BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 28792759)

  • 1. Effect of Nitrogen Atom Substitution in A
    Azuaje J; Jespers W; Yaziji V; Mallo A; Majellaro M; Caamaño O; Loza MI; Cadavid MI; Brea J; Åqvist J; Sotelo E; Gutiérrez-de-Terán H
    J Med Chem; 2017 Sep; 60(17):7502-7511. PubMed ID: 28792759
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective and potent adenosine A3 receptor antagonists by methoxyaryl substitution on the N-(2,6-diarylpyrimidin-4-yl)acetamide scaffold.
    Yaziji V; Rodríguez D; Coelho A; García-Mera X; El Maatougui A; Brea J; Loza MI; Cadavid MI; Gutiérrez-de-Terán H; Sotelo E
    Eur J Med Chem; 2013 Jan; 59():235-42. PubMed ID: 23231967
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 2-Arylpyrazolo[4,3-d]pyrimidin-7-amino derivatives as new potent and selective human A3 adenosine receptor antagonists. Molecular modeling studies and pharmacological evaluation.
    Squarcialupi L; Colotta V; Catarzi D; Varano F; Filacchioni G; Varani K; Corciulo C; Vincenzi F; Borea PA; Ghelardini C; Di Cesare Mannelli L; Ciancetta A; Moro S
    J Med Chem; 2013 Mar; 56(6):2256-69. PubMed ID: 23427825
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A facile and novel synthesis of N(2)-, C(6)-substituted pyrazolo[3,4-d]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists.
    Venkatesan G; Paira P; Cheong SL; Federico S; Klotz KN; Spalluto G; Pastorin G
    Eur J Med Chem; 2015 Mar; 92():784-98. PubMed ID: 25633494
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacological characterisation of novel adenosine A
    Barkan K; Lagarias P; Stampelou M; Stamatis D; Hoare S; Safitri D; Klotz KN; Vrontaki E; Kolocouris A; Ladds G
    Sci Rep; 2020 Nov; 10(1):20781. PubMed ID: 33247159
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exploring the 7-oxo-thiazolo[5,4-d]pyrimidine core for the design of new human adenosine A3 receptor antagonists. Synthesis, molecular modeling studies and pharmacological evaluation.
    Varano F; Catarzi D; Squarcialupi L; Betti M; Vincenzi F; Ravani A; Varani K; Dal Ben D; Thomas A; Volpini R; Colotta V
    Eur J Med Chem; 2015; 96():105-21. PubMed ID: 25874336
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural refinement of pyrazolo[4,3-d]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A3 adenosine receptor.
    Squarcialupi L; Catarzi D; Varano F; Betti M; Falsini M; Vincenzi F; Ravani A; Ciancetta A; Varani K; Moro S; Colotta V
    Eur J Med Chem; 2016 Jan; 108():117-133. PubMed ID: 26638043
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 5'-C-Ethyl-tetrazolyl-N(6)-substituted adenosine and 2-chloro-adenosine derivatives as highly potent dual acting A1 adenosine receptor agonists and A3 adenosine receptor antagonists.
    Petrelli R; Torquati I; Kachler S; Luongo L; Maione S; Franchetti P; Grifantini M; Novellino E; Lavecchia A; Klotz KN; Cappellacci L
    J Med Chem; 2015 Mar; 58(5):2560-6. PubMed ID: 25699637
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The identification of the 2-phenylphthalazin-1(2H)-one scaffold as a new decorable core skeleton for the design of potent and selective human A3 adenosine receptor antagonists.
    Poli D; Catarzi D; Colotta V; Varano F; Filacchioni G; Daniele S; Trincavelli L; Martini C; Paoletta S; Moro S
    J Med Chem; 2011 Apr; 54(7):2102-13. PubMed ID: 21401121
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Subtle Chemical Changes Cross the Boundary between Agonist and Antagonist: New A
    Lee Y; Hou X; Lee JH; Nayak A; Alexander V; Sharma PK; Chang H; Phan K; Gao ZG; Jacobson KA; Choi S; Jeong LS
    J Med Chem; 2021 Sep; 64(17):12525-12536. PubMed ID: 34435786
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Organoruthenium antagonists of human A₃ adenosine receptors.
