These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 28802254)

  • 1. TDP1 is Critical for the Repair of DNA Breaks Induced by Sapacitabine, a Nucleoside also Targeting ATM- and BRCA-Deficient Tumors.
    Al Abo M; Sasanuma H; Liu X; Rajapakse VN; Huang SY; Kiselev E; Takeda S; Plunkett W; Pommier Y
    Mol Cancer Ther; 2017 Nov; 16(11):2543-2551. PubMed ID: 28802254
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting BRCA1/2 deficient ovarian cancer with CNDAC-based drug combinations.
    Liu X; Jiang Y; Nowak B; Qiang B; Cheng N; Chen Y; Plunkett W
    Cancer Chemother Pharmacol; 2018 Feb; 81(2):255-267. PubMed ID: 29189915
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sapacitabine, the prodrug of CNDAC, is a nucleoside analog with a unique action mechanism of inducing DNA strand breaks.
    Liu XJ; Nowak B; Wang YQ; Plunkett W
    Chin J Cancer; 2012 Aug; 31(8):373-80. PubMed ID: 22739266
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism-Based Drug Combinations with the DNA Strand-Breaking Nucleoside Analog CNDAC.
    Liu X; Jiang Y; Nowak B; Hargis S; Plunkett W
    Mol Cancer Ther; 2016 Oct; 15(10):2302-2313. PubMed ID: 27474148
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Homologous recombination as a resistance mechanism to replication-induced double-strand breaks caused by the antileukemia agent CNDAC.
    Liu X; Wang Y; Benaissa S; Matsuda A; Kantarjian H; Estrov Z; Plunkett W
    Blood; 2010 Sep; 116(10):1737-46. PubMed ID: 20479284
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TDP1 and PARP1 deficiency are cytotoxic to rhabdomyosarcoma cells.
    Fam HK; Walton C; Mitra SA; Chowdhury M; Osborne N; Choi K; Sun G; Wong PC; O'Sullivan MJ; Turashvili G; Aparicio S; Triche TJ; Bond M; Pallen CJ; Boerkoel CF
    Mol Cancer Res; 2013 Oct; 11(10):1179-92. PubMed ID: 23913164
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Repair of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair.
    Wang Y; Liu X; Matsuda A; Plunkett W
    Cancer Res; 2008 May; 68(10):3881-9. PubMed ID: 18483273
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sapacitabine for cancer.
    Liu X; Kantarjian H; Plunkett W
    Expert Opin Investig Drugs; 2012 Apr; 21(4):541-55. PubMed ID: 22329458
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PARP1-TDP1 coupling for the repair of topoisomerase I-induced DNA damage.
    Das BB; Huang SY; Murai J; Rehman I; Amé JC; Sengupta S; Das SK; Majumdar P; Zhang H; Biard D; Majumder HK; Schreiber V; Pommier Y
    Nucleic Acids Res; 2014 Apr; 42(7):4435-49. PubMed ID: 24493735
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells.
    Murai J; Huang SY; Das BB; Dexheimer TS; Takeda S; Pommier Y
    J Biol Chem; 2012 Apr; 287(16):12848-57. PubMed ID: 22375014
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tdp1 processes chromate-induced single-strand DNA breaks that collapse replication forks.
    Ganguly A; Guo L; Sun L; Suo F; Du LL; Russell P
    PLoS Genet; 2018 Aug; 14(8):e1007595. PubMed ID: 30148840
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumor activity and novel DNA-self-strand-breaking mechanism of CNDAC (1-(2-C-cyano-2-deoxy-beta-D-arabino-pentofuranosyl) cytosine) and its N4-palmitoyl derivative (CS-682).
    Hanaoka K; Suzuki M; Kobayashi T; Tanzawa F; Tanaka K; Shibayama T; Miura S; Ikeda T; Iwabuchi H; Nakagawa A; Mitsuhashi Y; Hisaoka M; Kaneko M; Tomida A; Wataya Y; Nomura T; Sasaki T; Matsuda A; Tsuruo T; Kurakata S
    Int J Cancer; 1999 Jul; 82(2):226-36. PubMed ID: 10389757
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Repair of DNA damage induced by the novel nucleoside analogue CNDAG through homologous recombination.
    Liu X; Jiang Y; Nowak B; Ichikawa S; Ohtawa M; Matsuda A; Plunkett W
    Cancer Chemother Pharmacol; 2020 Apr; 85(4):661-672. PubMed ID: 32072218
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ataxia-telangiectasia and Rad3-related and DNA-dependent protein kinase cooperate in G2 checkpoint activation by the DNA strand-breaking nucleoside analogue 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine.
    Liu X; Matsuda A; Plunkett W
    Mol Cancer Ther; 2008 Jan; 7(1):133-42. PubMed ID: 18202016
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1.
    Liu C; Pouliot JJ; Nash HA
    Proc Natl Acad Sci U S A; 2002 Nov; 99(23):14970-5. PubMed ID: 12397185
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nucleosides and nucleotides. 141. Chemical stability of a new antitumor nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine in alkaline medium: formation of 2'-C-cyano-2'-deoxy-1-beta-D-ribo-pentofuranosylcytosine and its antitumor activity.
    Azuma A; Hanaoka K; Kurihara A; Kobayashi T; Miyauchi S; Kamo N; Tanaka M; Sasaki T; Matsuda A
    J Med Chem; 1995 Aug; 38(17):3391-7. PubMed ID: 7650692
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tyrosyl-DNA phosphodiesterase 2 (TDP2) repairs topoisomerase 1 DNA-protein crosslinks and 3'-blocking lesions in the absence of tyrosyl-DNA phosphodiesterase 1 (TDP1).
    Tsuda M; Kitamasu K; Kumagai C; Sugiyama K; Nakano T; Ide H
    DNA Repair (Amst); 2020; 91-92():102849. PubMed ID: 32460231
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.
    Zeng Z; Sharma A; Ju L; Murai J; Umans L; Vermeire L; Pommier Y; Takeda S; Huylebroeck D; Caldecott KW; El-Khamisy SF
    Nucleic Acids Res; 2012 Sep; 40(17):8371-80. PubMed ID: 22740648
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine: a novel anticancer nucleoside analog that causes both DNA strand breaks and G(2) arrest.
    Azuma A; Huang P; Matsuda A; Plunkett W
    Mol Pharmacol; 2001 Apr; 59(4):725-31. PubMed ID: 11259616
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin.
    El-Khamisy SF; Katyal S; Patel P; Ju L; McKinnon PJ; Caldecott KW
    DNA Repair (Amst); 2009 Jun; 8(6):760-6. PubMed ID: 19303373
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.