323 related articles for article (PubMed ID: 28821541)
1. Targeting miR-423-5p Reverses Exercise Training-Induced HCN4 Channel Remodeling and Sinus Bradycardia.
D'Souza A; Pearman CM; Wang Y; Nakao S; Logantha SJRJ; Cox C; Bennett H; Zhang Y; Johnsen AB; Linscheid N; Poulsen PC; Elliott J; Coulson J; McPhee J; Robertson A; da Costa Martins PA; Kitmitto A; Wisløff U; Cartwright EJ; Monfredi O; Lundby A; Dobrzynski H; Oceandy D; Morris GM; Boyett MR
Circ Res; 2017 Oct; 121(9):1058-1068. PubMed ID: 28821541
[TBL] [Abstract][Full Text] [Related]
2. Exercise training reduces resting heart rate via downregulation of the funny channel HCN4.
D'Souza A; Bucchi A; Johnsen AB; Logantha SJ; Monfredi O; Yanni J; Prehar S; Hart G; Cartwright E; Wisloff U; Dobryznski H; DiFrancesco D; Morris GM; Boyett MR
Nat Commun; 2014 May; 5():3775. PubMed ID: 24825544
[TBL] [Abstract][Full Text] [Related]
3. Genetic Ablation of G Protein-Gated Inwardly Rectifying K
Bidaud I; D'Souza A; Forte G; Torre E; Greuet D; Thirard S; Anderson C; Chung You Chong A; Torrente AG; Roussel J; Wickman K; Boyett MR; Mangoni ME; Mesirca P
Front Physiol; 2020; 11():519382. PubMed ID: 33551824
[No Abstract] [Full Text] [Related]
4. Silencing miR-370-3p rescues funny current and sinus node function in heart failure.
Yanni J; D'Souza A; Wang Y; Li N; Hansen BJ; Zakharkin SO; Smith M; Hayward C; Whitson BA; Mohler PJ; Janssen PML; Zeef L; Choudhury M; Zi M; Cai X; Logantha SJRJ; Nakao S; Atkinson A; Petkova M; Doris U; Ariyaratnam J; Cartwright EJ; Griffiths-Jones S; Hart G; Fedorov VV; Oceandy D; Dobrzynski H; Boyett MR
Sci Rep; 2020 Jul; 10(1):11279. PubMed ID: 32647133
[TBL] [Abstract][Full Text] [Related]
5. Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated with familial asymptomatic sinus bradycardia.
Nof E; Luria D; Brass D; Marek D; Lahat H; Reznik-Wolf H; Pras E; Dascal N; Eldar M; Glikson M
Circulation; 2007 Jul; 116(5):463-70. PubMed ID: 17646576
[TBL] [Abstract][Full Text] [Related]
6. A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate.
D'Souza A; Wang Y; Anderson C; Bucchi A; Baruscotti M; Olieslagers S; Mesirca P; Johnsen AB; Mastitskaya S; Ni H; Zhang Y; Black N; Cox C; Wegner S; Bano-Otalora B; Petit C; Gill E; Logantha SJRJ; Dobrzynski H; Ashton N; Hart G; Zhang R; Zhang H; Cartwright EJ; Wisloff U; Mangoni ME; da Costa Martins PA; Piggins HD; DiFrancesco D; Boyett MR
Heart Rhythm; 2021 May; 18(5):801-810. PubMed ID: 33278629
[TBL] [Abstract][Full Text] [Related]
7. Disease-associated HCN4 V759I variant is not sufficient to impair cardiac pacemaking.
Erlenhardt N; Kletke O; Wohlfarth F; Komadowski MA; Clasen L; Makimoto H; Rinné S; Kelm M; Jungen C; Decher N; Meyer C; Klöcker N
Pflugers Arch; 2020 Dec; 472(12):1733-1742. PubMed ID: 33095298
[TBL] [Abstract][Full Text] [Related]
8. Identification of Key Small Non-Coding MicroRNAs Controlling Pacemaker Mechanisms in the Human Sinus Node.
Petkova M; Atkinson AJ; Yanni J; Stuart L; Aminu AJ; Ivanova AD; Pustovit KB; Geragthy C; Feather A; Li N; Zhang Y; Oceandy D; Perde F; Molenaar P; D'Souza A; Fedorov VV; Dobrzynski H
J Am Heart Assoc; 2020 Oct; 9(20):e016590. PubMed ID: 33059532
[TBL] [Abstract][Full Text] [Related]
9. Sinus node dysfunction and hyperpolarization-activated (HCN) channel subunit remodeling in a canine heart failure model.
