146 related articles for article (PubMed ID: 28803992)
1. P-REX1 amplification promotes progression of cutaneous melanoma via the PAK1/P38/MMP-2 pathway.
Wang J; Hirose H; Du G; Chong K; Kiyohara E; Witz IP; Hoon DSB
Cancer Lett; 2017 Oct; 407():66-75. PubMed ID: 28803992
[TBL] [Abstract][Full Text] [Related]
2. Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis.
Qin J; Xie Y; Wang B; Hoshino M; Wolff DW; Zhao J; Scofield MA; Dowd FJ; Lin MF; Tu Y
Oncogene; 2009 Apr; 28(16):1853-63. PubMed ID: 19305425
[TBL] [Abstract][Full Text] [Related]
3. P-REX1 creates a positive feedback loop to activate growth factor receptor, PI3K/AKT and MEK/ERK signaling in breast cancer.
Dillon LM; Bean JR; Yang W; Shee K; Symonds LK; Balko JM; McDonald WH; Liu S; Gonzalez-Angulo AM; Mills GB; Arteaga CL; Miller TW
Oncogene; 2015 Jul; 34(30):3968-76. PubMed ID: 25284585
[TBL] [Abstract][Full Text] [Related]
4. Phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 (P-Rex-1), a guanine nucleotide exchange factor for Rac, mediates angiogenic responses to stromal cell-derived factor-1/chemokine stromal cell derived factor-1 (SDF-1/CXCL-12) linked to Rac activation, endothelial cell migration, and in vitro angiogenesis.
Carretero-Ortega J; Walsh CT; Hernández-García R; Reyes-Cruz G; Brown JH; Vázquez-Prado J
Mol Pharmacol; 2010 Mar; 77(3):435-42. PubMed ID: 20018810
[TBL] [Abstract][Full Text] [Related]
5. P-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironments.
Campbell AD; Lawn S; McGarry LC; Welch HC; Ozanne BW; Norman JC
PLoS One; 2013; 8(1):e53982. PubMed ID: 23382862
[TBL] [Abstract][Full Text] [Related]
6. P-Rex1 is required for efficient melanoblast migration and melanoma metastasis.
Lindsay CR; Lawn S; Campbell AD; Faller WJ; Rambow F; Mort RL; Timpson P; Li A; Cammareri P; Ridgway RA; Morton JP; Doyle B; Hegarty S; Rafferty M; Murphy IG; McDermott EW; Sheahan K; Pedone K; Finn AJ; Groben PA; Thomas NE; Hao H; Carson C; Norman JC; Machesky LM; Gallagher WM; Jackson IJ; Van Kempen L; Beermann F; Der C; Larue L; Welch HC; Ozanne BW; Sansom OJ
Nat Commun; 2011 Nov; 2():555. PubMed ID: 22109529
[TBL] [Abstract][Full Text] [Related]
7. Ovostatin 2 knockdown significantly inhibits the growth, migration, and tumorigenicity of cutaneous malignant melanoma cells.
Huang YX; Song H; Tao Y; Shao XB; Zeng XS; Xu XL; Qi JL; Sun JF
PLoS One; 2018; 13(4):e0195610. PubMed ID: 29684087
[TBL] [Abstract][Full Text] [Related]
8. P-REX1, a Rac guanine exchange factor, links melanocyte development and melanoma progression.
Walker G
Pigment Cell Melanoma Res; 2011 Dec; 24(6):1086-7. PubMed ID: 22216451
[No Abstract] [Full Text] [Related]
9. Activated mutant NRas(Q61K) drives aberrant melanocyte signaling, survival, and invasiveness via a Rac1-dependent mechanism.
