128 related articles for article (PubMed ID: 28837200)
1. Carboxylate isosteres for caspase inhibitors: the acylsulfonamide case revisited.
Adriaenssens Y; Jiménez Fernández D; Vande Walle L; Elvas F; Joossens J; Lambeir A; Augustyns K; Lamkanfi M; Van der Veken P
Org Biomol Chem; 2017 Sep; 15(35):7456-7473. PubMed ID: 28837200
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and evaluation of potent and selective beta(3) adrenergic receptor agonists containing acylsulfonamide, sulfonylsulfonamide, and sulfonylurea carboxylic acid isosteres.
Uehling DE; Donaldson KH; Deaton DN; Hyman CE; Sugg EE; Barrett DG; Hughes RG; Reitter B; Adkison KK; Lancaster ME; Lee F; Hart R; Paulik MA; Sherman BW; True T; Cowan C
J Med Chem; 2002 Jan; 45(3):567-83. PubMed ID: 11806709
[TBL] [Abstract][Full Text] [Related]
3. N-acylsulfonamides: Synthetic routes and biological potential in medicinal chemistry.
Ammazzalorso A; De Filippis B; Giampietro L; Amoroso R
Chem Biol Drug Des; 2017 Dec; 90(6):1094-1105. PubMed ID: 28632928
[TBL] [Abstract][Full Text] [Related]
4. Evaluation of the cyclopentane-1,2-dione as a potential bio-isostere of the carboxylic acid functional group.
Ballatore C; Gay B; Huang L; Robinson KH; James MJ; Trojanowski JQ; Lee VM; Brunden KR; Smith AB
Bioorg Med Chem Lett; 2014 Sep; 24(17):4171-5. PubMed ID: 25127105
[TBL] [Abstract][Full Text] [Related]
5. Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors.
Firoozpour L; Gao L; Moghimi S; Pasalar P; Davoodi J; Wang MW; Rezaei Z; Dadgar A; Yahyavi H; Amanlou M; Foroumadi A
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1674-1684. PubMed ID: 32842789
[TBL] [Abstract][Full Text] [Related]
6. Variation of the aryl substituent on the piperazine ring within the 4-(piperazin-1-yl)-2,6-di(pyrrolidin-1-yl)pyrimidine scaffold unveils potent, non-competitive inhibitors of the inflammatory caspases.
Kent CR; Bryja M; Gustafson HA; Kawarski MY; Lenti G; Pierce EN; Knopp RC; Ceja V; Pati B; Walters DE; Karver CE
Bioorg Med Chem Lett; 2016 Nov; 26(22):5476-5480. PubMed ID: 27777011
[TBL] [Abstract][Full Text] [Related]
7. Influence of 4- or 5-substituents on the pyrrolidine ring of 5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin derivatives on their inhibitory activities towards caspases-3 and -7.
Limpachayaporn P; Riemann B; Kopka K; Schober O; Schäfers M; Haufe G
Eur J Med Chem; 2013 Jun; 64():562-78. PubMed ID: 23685941
[TBL] [Abstract][Full Text] [Related]
8. Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor.
Winters MP; Crysler C; Subasinghe N; Ryan D; Leong L; Zhao S; Donatelli R; Yurkow E; Mazzulla M; Boczon L; Manthey CL; Molloy C; Raymond H; Murray L; McAlonan L; Tomczuk B
Bioorg Med Chem Lett; 2008 Mar; 18(6):1926-30. PubMed ID: 18308567
[TBL] [Abstract][Full Text] [Related]
9. Selective detection and inhibition of active caspase-3 in cells with optimized peptides.
Vickers CJ; González-Páez GE; Wolan DW
J Am Chem Soc; 2013 Aug; 135(34):12869-76. PubMed ID: 23915420
[TBL] [Abstract][Full Text] [Related]
10. Synthesis of new fluorinated, 2-substituted 5-pyrrolidinylsulfonyl isatin derivatives as caspase-3 and caspase-7 inhibitors: nonradioactive counterparts of putative PET-compatible apoptosis imaging agents.
