BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 28826912)

  • 1. Edaravone is a candidate agent for spinal muscular atrophy: In vitro analysis using a human induced pluripotent stem cells-derived disease model.
    Ando S; Funato M; Ohuchi K; Kameyama T; Inagaki S; Seki J; Kawase C; Tsuruma K; Shimazawa M; Kaneko H; Hara H
    Eur J Pharmacol; 2017 Nov; 814():161-168. PubMed ID: 28826912
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Established Stem Cell Model of Spinal Muscular Atrophy Is Applicable in the Evaluation of the Efficacy of Thyrotropin-Releasing Hormone Analog.
    Ohuchi K; Funato M; Kato Z; Seki J; Kawase C; Tamai Y; Ono Y; Nagahara Y; Noda Y; Kameyama T; Ando S; Tsuruma K; Shimazawa M; Hara H; Kaneko H
    Stem Cells Transl Med; 2016 Feb; 5(2):152-63. PubMed ID: 26683872
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Protective Effects of Levetiracetam on a Human iPSCs-Derived Spinal Muscular Atrophy Model.
    Ando S; Funato M; Ohuchi K; Inagaki S; Sato A; Seki J; Kawase C; Saito T; Nishio H; Nakamura S; Shimazawa M; Kaneko H; Hara H
    Neurochem Res; 2019 Jul; 44(7):1773-1779. PubMed ID: 31102025
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Abnormal mitochondrial transport and morphology as early pathological changes in human models of spinal muscular atrophy.
    Xu CC; Denton KR; Wang ZB; Zhang X; Li XJ
    Dis Model Mech; 2016 Jan; 9(1):39-49. PubMed ID: 26586529
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modeling the differential phenotypes of spinal muscular atrophy with high-yield generation of motor neurons from human induced pluripotent stem cells.
    Lin X; Li JJ; Qian WJ; Zhang QJ; Wang ZF; Lu YQ; Dong EL; He J; Wang N; Ma LX; Chen WJ
    Oncotarget; 2017 Jun; 8(26):42030-42042. PubMed ID: 28159932
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SMN deficiency does not induce oxidative stress in SMA iPSC-derived astrocytes or motor neurons.
    Patitucci TN; Ebert AD
    Hum Mol Genet; 2016 Feb; 25(3):514-23. PubMed ID: 26643950
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loganin possesses neuroprotective properties, restores SMN protein and activates protein synthesis positive regulator Akt/mTOR in experimental models of spinal muscular atrophy.
    Tseng YT; Chen CS; Jong YJ; Chang FR; Lo YC
    Pharmacol Res; 2016 Sep; 111():58-75. PubMed ID: 27241020
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Calpain system is altered in survival motor neuron-reduced cells from in vitro and in vivo spinal muscular atrophy models.
    de la Fuente S; Sansa A; Hidalgo I; Vivancos N; Romero-Guevara R; Garcera A; Soler RM
    Cell Death Dis; 2020 Jun; 11(6):487. PubMed ID: 32587237
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Triptolide increases transcript and protein levels of survival motor neurons in human SMA fibroblasts and improves survival in SMA-like mice.
    Hsu YY; Jong YJ; Tsai HH; Tseng YT; An LM; Lo YC
    Br J Pharmacol; 2012 Jun; 166(3):1114-26. PubMed ID: 22220673
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy.
    Hor JH; Soh ES; Tan LY; Lim VJW; Santosa MM; Winanto ; Ho BX; Fan Y; Soh BS; Ng SY
    Cell Death Dis; 2018 Oct; 9(11):1100. PubMed ID: 30368521
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recapitulation of spinal motor neuron-specific disease phenotypes in a human cell model of spinal muscular atrophy.
    Wang ZB; Zhang X; Li XJ
    Cell Res; 2013 Mar; 23(3):378-93. PubMed ID: 23208423
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Survival motor neuron protein regulates oxidative stress and inflammatory response in microglia of the spinal cord in spinal muscular atrophy.
    Ando S; Osanai D; Takahashi K; Nakamura S; Shimazawa M; Hara H
    J Pharmacol Sci; 2020 Dec; 144(4):204-211. PubMed ID: 33070839
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy.
    Sison SL; Patitucci TN; Seminary ER; Villalon E; Lorson CL; Ebert AD
    Hum Mol Genet; 2017 Sep; 26(17):3409-3420. PubMed ID: 28637335
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased levels of UCHL1 are a compensatory response to disrupted ubiquitin homeostasis in spinal muscular atrophy and do not represent a viable therapeutic target.
    Powis RA; Mutsaers CA; Wishart TM; Hunter G; Wirth B; Gillingwater TH
    Neuropathol Appl Neurobiol; 2014 Dec; 40(7):873-87. PubMed ID: 25041530
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genome-wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy.
    Ng SY; Soh BS; Rodriguez-Muela N; Hendrickson DG; Price F; Rinn JL; Rubin LL
    Cell Stem Cell; 2015 Nov; 17(5):569-84. PubMed ID: 26321202
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial defects in the respiratory complex I contribute to impaired translational initiation via ROS and energy homeostasis in SMA motor neurons.
    Thelen MP; Wirth B; Kye MJ
    Acta Neuropathol Commun; 2020 Dec; 8(1):223. PubMed ID: 33353564
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs.
    Yoshida M; Kitaoka S; Egawa N; Yamane M; Ikeda R; Tsukita K; Amano N; Watanabe A; Morimoto M; Takahashi J; Hosoi H; Nakahata T; Inoue H; Saito MK
    Stem Cell Reports; 2015 Apr; 4(4):561-8. PubMed ID: 25801509
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Spinal muscular atrophy phenotype is ameliorated in human motor neurons by SMN increase via different novel RNA therapeutic approaches.
    Nizzardo M; Simone C; Dametti S; Salani S; Ulzi G; Pagliarani S; Rizzo F; Frattini E; Pagani F; Bresolin N; Comi G; Corti S
    Sci Rep; 2015 Jun; 5():11746. PubMed ID: 26123042
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Investigation of New Morpholino Oligomers to Increase Survival Motor Neuron Protein Levels in Spinal Muscular Atrophy.
    Ramirez A; Crisafulli SG; Rizzuti M; Bresolin N; Comi GP; Corti S; Nizzardo M
    Int J Mol Sci; 2018 Jan; 19(1):. PubMed ID: 29316633
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Perturbed MicroRNA Expression Pattern Characterizes Embryonic Neural Stem Cells Derived from a Severe Mouse Model of Spinal Muscular Atrophy (SMA).
    Luchetti A; Ciafrè SA; Murdocca M; Malgieri A; Masotti A; Sanchez M; Farace MG; Novelli G; Sangiuolo F
    Int J Mol Sci; 2015 Aug; 16(8):18312-27. PubMed ID: 26258776
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.