    Paira P; Chow MJ; Venkatesan G; Kosaraju VK; Cheong SL; Klotz KN; Ang WH; Pastorin G
    Chemistry; 2013 Jun; 19(25):8321-30. PubMed ID: 23613215
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pyrazin-2(1H)-ones as a novel class of selective A3 adenosine receptor antagonists.
    Azuaje J; Carbajales C; González-Gómez M; Coelho A; Caamaño O; Gutiérrez-de-Terán H; Sotelo E
    Future Med Chem; 2015; 7(11):1373-80. PubMed ID: 26230877
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-Based Optimization of Coumarin hA
    Matos MJ; Vilar S; Vazquez-Rodriguez S; Kachler S; Klotz KN; Buccioni M; Delogu G; Santana L; Uriarte E; Borges F
    J Med Chem; 2020 Mar; 63(5):2577-2587. PubMed ID: 31738058
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New 2-heterocyclyl-imidazo[2,1-i]purin-5-one derivatives as potent and selective human A3 adenosine receptor antagonists.
    Baraldi PG; Preti D; Zaid AN; Saponaro G; Tabrizi MA; Baraldi S; Romagnoli R; Moorman AR; Varani K; Cosconati S; Di Maro S; Marinelli L; Novellino E; Borea PA
    J Med Chem; 2011 Jul; 54(14):5205-20. PubMed ID: 21675777
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists: new insights into structure-affinity relationship and receptor-antagonist recognition.
    Cheong SL; Dolzhenko A; Kachler S; Paoletta S; Federico S; Cacciari B; Dolzhenko A; Klotz KN; Moro S; Spalluto G; Pastorin G
    J Med Chem; 2010 Apr; 53(8):3361-75. PubMed ID: 20307065
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, and binding of homologated truncated 4'-thioadenosine derivatives at the human A3 adenosine receptors.
    Lee HW; Kim HO; Choi WJ; Choi S; Lee JH; Park SG; Yoo L; Jacobson KA; Jeong LS
    Bioorg Med Chem; 2010 Oct; 18(19):7015-21. PubMed ID: 20826090
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-Affinity Relationships and Structure-Kinetics Relationships of Pyrido[2,1-f]purine-2,4-dione Derivatives as Human Adenosine A
    Xia L; Burger WAC; van Veldhoven JPD; Kuiper BJ; van Duijl TT; Lenselink EB; Paasman E; Heitman LH; IJzerman AP
    J Med Chem; 2017 Sep; 60(17):7555-7568. PubMed ID: 28806076
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fragment-Based Discovery of Subtype-Selective Adenosine Receptor Ligands from Homology Models.
    Ranganathan A; Stoddart LA; Hill SJ; Carlsson J
    J Med Chem; 2015 Dec; 58(24):9578-90. PubMed ID: 26592528
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of novel pyrido[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives: potent and selective adenosine A3 receptor antagonists.
    Banda V; Chandrasekaran B; Köse M; Vielmuth C; Müller CE; Chavva K; Gautham SK; Pillalamarri S; Mylavaram R; Akkinepally R; Pamulaparthy S; Banda N
    Arch Pharm (Weinheim); 2013 Oct; 346(10):699-707. PubMed ID: 23996524
    [TBL] [Abstract][Full Text] [Related]  

  • 20. QSAR of adenosine receptor antagonists: Exploring physicochemical requirements for binding of pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives with human adenosine A(3) receptor subtype.
    Pran Kishore D; Balakumar C; Raghuram Rao A; Roy PP; Roy K
    Bioorg Med Chem Lett; 2011 Jan; 21(2):818-23. PubMed ID: 21163647
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.