Limpachayaporn P; Schäfers M; Schober O; Kopka K; Haufe G
Bioorg Med Chem; 2013 Apr; 21(7):2025-36. PubMed ID: 23411396
[TBL] [Abstract][Full Text] [Related]
11. Two novel classes of fused azaisocytosine-containing congeners as promising drug candidates: Design, synthesis as well as in vitro, ex vivo and in silico studies.
Sztanke M; Rzymowska J; Janicka M; Sztanke K
Bioorg Chem; 2020 Jan; 95():103480. PubMed ID: 31864156
[TBL] [Abstract][Full Text] [Related]
12. Efficient and regiospecific syntheses of peptides with piperazic and dehydropiperazic acids via a multicomponent reaction.
Handy EL; Totaro KA; Lin CP; Sello JK
Org Lett; 2014 Jul; 16(13):3488-91. PubMed ID: 24937740
[TBL] [Abstract][Full Text] [Related]
13. Nonbenzamidine acylsulfonamide tissue factor-factor VIIa inhibitors.
Glunz PW; Zhang X; Zou Y; Delucca I; Nirschl AH; Cheng X; Weigelt CA; Cheney DL; Wei A; Anumula R; Luettgen JM; Rendina AR; Harpel M; Luo G; Knabb R; Wong PC; Wexler RR; Priestley ES
Bioorg Med Chem Lett; 2013 Sep; 23(18):5244-8. PubMed ID: 23845220
[TBL] [Abstract][Full Text] [Related]
14. A novel class of small-molecule caspase-3 inhibitors prepared by multicomponent reactions.
Zhu Q; Gao L; Chen Z; Zheng S; Shu H; Li J; Jiang H; Liu S
Eur J Med Chem; 2012 Aug; 54():232-8. PubMed ID: 22652225
[TBL] [Abstract][Full Text] [Related]
15. Carboxylic acid isosteres improve the activity of ring-fused 2-pyridones that inhibit pilus biogenesis in E. coli.
Berg V; Das P; Chorell E; Hedenström M; Pinkner JS; Hultgren SJ; Almqvist F
Bioorg Med Chem Lett; 2008 Jun; 18(12):3536-40. PubMed ID: 18499455
[TBL] [Abstract][Full Text] [Related]
16. Fused Bicyclic Caspase-1 Inhibitors Assembled by Copper-Free Strain-Promoted Alkyne-Azide Cycloaddition (SPAAC).
Qian L; Zhang CJ; Wu J; Yao SQ
Chemistry; 2017 Jan; 23(2):360-369. PubMed ID: 27882694
[TBL] [Abstract][Full Text] [Related]
17. N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies.
Chu W; Zhang J; Zeng C; Rothfuss J; Tu Z; Chu Y; Reichert DE; Welch MJ; Mach RH
J Med Chem; 2005 Dec; 48(24):7637-47. PubMed ID: 16302804
[TBL] [Abstract][Full Text] [Related]
18. Structure-based design, synthesis and evaluation of 2,4-diaminopyrimidine derivatives as novel caspase-1 inhibitors.
Patel S; Modi P; Ranjan V; Chhabria M
Bioorg Chem; 2018 Aug; 78():258-268. PubMed ID: 29614437
[TBL] [Abstract][Full Text] [Related]
19. 1,2,4-Triazolsulfone: A novel isosteric replacement of acylsulfonamides in the context of Na
Boezio AA; Andrews K; Boezio C; Chu-Moyer M; Copeland KW; DiMauro EF; Foti RS; Fremeau RT; Gao H; Geuns-Meyer S; Graceffa RF; Gunaydin H; Huang H; La DS; Ligutti J; Moyer BD; Peterson EA; Yu V; Weiss MM
Bioorg Med Chem Lett; 2018 Jun; 28(11):2103-2108. PubMed ID: 29709252
[TBL] [Abstract][Full Text] [Related]
20. Matrix metalloproteinase-12 inhibitors: synthesis, structure-activity relationships and intestinal absorption of novel sugar-based biphenylsulfonamide carboxylates.
Cuffaro D; Camodeca C; D'Andrea F; Piragine E; Testai L; Calderone V; Orlandini E; Nuti E; Rossello A
Bioorg Med Chem; 2018 Dec; 26(22):5804-5815. PubMed ID: 30429099
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]