Zicha S; Fernández-Velasco M; Lonardo G; L'Heureux N; Nattel S
Cardiovasc Res; 2005 Jun; 66(3):472-81. PubMed ID: 15914112
[TBL] [Abstract][Full Text] [Related]
10. β1-Adrenergic blocker bisoprolol reverses down-regulated ion channels in sinoatrial node of heart failure rats.
Du Y; Zhang J; Xi Y; Wu G; Han K; Huang X; Ma A; Wang T
J Physiol Biochem; 2016 Jun; 72(2):293-302. PubMed ID: 26995749
[TBL] [Abstract][Full Text] [Related]
11. Mitochondrial thioredoxin-2 maintains HCN4 expression and prevents oxidative stress-mediated sick sinus syndrome.
Yang B; Huang Y; Zhang H; Huang Y; Zhou HJ; Young L; Xiao H; Min W
J Mol Cell Cardiol; 2020 Jan; 138():291-303. PubMed ID: 31751569
[TBL] [Abstract][Full Text] [Related]
12. HCN4 mutation as a molecular explanation on patients with bradycardia and non-compaction cardiomyopathy.
Millat G; Janin A; de Tauriac O; Roux A; Dauphin C
Eur J Med Genet; 2015 Sep; 58(9):439-42. PubMed ID: 26206080
[TBL] [Abstract][Full Text] [Related]
13. A mutant HCN4 channel in a family with bradycardia, left bundle branch block, and left ventricular noncompaction.
Yokoyama R; Kinoshita K; Hata Y; Abe M; Matsuoka K; Hirono K; Kano M; Nakazawa M; Ichida F; Nishida N; Tabata T
Heart Vessels; 2018 Jul; 33(7):802-819. PubMed ID: 29349559
[TBL] [Abstract][Full Text] [Related]
14. In Vitro Analyses of Novel HCN4 Gene Mutations.
Möller M; Silbernagel N; Wrobel E; Stallmayer B; Amedonu E; Rinné S; Peischard S; Meuth SG; Wünsch B; Strutz-Seebohm N; Decher N; Schulze-Bahr E; Seebohm G
Cell Physiol Biochem; 2018; 49(3):1197-1207. PubMed ID: 30196304
[TBL] [Abstract][Full Text] [Related]
15. Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4.
Baruscotti M; Bucchi A; Viscomi C; Mandelli G; Consalez G; Gnecchi-Rusconi T; Montano N; Casali KR; Micheloni S; Barbuti A; DiFrancesco D
Proc Natl Acad Sci U S A; 2011 Jan; 108(4):1705-10. PubMed ID: 21220308
[TBL] [Abstract][Full Text] [Related]
16. The symptom complex of familial sinus node dysfunction and myocardial noncompaction is associated with mutations in the HCN4 channel.
Schweizer PA; Schröter J; Greiner S; Haas J; Yampolsky P; Mereles D; Buss SJ; Seyler C; Bruehl C; Draguhn A; Koenen M; Meder B; Katus HA; Thomas D
J Am Coll Cardiol; 2014 Aug; 64(8):757-67. PubMed ID: 25145518
[TBL] [Abstract][Full Text] [Related]
17. HCN4 pacemaker channels attenuate the parasympathetic response and stabilize the spontaneous firing of the sinoatrial node.
Kozasa Y; Nakashima N; Ito M; Ishikawa T; Kimoto H; Ushijima K; Makita N; Takano M
J Physiol; 2018 Mar; 596(5):809-825. PubMed ID: 29315578
[TBL] [Abstract][Full Text] [Related]
18. Free energy landscape remodeling of the cardiac pacemaker channel explains the molecular basis of familial sinus bradycardia.
Boulton S; Akimoto M; Akbarizadeh S; Melacini G
J Biol Chem; 2017 Apr; 292(15):6414-6428. PubMed ID: 28174302
[TBL] [Abstract][Full Text] [Related]
19. A gain-of-function HCN4 mutant in the HCN domain is responsible for inappropriate sinus tachycardia in a Spanish family.
Cámara-Checa A; Perin F; Rubio-Alarcón M; Dago M; Crespo-García T; Rapún J; Marín M; Cebrián J; Gómez R; Bermúdez-Jiménez F; Monserrat L; Tamargo J; Caballero R; Jiménez-Jáimez J; Delpón E
Proc Natl Acad Sci U S A; 2023 Dec; 120(49):e2305135120. PubMed ID: 38032931
[TBL] [Abstract][Full Text] [Related]
20. Sick sinus syndrome in HCN1-deficient mice.
Fenske S; Krause SC; Hassan SI; Becirovic E; Auer F; Bernard R; Kupatt C; Lange P; Ziegler T; Wotjak CT; Zhang H; Hammelmann V; Paparizos C; Biel M; Wahl-Schott CA
Circulation; 2013 Dec; 128(24):2585-94. PubMed ID: 24218458
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
