281 related articles for article (PubMed ID: 28827365)
21. Leukotriene A4 hydrolase, a bifunctional enzyme. Distinction of leukotriene A4 hydrolase and aminopeptidase activities by site-directed mutagenesis at Glu-297.
Minami M; Bito H; Ohishi N; Tsuge H; Miyano M; Mori M; Wada H; Mutoh H; Shimada S; Izumi T
FEBS Lett; 1992 Sep; 309(3):353-7. PubMed ID: 1516710
[TBL] [Abstract][Full Text] [Related]
22. Development of a homogeneous time-resolved fluorescence leukotriene B4 assay for determining the activity of leukotriene A4 hydrolase.
Liang AM; Claret E; Ouled-Diaf J; Jean A; Vogel D; Light DR; Jones SW; Guilford WJ; Parkinson JF; Snider RM
J Biomol Screen; 2007 Jun; 12(4):536-45. PubMed ID: 17384330
[TBL] [Abstract][Full Text] [Related]
23. Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates.
Rudberg PC; Tholander F; Andberg M; Thunnissen MM; Haeggström JZ
J Biol Chem; 2004 Jun; 279(26):27376-82. PubMed ID: 15078870
[TBL] [Abstract][Full Text] [Related]
24. Crystal structure of the cold-active aminopeptidase from Colwellia psychrerythraea, a close structural homologue of the human bifunctional leukotriene A4 hydrolase.
Bauvois C; Jacquamet L; Huston AL; Borel F; Feller G; Ferrer JL
J Biol Chem; 2008 Aug; 283(34):23315-25. PubMed ID: 18539590
[TBL] [Abstract][Full Text] [Related]
25. Coupling of recombinant 5-lipoxygenase and leukotriene A4 hydrolase activities and transcellular metabolism of leukotriene A4 in Sf9 insect cells.
Mancini JA; Evans JF
Eur J Biochem; 1993 Dec; 218(2):477-84. PubMed ID: 8269937
[TBL] [Abstract][Full Text] [Related]
26. Hybrid Receptor-Bound/MM-GBSA-Per-residue Energy-Based Pharmacophore Modelling: Enhanced Approach for Identification of Selective LTA4H Inhibitors as Potential Anti-inflammatory Drugs.
Appiah-Kubi P; Soliman M
Cell Biochem Biophys; 2017 Mar; 75(1):35-48. PubMed ID: 27914004
[TBL] [Abstract][Full Text] [Related]
27. Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation.
Thunnissen MM; Nordlund P; Haeggström JZ
Nat Struct Biol; 2001 Feb; 8(2):131-5. PubMed ID: 11175901
[TBL] [Abstract][Full Text] [Related]
28. In silico modeling of the molecular structure and binding of leukotriene A4 into leukotriene A4 hydrolase.
Paz PB; Vega-Hissi EG; Estrada MR; Garro Martinez JC
Chem Biol Drug Des; 2012 Dec; 80(6):902-8. PubMed ID: 22913921
[TBL] [Abstract][Full Text] [Related]
29. Theoretical Characterization of the Step-by-Step Mechanism of Conversion of Leukotriene A
Canyelles-Niño M; González-Lafont À; Lluch JM
Int J Mol Sci; 2022 Mar; 23(6):. PubMed ID: 35328561
[TBL] [Abstract][Full Text] [Related]
30. Determination of the contribution of cysteinyl leukotrienes and leukotriene B4 in acute inflammatory responses using 5-lipoxygenase- and leukotriene A4 hydrolase-deficient mice.
Byrum RS; Goulet JL; Snouwaert JN; Griffiths RJ; Koller BH
J Immunol; 1999 Dec; 163(12):6810-9. PubMed ID: 10586081
[TBL] [Abstract][Full Text] [Related]
31. Site-directed mutagenesis of leukotriene A4 hydrolase: distinction of leukotriene A4 hydrolase and aminopeptidase activities.
Izumi T; Minami M; Ohishi N; Bito H; Shimizu T
J Lipid Mediat; 1993; 6(1-3):53-8. PubMed ID: 8358013
[TBL] [Abstract][Full Text] [Related]
32. Leukotriene A4 hydrolase: structural and functional properties of the active center.
Haeggström JZ; Wetterholm A; Medina JF; Samuelsson B
J Lipid Mediat; 1993; 6(1-3):1-13. PubMed ID: 8357975
[TBL] [Abstract][Full Text] [Related]
33. Molecular cloning and functional expression of a Caenorhabditis elegans aminopeptidase structurally related to mammalian leukotriene A4 hydrolases.
Baset HA; Ford-Hutchinson AW; O'Neill GP
J Biol Chem; 1998 Oct; 273(43):27978-87. PubMed ID: 9774412
[TBL] [Abstract][Full Text] [Related]
34. Inhibitors of leukotriene A4 (LTA4) hydrolase as potential anti-inflammatory agents.
Penning TD
Curr Pharm Des; 2001 Feb; 7(3):163-79. PubMed ID: 11311111
[TBL] [Abstract][Full Text] [Related]
35. Leukotriene A4 hydrolase as a target for cancer prevention and therapy.
Chen X; Wang S; Wu N; Yang CS
Curr Cancer Drug Targets; 2004 May; 4(3):267-83. PubMed ID: 15134534
[TBL] [Abstract][Full Text] [Related]
36. Potent and selective inhibitors of leukotriene A4 hydrolase: effects on purified enzyme and human polymorphonuclear leukocytes.
Wetterholm A; Haeggström JZ; Samuelsson B; Yuan W; Munoz B; Wong CH
J Pharmacol Exp Ther; 1995 Oct; 275(1):31-7. PubMed ID: 7562564
[TBL] [Abstract][Full Text] [Related]
37. Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking.
Audat SA; Al-Shar'i NA; Al-Oudat BA; Bryant-Friedrich A; Bedi MF; Zayed AL; Al-Balas QA
Molecules; 2020 Jun; 25(12):. PubMed ID: 32580506
[TBL] [Abstract][Full Text] [Related]
38. Leukotriene A4 hydrolase/aminopeptidase. Glutamate 271 is a catalytic residue with specific roles in two distinct enzyme mechanisms.
Rudberg PC; Tholander F; Thunnissen MM; Haeggström JZ
J Biol Chem; 2002 Jan; 277(2):1398-404. PubMed ID: 11675384
[TBL] [Abstract][Full Text] [Related]
39. Leukotriene A5 is a substrate and an inhibitor of rat and human neutrophil LTA4 hydrolase.
Nathaniel DJ; Evans JF; Leblanc Y; Léveillé C; Fitzsimmons BJ; Ford-Hutchinson AW
Biochem Biophys Res Commun; 1985 Sep; 131(2):827-35. PubMed ID: 2996528
[TBL] [Abstract][Full Text] [Related]
40. Leukotriene A4 hydrolase: determination of the three zinc-binding ligands by site-directed mutagenesis and zinc analysis.
Medina JF; Wetterholm A; Rådmark O; Shapiro R; Haeggström JZ; Vallee BL; Samuelsson B
Proc Natl Acad Sci U S A; 1991 Sep; 88(17):7620-4. PubMed ID: 1881903
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]