BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 28837958)

  • 1. Terminating the criminal collaboration in pancreatic cancer: Nanoparticle-based synergistic therapy for overcoming fibroblast-induced drug resistance.
    Wang L; Liu X; Zhou Q; Sui M; Lu Z; Zhou Z; Tang J; Miao Y; Zheng M; Wang W; Shen Y
    Biomaterials; 2017 Nov; 144():105-118. PubMed ID: 28837958
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Co-targeting of CXCR4 and hedgehog pathways disrupts tumor-stromal crosstalk and improves chemotherapeutic efficacy in pancreatic cancer.
    Khan MA; Srivastava SK; Zubair H; Patel GK; Arora S; Khushman M; Carter JE; Gorman GS; Singh S; Singh AP
    J Biol Chem; 2020 Jun; 295(25):8413-8424. PubMed ID: 32358063
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Codelivery of small molecule hedgehog inhibitor and miRNA for treating pancreatic cancer.
    Kumar V; Mondal G; Slavik P; Rachagani S; Batra SK; Mahato RI
    Mol Pharm; 2015 Apr; 12(4):1289-98. PubMed ID: 25679326
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GDC-0449 improves the antitumor activity of nano-doxorubicin in pancreatic cancer in a fibroblast-enriched microenvironment.
    Zhou Q; Zhou Y; Liu X; Shen Y
    Sci Rep; 2017 Oct; 7(1):13379. PubMed ID: 29042665
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Micelle Mixtures for Coadministration of Gemcitabine and GDC-0449 To Treat Pancreatic Cancer.
    Karaca M; Dutta R; Ozsoy Y; Mahato RI
    Mol Pharm; 2016 Jun; 13(6):1822-32. PubMed ID: 26981724
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer.
    Kumar V; Chaudhary AK; Dong Y; Zhong HA; Mondal G; Lin F; Kumar V; Mahato RI
    Sci Rep; 2017 May; 7(1):1665. PubMed ID: 28490735
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sonic-hedgehog pathway inhibition normalizes desmoplastic tumor microenvironment to improve chemo- and nanotherapy.
    Mpekris F; Papageorgis P; Polydorou C; Voutouri C; Kalli M; Pirentis AP; Stylianopoulos T
    J Control Release; 2017 Sep; 261():105-112. PubMed ID: 28662901
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prodrug polymeric micelles integrating cancer-associated fibroblasts deactivation and synergistic chemotherapy for gastric cancer.
    Zheng S; Wang J; Ding N; Chen W; Chen H; Xue M; Chen F; Ni J; Wang Z; Lin Z; Jiang H; Liu X; Wang L
    J Nanobiotechnology; 2021 Nov; 19(1):381. PubMed ID: 34802453
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hedgehog signaling antagonist GDC-0449 (Vismodegib) inhibits pancreatic cancer stem cell characteristics: molecular mechanisms.
    Singh BN; Fu J; Srivastava RK; Shankar S
    PLoS One; 2011; 6(11):e27306. PubMed ID: 22087285
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacokinetic-pharmacodynamic analysis of vismodegib in preclinical models of mutational and ligand-dependent Hedgehog pathway activation.
    Wong H; Alicke B; West KA; Pacheco P; La H; Januario T; Yauch RL; de Sauvage FJ; Gould SE
    Clin Cancer Res; 2011 Jul; 17(14):4682-92. PubMed ID: 21610148
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer.
    Yamamoto K; Tateishi K; Kudo Y; Hoshikawa M; Tanaka M; Nakatsuka T; Fujiwara H; Miyabayashi K; Takahashi R; Tanaka Y; Ijichi H; Nakai Y; Isayama H; Morishita Y; Aoki T; Sakamoto Y; Hasegawa K; Kokudo N; Fukayama M; Koike K
    Oncotarget; 2016 Sep; 7(38):61469-61484. PubMed ID: 27528027
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel delivery of SN38 markedly inhibits tumor growth in xenografts, including a camptothecin-11-refractory model.
    Sapra P; Zhao H; Mehlig M; Malaby J; Kraft P; Longley C; Greenberger LM; Horak ID
    Clin Cancer Res; 2008 Mar; 14(6):1888-96. PubMed ID: 18347192
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel SN38 conjugate-forming nanoparticles as anticancer prodrug: in vitro and in vivo studies.
    Zhang H; Wang J; Mao W; Huang J; Wu X; Shen Y; Sui M
    J Control Release; 2013 Mar; 166(2):147-58. PubMed ID: 23266448
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel lipophilic SN38 prodrug forming stable liposomes for colorectal carcinoma therapy.
    Xing J; Zhang X; Wang Z; Zhang H; Chen P; Zhou G; Sun C; Gu N; Ji M
    Int J Nanomedicine; 2019; 14():5201-5213. PubMed ID: 31371956
    [No Abstract]   [Full Text] [Related]  

  • 15. Efficient elimination of pancreatic cancer stem cells by hedgehog/GLI inhibitor GANT61 in combination with mTOR inhibition.
    Miyazaki Y; Matsubara S; Ding Q; Tsukasa K; Yoshimitsu M; Kosai K; Takao S
    Mol Cancer; 2016 Jun; 15(1):49. PubMed ID: 27349387
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors.
    LoRusso PM; Rudin CM; Reddy JC; Tibes R; Weiss GJ; Borad MJ; Hann CL; Brahmer JR; Chang I; Darbonne WC; Graham RA; Zerivitz KL; Low JA; Von Hoff DD
    Clin Cancer Res; 2011 Apr; 17(8):2502-11. PubMed ID: 21300762
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sonic hedgehog paracrine signaling activates stromal cells to promote perineural invasion in pancreatic cancer.
    Li X; Wang Z; Ma Q; Xu Q; Liu H; Duan W; Lei J; Ma J; Wang X; Lv S; Han L; Li W; Guo J; Guo K; Zhang D; Wu E; Xie K
    Clin Cancer Res; 2014 Aug; 20(16):4326-38. PubMed ID: 24947933
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stroma.
    Geleta B; Park KC; Jansson PJ; Sahni S; Maleki S; Xu Z; Murakami T; Pajic M; Apte MV; Richardson DR; Kovacevic Z
    FASEB J; 2021 Feb; 35(2):e21347. PubMed ID: 33484481
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nanoparticle delivery of an SN38 conjugate is more effective than irinotecan in a mouse model of neuroblastoma.
    Iyer R; Croucher JL; Chorny M; Mangino JL; Alferiev IS; Levy RJ; Kolla V; Brodeur GM
    Cancer Lett; 2015 May; 360(2):205-12. PubMed ID: 25684664
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anthothecol-encapsulated PLGA nanoparticles inhibit pancreatic cancer stem cell growth by modulating sonic hedgehog pathway.
    Verma RK; Yu W; Singh SP; Shankar S; Srivastava RK
    Nanomedicine; 2015 Nov; 11(8):2061-70. PubMed ID: 26199979
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.