These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 28839461)

  • 1. Glutamic Pyruvate Transaminase GPT2 Promotes Tumorigenesis of Breast Cancer Cells by Activating Sonic Hedgehog Signaling.
    Cao Y; Lin SH; Wang Y; Chin YE; Kang L; Mi J
    Theranostics; 2017; 7(12):3021-3033. PubMed ID: 28839461
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The delta subunit of the GABA
    Li N; Xu X; Liu D; Gao J; Gao Y; Wu X; Sheng H; Li Q; Mi J
    Theranostics; 2023; 13(4):1355-1369. PubMed ID: 36923530
    [No Abstract]   [Full Text] [Related]  

  • 3. GPT2 Is Induced by Hypoxia-Inducible Factor (HIF)-2 and Promotes Glioblastoma Growth.
    Zhang B; Chen Y; Bao L; Luo W
    Cells; 2022 Aug; 11(16):. PubMed ID: 36010673
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in mitochondrial enzyme GPT2 cause metabolic dysfunction and neurological disease with developmental and progressive features.
    Ouyang Q; Nakayama T; Baytas O; Davidson SM; Yang C; Schmidt M; Lizarraga SB; Mishra S; Ei-Quessny M; Niaz S; Gul Butt M; Imran Murtaza S; Javed A; Chaudhry HR; Vaughan DJ; Hill RS; Partlow JN; Yoo SY; Lam AT; Nasir R; Al-Saffar M; Barkovich AJ; Schwede M; Nagpal S; Rajab A; DeBerardinis RJ; Housman DE; Mochida GH; Morrow EM
    Proc Natl Acad Sci U S A; 2016 Sep; 113(38):E5598-607. PubMed ID: 27601654
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct breast cancer stem/progenitor cell populations require either HIF1α or loss of PHD3 to expand under hypoxic conditions.
    Iriondo O; Rábano M; Domenici G; Carlevaris O; López-Ruiz JA; Zabalza I; Berra E; Vivanco Md
    Oncotarget; 2015 Oct; 6(31):31721-39. PubMed ID: 26372732
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intermediary metabolite precursor dimethyl-2-ketoglutarate stabilizes hypoxia-inducible factor-1α by inhibiting prolyl-4-hydroxylase PHD2.
    Hou P; Kuo CY; Cheng CT; Liou JP; Ann DK; Chen Q
    PLoS One; 2014; 9(11):e113865. PubMed ID: 25420025
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exosomal GPT2 derived from triple-negative breast cancer cells promotes metastasis by activating BTRC.
    Cui M; Peng J; Zhou Y; Wang X; Cui D
    Thorac Cancer; 2023 Jul; 14(21):2018-2025. PubMed ID: 37287397
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transketolase Regulates the Metabolic Switch to Control Breast Cancer Cell Metastasis via the α-Ketoglutarate Signaling Pathway.
    Tseng CW; Kuo WH; Chan SH; Chan HL; Chang KJ; Wang LH
    Cancer Res; 2018 Jun; 78(11):2799-2812. PubMed ID: 29599405
    [TBL] [Abstract][Full Text] [Related]  

  • 9. System analysis based on glutamine catabolic-related enzymes identifies GPT2 as a novel immunotherapy target for lung adenocarcinoma.
    Wang B; Pei J; Xu S; Liu J; Yu J
    Comput Biol Med; 2023 Oct; 165():107415. PubMed ID: 37657356
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer.
    Hao Y; Samuels Y; Li Q; Krokowski D; Guan BJ; Wang C; Jin Z; Dong B; Cao B; Feng X; Xiang M; Xu C; Fink S; Meropol NJ; Xu Y; Conlon RA; Markowitz S; Kinzler KW; Velculescu VE; Brunengraber H; Willis JE; LaFramboise T; Hatzoglou M; Zhang GF; Vogelstein B; Wang Z
    Nat Commun; 2016 Jun; 7():11971. PubMed ID: 27321283
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia.
    Di Conza G; Trusso Cafarello S; Loroch S; Mennerich D; Deschoemaeker S; Di Matteo M; Ehling M; Gevaert K; Prenen H; Zahedi RP; Sickmann A; Kietzmann T; Moretti F; Mazzone M
    Cell Rep; 2017 Feb; 18(7):1699-1712. PubMed ID: 28199842
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Loss of function mutation in glutamic pyruvate transaminase 2 (GPT2) causes developmental encephalopathy.
    Celis K; Shuldiner S; Haverfield EV; Cappell J; Yang R; Gong DW; Chung WK
    J Inherit Metab Dis; 2015 Sep; 38(5):941-8. PubMed ID: 25758935
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Abrogating GPT2 in triple-negative breast cancer inhibits tumor growth and promotes autophagy.
    Mitra D; Vega-Rubin-de-Celis S; Royla N; Bernhardt S; Wilhelm H; Tarade N; Poschet G; Buettner M; Binenbaum I; Borgoni S; Vetter M; Kantelhardt EJ; Thomssen C; Chatziioannou A; Hell R; Kempa S; Müller-Decker K; Wiemann S
    Int J Cancer; 2021 Apr; 148(8):1993-2009. PubMed ID: 33368291
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sonic hedgehog (Shh) signaling promotes tumorigenicity and stemness via activation of epithelial-to-mesenchymal transition (EMT) in bladder cancer.
    Islam SS; Mokhtari RB; Noman AS; Uddin M; Rahman MZ; Azadi MA; Zlotta A; van der Kwast T; Yeger H; Farhat WA
    Mol Carcinog; 2016 May; 55(5):537-51. PubMed ID: 25728352
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Significance of prolyl hydroxylase 2 in the interference of aryl hydrocarbon receptor and hypoxia-inducible factor-1 alpha signaling.
    Seifert A; Katschinski DM; Tonack S; Fischer B; Navarrete Santos A
    Chem Res Toxicol; 2008 Feb; 21(2):341-8. PubMed ID: 18072750
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine.
    Briggs KJ; Koivunen P; Cao S; Backus KM; Olenchock BA; Patel H; Zhang Q; Signoretti S; Gerfen GJ; Richardson AL; Witkiewicz AK; Cravatt BF; Clardy J; Kaelin WG
    Cell; 2016 Jun; 166(1):126-39. PubMed ID: 27368101
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Knockdown of prolyl-4-hydroxylase domain 2 inhibits tumor growth of human breast cancer MDA-MB-231 cells by affecting TGF-β1 processing.
    Wottawa M; Leisering P; Ahlen Mv; Schnelle M; Vogel S; Malz C; Bordoli MR; Camenisch G; Hesse A; Napp J; Alves F; Kristiansen G; Farhat K; Katschinski DM
    Int J Cancer; 2013 Jun; 132(12):2787-98. PubMed ID: 23225569
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of Ciliogenesis Promotes Hedgehog Signaling, Tumorigenesis, and Metastasis in Breast Cancer.
    Hassounah NB; Nunez M; Fordyce C; Roe D; Nagle R; Bunch T; McDermott KM
    Mol Cancer Res; 2017 Oct; 15(10):1421-1430. PubMed ID: 28611083
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitochondrial GPT2 plays a pivotal role in metabolic adaptation to the perturbation of mitochondrial glutamine metabolism.
    Kim M; Gwak J; Hwang S; Yang S; Jeong SM
    Oncogene; 2019 Jun; 38(24):4729-4738. PubMed ID: 30765862
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells.
    Smith B; Schafer XL; Ambeskovic A; Spencer CM; Land H; Munger J
    Cell Rep; 2016 Oct; 17(3):821-836. PubMed ID: 27732857
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.