These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 28800455)

  • 1. In vitro targeting of colon cancer cells using spiropyrazoline oxindoles.
    Nunes RC; Ribeiro CJA; Monteiro Â; Rodrigues CMP; Amaral JD; Santos MMM
    Eur J Med Chem; 2017 Oct; 139():168-179. PubMed ID: 28800455
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of novel spiropyrazoline oxindoles and evaluation of cytotoxicity in cancer cell lines.
    Monteiro Â; Gonçalves LM; Santos MM
    Eur J Med Chem; 2014 May; 79():266-72. PubMed ID: 24747063
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Exploiting the antiproliferative potential of spiropyrazoline oxindoles in a human ovarian cancer cell line.
    Raposo LR; Silva A; Silva D; Roma-Rodrigues C; Espadinha M; Baptista PV; Santos MMM; Fernandes AR
    Bioorg Med Chem; 2021 Jan; 30():115880. PubMed ID: 33348171
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Spirotriazoline oxindoles: A novel chemical scaffold with in vitro anticancer properties.
    Ribeiro CJA; Nunes RC; Amaral JD; Gonçalves LM; Rodrigues CMP; Moreira R; Santos MMM
    Eur J Med Chem; 2017 Nov; 140():494-509. PubMed ID: 28987608
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, combinatorial synthesis and biological evaluations of novel 3-amino-1'-((1-aryl-1H-1,2,3-triazol-5-yl)methyl)-2'-oxospiro[benzo[a] pyrano[2,3-c]phenazine-1,3'-indoline]-2-carbonitrile antitumor hybrid molecules.
    Lu Y; Wang L; Wang X; Xi T; Liao J; Wang Z; Jiang F
    Eur J Med Chem; 2017 Jul; 135():125-141. PubMed ID: 28441581
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of novel antitumor spirotetrahydrothiopyran-oxindole derivatives as potent p53-MDM2 inhibitors.
    Ji C; Wang S; Chen S; He S; Jiang Y; Miao Z; Li J; Sheng C
    Bioorg Med Chem; 2017 Oct; 25(20):5268-5277. PubMed ID: 28797774
    [TBL] [Abstract][Full Text] [Related]  

  • 7. One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells.
    Eldehna WM; El-Naggar DH; Hamed AR; Ibrahim HS; Ghabbour HA; Abdel-Aziz HA
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):309-318. PubMed ID: 29281924
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and biological evaluation of novel steroidal spiro-oxindoles as potent antiproliferative agents.
    Yu B; Shi XJ; Qi PP; Yu DQ; Liu HM
    J Steroid Biochem Mol Biol; 2014 May; 141():121-34. PubMed ID: 24508598
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of New Bis-Spiropyrazoles as Antitumor Agents under Ultrasound Irradiation.
    Abdel Hafez NA; Hassaneen HME; Farghaly TA; Riyadh SM; Elzahabi HSA
    Mini Rev Med Chem; 2018; 18(7):631-637. PubMed ID: 28901853
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and in vitro evaluation of novel spiroketopyrazoles as acetyl-CoA carboxylase inhibitors and potential antitumor agents.
    Huang T; Wu X; Yan S; Liu T; Yin X
    Eur J Med Chem; 2021 Feb; 212():113036. PubMed ID: 33276990
    [TBL] [Abstract][Full Text] [Related]  

  • 11. H2O-mediated isatin spiro-epoxide ring opening with NaCN: Synthesis of novel 3-tetrazolylmethyl-3-hydroxy-oxindole hybrids and their anticancer evaluation.
    Sharma P; Senwar KR; Jeengar MK; Reddy TS; Naidu VG; Kamal A; Shankaraiah N
    Eur J Med Chem; 2015 Nov; 104():11-24. PubMed ID: 26413726
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, Synthesis, and Biological Evaluation of Novel Thiazolyl Substituted Bis-pyrazole Oxime Derivatives with Potent Antitumor Activities by Selectively Inducing Apoptosis and ROS in Cancer Cells.
    Xiong B; Chen S; Zhu P; Huang M; Gao W; Zhu R; Qian J; Peng Y; Zhang Y; Dai H; Ling Y
    Med Chem; 2019; 15(7):743-754. PubMed ID: 30147012
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular hybridization design and synthesis of novel spirooxindole-based MDM2 inhibitors endowed with BCL2 signaling attenuation; a step towards the next generation p53 activators.
    Lotfy G; Abdel Aziz YM; Said MM; El Ashry ESH; El Tamany ESH; Abu-Serie MM; Teleb M; Dömling A; Barakat A
    Bioorg Chem; 2021 Dec; 117():105427. PubMed ID: 34794098
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dithiocarbamation of spiro-aziridine oxindoles: a facile access to C3-functionalised 3-thiooxindoles as apoptosis inducing agents.
    Sakla AP; Panda B; Laxmikeshav K; Soni JP; Bhandari S; Godugu C; Shankaraiah N
    Org Biomol Chem; 2021 Dec; 19(48):10622-10634. PubMed ID: 34870311
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of Spiro[indole-3,5'-isoxazoles] with Anticancer Activity via a Formal [4 + 1]-Spirocyclization of Nitroalkenes to Indoles.
    Aksenov AV; Aksenov DA; Arutiunov NA; Aksenov NA; Aleksandrova EV; Zhao Z; Du L; Kornienko A; Rubin M
    J Org Chem; 2019 Jun; 84(11):7123-7137. PubMed ID: 31070030
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.
    Ding K; Lu Y; Nikolovska-Coleska Z; Wang G; Qiu S; Shangary S; Gao W; Qin D; Stuckey J; Krajewski K; Roller PP; Wang S
    J Med Chem; 2006 Jun; 49(12):3432-5. PubMed ID: 16759082
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of spiro[cyclopropane-1,3'-indolin]-2'-ones as potential anticancer agents.
    Reddy CN; Nayak VL; Mani GS; Kapure JS; Adiyala PR; Maurya RA; Kamal A
    Bioorg Med Chem Lett; 2015 Oct; 25(20):4580-6. PubMed ID: 26330077
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Spiro[pyrrolidine-3, 3´-oxindole] as potent anti-breast cancer compounds: Their design, synthesis, biological evaluation and cellular target identification.
    Hati S; Tripathy S; Dutta PK; Agarwal R; Srinivasan R; Singh A; Singh S; Sen S
    Sci Rep; 2016 Aug; 6():32213. PubMed ID: 27573798
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of new thiazolo-pyrrolidine-(spirooxindole) tethered to 3-acylindole as anticancer agents.
    Islam MS; Ghawas HM; El-Senduny FF; Al-Majid AM; Elshaier YAMM; Badria FA; Barakat A
    Bioorg Chem; 2019 Feb; 82():423-430. PubMed ID: 30508794
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and Characterization of a New Benzoindole Derivative with Apoptotic Activity Against Colon Cancer Cells.
    Hajiaghaalipour F; Faraj FL; Bagheri E; Ali HM; Abdulla MA; Majid NA
    Curr Pharm Des; 2017; 23(41):6358-6365. PubMed ID: 28325143
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.