynov S; Mahamid J; Saha S; Franzmann TM; Pozniakovski A; Poser I; Maghelli N; Royer LA; Weigert M; Myers EW; Grill S; Drechsel D; Hyman AA; Alberti S
Cell; 2015 Aug; 162(5):1066-77. PubMed ID: 26317470
[TBL] [Abstract][Full Text] [Related]
11. FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.
Qamar S; Wang G; Randle SJ; Ruggeri FS; Varela JA; Lin JQ; Phillips EC; Miyashita A; Williams D; Ströhl F; Meadows W; Ferry R; Dardov VJ; Tartaglia GG; Farrer LA; Kaminski Schierle GS; Kaminski CF; Holt CE; Fraser PE; Schmitt-Ulms G; Klenerman D; Knowles T; Vendruscolo M; St George-Hyslop P
Cell; 2018 Apr; 173(3):720-734.e15. PubMed ID: 29677515
[TBL] [Abstract][Full Text] [Related]
12. Insights into the Atomistic Mechanisms of Phosphorylation in Disrupting Liquid-Liquid Phase Separation and Aggregation of the FUS Low-Complexity Domain.
Lao Z; Dong X; Liu X; Li F; Chen Y; Tang Y; Wei G
J Chem Inf Model; 2022 Jul; 62(13):3227-3238. PubMed ID: 35709363
[TBL] [Abstract][Full Text] [Related]
13. Fused in Sarcoma: Properties, Self-Assembly and Correlation with Neurodegenerative Diseases.
Chen C; Ding X; Akram N; Xue S; Luo SZ
Molecules; 2019 Apr; 24(8):. PubMed ID: 31022909
[TBL] [Abstract][Full Text] [Related]
14. Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains.
Murray DT; Kato M; Lin Y; Thurber KR; Hung I; McKnight SL; Tycko R
Cell; 2017 Oct; 171(3):615-627.e16. PubMed ID: 28942918
[TBL] [Abstract][Full Text] [Related]
15. RNA-binding proteins with prion-like domains in health and disease.
Harrison AF; Shorter J
Biochem J; 2017 Apr; 474(8):1417-1438. PubMed ID: 28389532
[TBL] [Abstract][Full Text] [Related]
16. Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II.
Burke KA; Janke AM; Rhine CL; Fawzi NL
Mol Cell; 2015 Oct; 60(2):231-41. PubMed ID: 26455390
[TBL] [Abstract][Full Text] [Related]
17. ALS-causing hPFN1 mutants differentially disrupt LLPS of FUS prion-like domain.
Kang J; Lim L; Song J
Biochem Biophys Res Commun; 2023 Jul; 664():35-42. PubMed ID: 37130459
[TBL] [Abstract][Full Text] [Related]
18. Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models.
Cha SJ; Lee S; Choi HJ; Han YJ; Jeon YM; Jo M; Lee S; Nahm M; Lim SM; Kim SH; Kim HJ; Kim K
Dev Cell; 2022 Mar; 57(6):783-798.e8. PubMed ID: 35320731
[TBL] [Abstract][Full Text] [Related]
19. Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS.
Lee M; Ghosh U; Thurber KR; Kato M; Tycko R
Nat Commun; 2020 Nov; 11(1):5735. PubMed ID: 33184287
[TBL] [Abstract][Full Text] [Related]
20. ATP enhances at low concentrations but dissolves at high concentrations liquid-liquid phase separation (LLPS) of ALS/FTD-causing FUS.
Kang J; Lim L; Song J
Biochem Biophys Res Commun; 2018 Oct; 504(2):545-551. PubMed ID: 30205960
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]