These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 28835803)

  • 1. Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group.
    Lassalas P; Oukoloff K; Makani V; James M; Tran V; Yao Y; Huang L; Vijayendran K; Monti L; Trojanowski JQ; Lee VM; Kozlowski MC; Smith AB; Brunden KR; Ballatore C
    ACS Med Chem Lett; 2017 Aug; 8(8):864-868. PubMed ID: 28835803
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure property relationships of N-acylsulfonamides and related bioisosteres.
    Francisco KR; Varricchio C; Paniak TJ; Kozlowski MC; Brancale A; Ballatore C
    Eur J Med Chem; 2021 Jun; 218():113399. PubMed ID: 33823393
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure Property Relationships of Carboxylic Acid Isosteres.
    Lassalas P; Gay B; Lasfargeas C; James MJ; Tran V; Vijayendran KG; Brunden KR; Kozlowski MC; Thomas CJ; Smith AB; Huryn DM; Ballatore C
    J Med Chem; 2016 Apr; 59(7):3183-203. PubMed ID: 26967507
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The application of bioisosteres in drug design for novel drug discovery: focusing on acid protease inhibitors.
    Hamada Y; Kiso Y
    Expert Opin Drug Discov; 2012 Oct; 7(10):903-22. PubMed ID: 22873630
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and functionalization of cyclic sulfonimidamides: a novel chiral heterocyclic carboxylic Acid bioisostere.
    Pemberton N; Graden H; Evertsson E; Bratt E; Lepistö M; Johannesson P; Svensson PH
    ACS Med Chem Lett; 2012 Jul; 3(7):574-8. PubMed ID: 24900513
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of druglike parameters via in silico techniques for a series of heterocyclic monosquarate-amide derivatives as potential carboxylic acid bioisosteres.
    Long N; Le Gresley A; Wozniak A; Brough S; Wren SP
    Bioorg Med Chem; 2024 Jan; 98():117565. PubMed ID: 38142561
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological activity of 2-[6-methyl-4-(thietan-3-yloxy)pyrimidin-2-ylthio]acetohydrazide derivatives.
    Meshcheryakova S; Shumadalova A; Beylerli O; Gareev I
    ADMET DMPK; 2021; 9(2):167-176. PubMed ID: 35299769
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Strain-Release-Driven Modular Synthesis of Oxetane-Based Amide Bioisosteres: Concise, Robust and Scalable Approach.
    Spránitz P; Sőregi P; Hegedüs K; Igriczi B; Szakács G; Jemnitz K; Szabó P; Galushchak Y; Mykhailiuk PK; Soós T
    Angew Chem Int Ed Engl; 2024 Jul; ():e202410554. PubMed ID: 38989571
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-property relationships of fluorinated carboxylic acid bioisosteres.
    Alle T; Joyasawal S; Oukoloff K; Long K; Owyang Z; Francisco KR; Cahard D; Huryn DM; Ballatore C
    Bioorg Med Chem Lett; 2023 Jul; 91():129363. PubMed ID: 37295616
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reactions of oxetan-3-tert-butylsulfinimine for the preparation of substituted 3-aminooxetanes.
    Hamzik PJ; Brubaker JD
    Org Lett; 2010 Mar; 12(5):1116-9. PubMed ID: 20141162
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recent Developments in the Practical Application of Novel Carboxylic Acid Bioisosteres.
    Horgan C; O'Sullivan TP
    Curr Med Chem; 2022; 29(13):2203-2234. PubMed ID: 34420501
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New substrates and inhibitors of gamma-aminobutyric acid aminotransferase containing bioisosteres of the carboxylic acid group: design, synthesis, and biological activity.
    Yuan H; Silverman RB
    Bioorg Med Chem; 2006 Mar; 14(5):1331-8. PubMed ID: 16263300
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluation of a diverse set of potential P1 carboxylic acid bioisosteres in hepatitis C virus NS3 protease inhibitors.
    Rönn R; Gossas T; Sabnis YA; Daoud H; Kerblom E; Danielson UH; Sandström A
    Bioorg Med Chem; 2007 Jun; 15(12):4057-68. PubMed ID: 17449253
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and biological evaluation of some novel indolizine derivatives as dual cyclooxygenase and lipoxygenase inhibitor for anti-inflammatory activity.
    Shrivastava SK; Srivastava P; Bandresh R; Tripathi PN; Tripathi A
    Bioorg Med Chem; 2017 Aug; 25(16):4424-4432. PubMed ID: 28669741
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bioisoteres for carboxylic acids: From ionized isosteres to novel unionized replacements.
    Hall A; Chatzopoulou M; Frost J
    Bioorg Med Chem; 2024 Apr; 104():117653. PubMed ID: 38579492
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The chemistry of azetidin-3-ones, oxetan-3-ones, and thietan-3-ones.
    Dejaegher Y; Kuz'menok NM; Zvonok AM; De Kimpe N
    Chem Rev; 2002 Jan; 102(1):29-60. PubMed ID: 11782128
    [No Abstract]   [Full Text] [Related]  

  • 17. Nonsteroidal antiinflammatory agents, XVIII: C-5 functionalized 6,7-diphenyl-2,3-dihydro-1H-pyrrolizines as inhibitors of bovine cyclooxygenase and 5-lipoxygenase.
    Dannhardt G; Kiefer W
    Arch Pharm (Weinheim); 1994 Aug; 327(8):509-14. PubMed ID: 7944906
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Further optimization of sulfonamide analogs as EP1 receptor antagonists: synthesis and evaluation of bioisosteres for the carboxylic acid group.
    Naganawa A; Matsui T; Ima M; Saito T; Murota M; Aratani Y; Kijima H; Yamamoto H; Maruyama T; Ohuchida S; Nakai H; Toda M
    Bioorg Med Chem; 2006 Nov; 14(21):7121-37. PubMed ID: 16879970
    [TBL] [Abstract][Full Text] [Related]  

  • 19. LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates.
    Zur AA; Chien HC; Augustyn E; Flint A; Heeren N; Finke K; Hernandez C; Hansen L; Miller S; Lin L; Giacomini KM; Colas C; Schlessinger A; Thomas AA
    Bioorg Med Chem Lett; 2016 Oct; 26(20):5000-5006. PubMed ID: 27624080
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibitory effects of 2-substituted-1-naphthol derivatives on cyclooxygenase I and II.
    Kongkathip B; Sangma C; Kirtikara K; Luangkamin S; Hasitapan K; Jongkon N; Hannongbua S; Kongkathip N
    Bioorg Med Chem; 2005 Mar; 13(6):2167-75. PubMed ID: 15727869
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.