Li A; Ma Y; Jin M; Mason S; Mort RL; Blyth K; Larue L; Sansom OJ; Machesky LM
J Invest Dermatol; 2012 Nov; 132(11):2610-21. PubMed ID: 22718121
[TBL] [Abstract][Full Text] [Related]
10. P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration.
Hernández-Negrete I; Carretero-Ortega J; Rosenfeldt H; Hernández-García R; Calderón-Salinas JV; Reyes-Cruz G; Gutkind JS; Vázquez-Prado J
J Biol Chem; 2007 Aug; 282(32):23708-15. PubMed ID: 17565979
[TBL] [Abstract][Full Text] [Related]
11. P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.
Damoulakis G; Gambardella L; Rossman KL; Lawson CD; Anderson KE; Fukui Y; Welch HC; Der CJ; Stephens LR; Hawkins PT
J Cell Sci; 2014 Jun; 127(Pt 11):2589-600. PubMed ID: 24659802
[TBL] [Abstract][Full Text] [Related]
12. The novel prognostic marker SPOCK2 regulates tumour progression in melanoma.
Kang JY; Cho H; Gil M; Lee H; Park S; Kim KE
Exp Dermatol; 2024 Jun; 33(6):e15092. PubMed ID: 38888196
[TBL] [Abstract][Full Text] [Related]
13. PtdIns(3,4,5)P
Srijakotre N; Liu HJ; Nobis M; Man J; Yip HYK; Papa A; Abud HE; Anderson KI; Welch HCE; Tiganis T; Timpson P; McLean CA; Ooms LM; Mitchell CA
Proc Natl Acad Sci U S A; 2020 Nov; 117(45):28056-28067. PubMed ID: 33097662
[TBL] [Abstract][Full Text] [Related]
14. Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.
Pan D; Barber MA; Hornigold K; Baker MJ; Toth JM; Oxley D; Welch HC
J Biol Chem; 2016 Mar; 291(12):6359-75. PubMed ID: 26792863
[TBL] [Abstract][Full Text] [Related]
15. Constitutive RAC activation is not sufficient to initiate melanocyte neoplasia but accelerates malignant progression.
Dalton LE; Kamarashev J; Barinaga-Rementeria Ramirez I; White G; Malliri A; Hurlstone A
J Invest Dermatol; 2013 Jun; 133(6):1572-81. PubMed ID: 23337888
[TBL] [Abstract][Full Text] [Related]
16. The increased expression of Y box-binding protein 1 in melanoma stimulates proliferation and tumor invasion, antagonizes apoptosis and enhances chemoresistance.
Schittek B; Psenner K; Sauer B; Meier F; Iftner T; Garbe C
Int J Cancer; 2007 May; 120(10):2110-8. PubMed ID: 17266041
[TBL] [Abstract][Full Text] [Related]
17. FGFR3 promotes the growth and malignancy of melanoma by influencing EMT and the phosphorylation of ERK, AKT, and EGFR.
Li L; Zhang S; Li H; Chou H
BMC Cancer; 2019 Oct; 19(1):963. PubMed ID: 31619201
[TBL] [Abstract][Full Text] [Related]
18. The Rho guanine nucleotide exchange factor P-Rex1 as a potential drug target for cancer metastasis and inflammatory diseases.
Ye RD
Pharmacol Res; 2020 Mar; 153():104676. PubMed ID: 32006571
[TBL] [Abstract][Full Text] [Related]
19. cAMP-dependent activation of the Rac guanine exchange factor P-REX1 by type I protein kinase A (PKA) regulatory subunits.
Adame-García SR; Cervantes-Villagrana RD; Orduña-Castillo LB; Del Rio JC; Gutkind JS; Reyes-Cruz G; Taylor SS; Vázquez-Prado J
J Biol Chem; 2019 Feb; 294(7):2232-2246. PubMed ID: 30530493
[TBL] [Abstract][Full Text] [Related]
20. RASSF8 regulates progression of cutaneous melanoma through nuclear factor-κb.
Wang J; Hua W; Huang SK; Fan K; Takeshima L; Mao Y; Hoon DS
Oncotarget; 2015 Oct; 6(30):30165-77. PubMed ID: 26334503
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]