BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

475 related articles for article (PubMed ID: 28806139)

  • 1. Mask mitigates MAPT- and FUS-induced degeneration by enhancing autophagy through lysosomal acidification.
    Zhu M; Zhang S; Tian X; Wu C
    Autophagy; 2017; 13(11):1924-1938. PubMed ID: 28806139
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau).
    Xu Y; Zhang S; Zheng H
    Autophagy; 2019 Apr; 15(4):583-598. PubMed ID: 30290707
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress.
    Chambraud B; Daguinot C; Guillemeau K; Genet M; Dounane O; Meduri G; Poüs C; Baulieu EE; Giustiniani J
    Autophagy; 2021 Nov; 17(11):3491-3510. PubMed ID: 33459145
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Drosophila Mitf regulates the V-ATPase and the lysosomal-autophagic pathway.
    Bouché V; Espinosa AP; Leone L; Sardiello M; Ballabio A; Botas J
    Autophagy; 2016; 12(3):484-98. PubMed ID: 26761346
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS.
    Pandey UB; Nie Z; Batlevi Y; McCray BA; Ritson GP; Nedelsky NB; Schwartz SL; DiProspero NA; Knight MA; Schuldiner O; Padmanabhan R; Hild M; Berry DL; Garza D; Hubbert CC; Yao TP; Baehrecke EH; Taylor JP
    Nature; 2007 Jun; 447(7146):859-63. PubMed ID: 17568747
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo.
    Gogia N; Sarkar A; Mehta AS; Ramesh N; Deshpande P; Kango-Singh M; Pandey UB; Singh A
    Neurobiol Dis; 2020 Jul; 140():104837. PubMed ID: 32199908
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies.
    Akwa Y; Di Malta C; Zallo F; Gondard E; Lunati A; Diaz-de-Grenu LZ; Zampelli A; Boiret A; Santamaria S; Martinez-Preciado M; Cortese K; Kordower JH; Matute C; Lozano AM; Capetillo-Zarate E; Vaccari T; Settembre C; Baulieu EE; Tampellini D
    Autophagy; 2023 Feb; 19(2):660-677. PubMed ID: 35867714
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.
    Ciechanover A; Kwon YT
    Exp Mol Med; 2015 Mar; 47(3):e147. PubMed ID: 25766616
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.
    Feng Q; Luo Y; Zhang XN; Yang XF; Hong XY; Sun DS; Li XC; Hu Y; Li XG; Zhang JF; Li X; Yang Y; Wang Q; Liu GP; Wang JZ
    Autophagy; 2020 Apr; 16(4):641-658. PubMed ID: 31223056
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The emerging roles of vacuolar-type ATPase-dependent Lysosomal acidification in neurodegenerative diseases.
    Song Q; Meng B; Xu H; Mao Z
    Transl Neurodegener; 2020 May; 9(1):17. PubMed ID: 32393395
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion.
    Xia Q; Wang H; Hao Z; Fu C; Hu Q; Gao F; Ren H; Chen D; Han J; Ying Z; Wang G
    EMBO J; 2016 Jan; 35(2):121-42. PubMed ID: 26702100
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing.
    Wang Y; Martinez-Vicente M; Krüger U; Kaushik S; Wong E; Mandelkow EM; Cuervo AM; Mandelkow E
    Hum Mol Genet; 2009 Nov; 18(21):4153-70. PubMed ID: 19654187
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reduced expression of dMyc mitigates Tau
    Pragati ; Chanu SI; Sarkar S
    Neurosci Lett; 2020 Jan; 715():134622. PubMed ID: 31715291
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion.
    Mauvezin C; Neufeld TP
    Autophagy; 2015; 11(8):1437-8. PubMed ID: 26156798
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Parkin expression reverses mitochondrial dysfunction in fused in sarcoma-induced amyotrophic lateral sclerosis.
    Cha SJ; Choi HJ; Kim HJ; Choi EJ; Song KH; Im DS; Kim K
    Insect Mol Biol; 2020 Feb; 29(1):56-65. PubMed ID: 31290213
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reduction of spermine synthase enhances autophagy to suppress Tau accumulation.
    Tao X; Liu J; Diaz-Perez Z; Foley JR; Nwafor A; Stewart TM; Casero RA; Zhai RG
    Cell Death Dis; 2024 May; 15(5):333. PubMed ID: 38740758
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thioridazine reverts the phenotype in cellular and Drosophila models of amyotrophic lateral sclerosis by enhancing TDP-43 aggregate clearance.
    Cragnaz L; Spinelli G; De Conti L; Bureau EA; Brownlees J; Feiguin F; Romano V; Skoko N; Klima R; Kettleborough CA; Baralle FE; Baralle M
    Neurobiol Dis; 2021 Dec; 160():105515. PubMed ID: 34571136
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pur-alpha functionally interacts with FUS carrying ALS-associated mutations.
    Di Salvio M; Piccinni V; Gerbino V; Mantoni F; Camerini S; Lenzi J; Rosa A; Chellini L; Loreni F; Carrì MT; Bozzoni I; Cozzolino M; Cestra G
    Cell Death Dis; 2015 Oct; 6(10):e1943. PubMed ID: 26492376
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Traumatic injury induces stress granule formation and enhances motor dysfunctions in ALS/FTD models.
    Anderson EN; Gochenaur L; Singh A; Grant R; Patel K; Watkins S; Wu JY; Pandey UB
    Hum Mol Genet; 2018 Apr; 27(8):1366-1381. PubMed ID: 29432563
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of ter94, Drosophila VCP, as a strong modulator of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS.
    Azuma Y; Tokuda T; Shimamura M; Kyotani A; Sasayama H; Yoshida T; Mizuta I; Mizuno T; Nakagawa M; Fujikake N; Ueyama M; Nagai Y; Yamaguchi M
    Hum Mol Genet; 2014 Jul; 23(13):3467-80. PubMed ID: 24497576
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.