BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 28820388)

  • 1. Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy.
    Li X; Wu Z; An X; Mei Q; Bai M; Hanski L; Li X; Ahola T; Han W
    Elife; 2017 Aug; 6():. PubMed ID: 28820388
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling.
    Wu G; Song L; Zhu J; Hu Y; Cao L; Tan Z; Zhang S; Li Z; Li J
    Cancer Res; 2018 Nov; 78(22):6399-6412. PubMed ID: 30254148
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LRP16 integrates into NF-κB transcriptional complex and is required for its functional activation.
    Wu Z; Li Y; Li X; Ti D; Zhao Y; Si Y; Mei Q; Zhao P; Fu X; Han W
    PLoS One; 2011 Mar; 6(3):e18157. PubMed ID: 21483817
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation.
    Farabaugh KT; Krokowski D; Guan BJ; Gao Z; Gao XH; Wu J; Jobava R; Ray G; de Jesus TJ; Bianchi MG; Chukwurah E; Bussolati O; Kilberg M; Buchner DA; Sen GC; Cotton C; McDonald C; Longworth M; Ramakrishnan P; Hatzoglou M
    Elife; 2020 Mar; 9():. PubMed ID: 32175843
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-κB activation.
    Fu K; Sun X; Wier EM; Hodgson A; Liu Y; Sears CL; Wan F
    Elife; 2016 Jul; 5():. PubMed ID: 27458801
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An LRP16-containing preassembly complex contributes to NF-κB activation induced by DNA double-strand breaks.
    Wu Z; Wang C; Bai M; Li X; Mei Q; Li X; Wang Y; Fu X; Luo G; Han W
    Nucleic Acids Res; 2015 Mar; 43(6):3167-79. PubMed ID: 25735744
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The N-terminus of PKR is responsible for the activation of the NF-kappaB signaling pathway by interacting with the IKK complex.
    Bonnet MC; Daurat C; Ottone C; Meurs EF
    Cell Signal; 2006 Nov; 18(11):1865-75. PubMed ID: 16600570
    [TBL] [Abstract][Full Text] [Related]  

  • 8. KINK-1, a novel small-molecule inhibitor of IKKbeta, and the susceptibility of melanoma cells to antitumoral treatment.
    Schön M; Wienrich BG; Kneitz S; Sennefelder H; Amschler K; Vöhringer V; Weber O; Stiewe T; Ziegelbauer K; Schön MP
    J Natl Cancer Inst; 2008 Jun; 100(12):862-75. PubMed ID: 18544741
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Concurrent blockade of the NF-kappaB and Akt pathways potently sensitizes cancer cells to chemotherapeutic-induced cytotoxicity.
    He HN; Wang X; Zheng XL; Sun H; Shi XW; Zhong YJ; Huang B; Yang L; Li JK; Liao LC; Zhang L; Hu LN; Lin Y
    Cancer Lett; 2010 Sep; 295(1):38-43. PubMed ID: 20207071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothe cin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-kappaB activation.
    Cusack JC; Liu R; Baldwin AS
    Cancer Res; 2000 May; 60(9):2323-30. PubMed ID: 10811101
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Co-inhibition of BET proteins and NF-κB as a potential therapy for colorectal cancer through synergistic inhibiting MYC and FOXM1 expressions.
    Wu T; Wang G; Chen W; Zhu Z; Liu Y; Huang Z; Huang Y; Du P; Yang Y; Liu CY; Cui L
    Cell Death Dis; 2018 Feb; 9(3):315. PubMed ID: 29472532
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Correction: Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy.
    Li X; Wu Z; An X; Mei Q; Bai M; Hanski L; Li X; Ahola T; Han W
    Elife; 2020 Apr; 9():. PubMed ID: 32297858
    [No Abstract]   [Full Text] [Related]  

  • 13. Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.
    Takada Y; Ichikawa H; Pataer A; Swisher S; Aggarwal BB
    Oncogene; 2007 Feb; 26(8):1201-12. PubMed ID: 16924232
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutations of p53 and KRAS activate NF-κB to promote chemoresistance and tumorigenesis via dysregulation of cell cycle and suppression of apoptosis in lung cancer cells.
    Yang L; Zhou Y; Li Y; Zhou J; Wu Y; Cui Y; Yang G; Hong Y
    Cancer Lett; 2015 Feb; 357(2):520-6. PubMed ID: 25499080
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NF-kappaB inhibition through proteasome inhibition or IKKbeta blockade increases the susceptibility of melanoma cells to cytostatic treatment through distinct pathways.
    Amschler K; Schön MP; Pletz N; Wallbrecht K; Erpenbeck L; Schön M
    J Invest Dermatol; 2010 Apr; 130(4):1073-86. PubMed ID: 19940859
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Concurrent blockade of NF-κB and Akt pathways potentiates cisplatin's antitumor activity in vivo.
    Sun H; Zheng X; Wang Q; Yan J; Li D; Zhou Y; Lin Y; Zhang L; Wang X
    Anticancer Drugs; 2012 Nov; 23(10):1039-46. PubMed ID: 22760211
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antiapoptotic effect of serum and glucocorticoid-inducible protein kinase is mediated by novel mechanism activating I{kappa}B kinase.
    Zhang L; Cui R; Cheng X; Du J
    Cancer Res; 2005 Jan; 65(2):457-64. PubMed ID: 15695387
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prolyl hydroxylase-3 is down-regulated in colorectal cancer cells and inhibits IKKbeta independent of hydroxylase activity.
    Xue J; Li X; Jiao S; Wei Y; Wu G; Fang J
    Gastroenterology; 2010 Feb; 138(2):606-15. PubMed ID: 19786027
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.
    Gil J; Rullas J; García MA; Alcamí J; Esteban M
    Oncogene; 2001 Jan; 20(3):385-94. PubMed ID: 11313968
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NF-κB and Poly (ADP-ribose) Polymerase 1 Form a Positive Feedback Loop that Regulates DNA Repair in Acute Myeloid Leukemia Cells.
    Li D; Luo Y; Chen X; Zhang L; Wang T; Zhuang Y; Fan Y; Xu J; Chen Y; Wu L
    Mol Cancer Res; 2019 Mar; 17(3):761-772. PubMed ID: 30559256
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.