These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 28838668)

  • 1. Copper- and Zinc-Promoted Interdomain Structure in the Prion Protein: A Mechanism for Autoinhibition of the Neurotoxic N-Terminus.
    Evans EGB; Millhauser GL
    Prog Mol Biol Transl Sci; 2017; 150():35-56. PubMed ID: 28838668
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interaction between Prion Protein's Copper-Bound Octarepeat Domain and a Charged C-Terminal Pocket Suggests a Mechanism for N-Terminal Regulation.
    Evans EG; Pushie MJ; Markham KA; Lee HW; Millhauser GL
    Structure; 2016 Jul; 24(7):1057-67. PubMed ID: 27265848
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Both N-Terminal and C-Terminal Histidine Residues of the Prion Protein Are Essential for Copper Coordination and Neuroprotective Self-Regulation.
    Schilling KM; Tao L; Wu B; Kiblen JTM; Ubilla-Rodriguez NC; Pushie MJ; Britt RD; Roseman GP; Harris DA; Millhauser GL
    J Mol Biol; 2020 Jul; 432(16):4408-4425. PubMed ID: 32473880
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular Features of the Zn
    Markham KA; Roseman GP; Linsley RB; Lee HW; Millhauser GL
    Biophys J; 2019 Feb; 116(4):610-620. PubMed ID: 30678993
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Zn(II) binding causes interdomain changes in the structure and flexibility of the human prion protein.
    Gielnik M; Taube M; Zhukova L; Zhukov I; Wärmländer SKTS; Svedružić Ž; Kwiatek WM; Gräslund A; Kozak M
    Sci Rep; 2021 Nov; 11(1):21703. PubMed ID: 34737343
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Altered Domain Structure of the Prion Protein Caused by Cu
    McDonald AJ; Leon DR; Markham KA; Wu B; Heckendorf CF; Schilling K; Showalter HD; Andrews PC; McComb ME; Pushie MJ; Costello CE; Millhauser GL; Harris DA
    Structure; 2019 Jun; 27(6):907-922.e5. PubMed ID: 30956132
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amyloid β Perturbs Cu(II) Binding to the Prion Protein in a Site-Specific Manner: Insights into Its Potential Neurotoxic Mechanisms.
    Posadas Y; Parra-Ojeda L; Perez-Cruz C; Quintanar L
    Inorg Chem; 2021 Jun; 60(12):8958-8972. PubMed ID: 34043332
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prion Protein Octarepeat Domain Forms Transient β-Sheet Structures upon Residue-Specific Binding to Cu(II) and Zn(II) Ions.
    Gielnik M; Szymańska A; Dong X; Jarvet J; Svedružić ŽM; Gräslund A; Kozak M; Wärmländer SKTS
    Biochemistry; 2023 Jun; 62(11):1689-1705. PubMed ID: 37163663
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Copper induces structural changes in N-terminus of human prion protein.
    Lu B; Zhao L; Qin K
    Biochem Biophys Res Commun; 2018 May; 499(3):470-474. PubMed ID: 29580990
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural Consequences of Copper Binding to the Prion Protein.
    Salzano G; Giachin G; Legname G
    Cells; 2019 Jul; 8(8):. PubMed ID: 31349611
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Copper Binding Regulates Cellular Prion Protein Function.
    Nguyen XTA; Tran TH; Cojoc D; Legname G
    Mol Neurobiol; 2019 Sep; 56(9):6121-6133. PubMed ID: 30729399
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The N-terminus of the prion protein is a toxic effector regulated by the C-terminus.
    Wu B; McDonald AJ; Markham K; Rich CB; McHugh KP; Tatzelt J; Colby DW; Millhauser GL; Harris DA
    Elife; 2017 May; 6():. PubMed ID: 28527237
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Zinc, copper, and carnosine attenuate neurotoxicity of prion fragment PrP106-126.
    Kawahara M; Koyama H; Nagata T; Sadakane Y
    Metallomics; 2011 Jul; 3(7):726-34. PubMed ID: 21442127
    [TBL] [Abstract][Full Text] [Related]  

  • 14. β-cleavage of the human prion protein impacts Cu(II) coordination at its non-octarepeat region.
    Sánchez-López C; Quintanar L
    J Inorg Biochem; 2022 Mar; 228():111686. PubMed ID: 34929540
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Specific binding modes of Cu(I) and Ag(I) with neurotoxic domain of the human prion protein.
    Valensin D; Padula EM; Hecel A; Luczkowski M; Kozlowski H
    J Inorg Biochem; 2016 Feb; 155():26-35. PubMed ID: 26606290
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The N-terminal domain of the prion protein is required and sufficient for liquid-liquid phase separation: A crucial role of the Aβ-binding domain.
    Kamps J; Lin YH; Oliva R; Bader V; Winter R; Winklhofer KF; Tatzelt J
    J Biol Chem; 2021 Jul; 297(1):100860. PubMed ID: 34102212
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Copper coordination in the full-length, recombinant prion protein.
    Burns CS; Aronoff-Spencer E; Legname G; Prusiner SB; Antholine WE; Gerfen GJ; Peisach J; Millhauser GL
    Biochemistry; 2003 Jun; 42(22):6794-803. PubMed ID: 12779334
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Liquid-liquid phase separation of the prion protein is regulated by the octarepeat domain independently of histidines and copper.
    Kamps J; Bader V; Winklhofer KF; Tatzelt J
    J Biol Chem; 2024 Jun; 300(6):107310. PubMed ID: 38657863
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prion protein with a mutant N-terminal octarepeat region undergoes cobalamin-dependent assembly into high-molecular weight complexes.
    Daude N; Lau A; Vanni I; Kang SG; Castle AR; Wohlgemuth S; Dorosh L; Wille H; Stepanova M; Westaway D
    J Biol Chem; 2022 Apr; 298(4):101770. PubMed ID: 35271850
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An inter-domain regulatory mechanism controls toxic activities of PrP
    McDonald AJ; Wu B; Harris DA
    Prion; 2017 Nov; 11(6):388-397. PubMed ID: 28960140
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.