BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 28842166)

  • 1. The NuRD complex-mediated p21 suppression facilitates chemoresistance in BRCA-proficient breast cancer.
    Hou MF; Luo CW; Chang TM; Hung WC; Chen TY; Tsai YL; Chai CY; Pan MR
    Exp Cell Res; 2017 Oct; 359(2):458-465. PubMed ID: 28842166
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes.
    Cai Y; Geutjes EJ; de Lint K; Roepman P; Bruurs L; Yu LR; Wang W; van Blijswijk J; Mohammad H; de Rink I; Bernards R; Baylin SB
    Oncogene; 2014 Apr; 33(17):2157-68. PubMed ID: 23708667
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to poly(ADP-ribose) polymerase (PARP) inhibitor treatment.
    Pan MR; Hsieh HJ; Dai H; Hung WC; Li K; Peng G; Lin SY
    J Biol Chem; 2012 Feb; 287(9):6764-72. PubMed ID: 22219182
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CHD4 Is a Peripheral Component of the Nucleosome Remodeling and Deacetylase Complex.
    Low JK; Webb SR; Silva AP; Saathoff H; Ryan DP; Torrado M; Brofelth M; Parker BL; Shepherd NE; Mackay JP
    J Biol Chem; 2016 Jul; 291(30):15853-66. PubMed ID: 27235397
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Defeating EpCAM(+) liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinoma.
    Nio K; Yamashita T; Okada H; Kondo M; Hayashi T; Hara Y; Nomura Y; Zeng SS; Yoshida M; Hayashi T; Sunagozaka H; Oishi N; Honda M; Kaneko S
    J Hepatol; 2015 Nov; 63(5):1164-72. PubMed ID: 26095183
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes.
    Xia L; Huang W; Bellani M; Seidman MM; Wu K; Fan D; Nie Y; Cai Y; Zhang YW; Yu LR; Li H; Zahnow CA; Xie W; Chiu Yen RW; Rassool FV; Baylin SB
    Cancer Cell; 2017 May; 31(5):653-668.e7. PubMed ID: 28486105
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The N-terminal Region of Chromodomain Helicase DNA-binding Protein 4 (CHD4) Is Essential for Activity and Contains a High Mobility Group (HMG) Box-like-domain That Can Bind Poly(ADP-ribose).
    Silva AP; Ryan DP; Galanty Y; Low JK; Vandevenne M; Jackson SP; Mackay JP
    J Biol Chem; 2016 Jan; 291(2):924-38. PubMed ID: 26565020
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA.
    Terhune SS; Moorman NJ; Cristea IM; Savaryn JP; Cuevas-Bennett C; Rout MP; Chait BT; Shenk T
    PLoS Pathog; 2010 Jun; 6(6):e1000965. PubMed ID: 20585571
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acetyltransferase p300 collaborates with chromodomain helicase DNA-binding protein 4 (CHD4) to facilitate DNA double-strand break repair.
    Qi W; Chen H; Xiao T; Wang R; Li T; Han L; Zeng X
    Mutagenesis; 2016 Mar; 31(2):193-203. PubMed ID: 26546801
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4.
    Polo SE; Kaidi A; Baskcomb L; Galanty Y; Jackson SP
    EMBO J; 2010 Sep; 29(18):3130-9. PubMed ID: 20693977
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage.
    Larsen DH; Poinsignon C; Gudjonsson T; Dinant C; Payne MR; Hari FJ; Rendtlew Danielsen JM; Menard P; Sand JC; Stucki M; Lukas C; Bartek J; Andersen JS; Lukas J
    J Cell Biol; 2010 Sep; 190(5):731-40. PubMed ID: 20805324
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CHD4 regulates platinum sensitivity through MDR1 expression in ovarian cancer: A potential role of CHD4 inhibition as a combination therapy with platinum agents.
    Oyama Y; Shigeta S; Tokunaga H; Tsuji K; Ishibashi M; Shibuya Y; Shimada M; Yasuda J; Yaegashi N
    PLoS One; 2021; 16(6):e0251079. PubMed ID: 34161330
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4.
    Guillemette S; Serra RW; Peng M; Hayes JA; Konstantinopoulos PA; Green MR; Cantor SB
    Genes Dev; 2015 Mar; 29(5):489-94. PubMed ID: 25737278
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CHD4 in the DNA-damage response and cell cycle progression: not so NuRDy now.
    O'Shaughnessy A; Hendrich B
    Biochem Soc Trans; 2013 Jun; 41(3):777-82. PubMed ID: 23697937
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MBD2 and multiple domains of CHD4 are required for transcriptional repression by Mi-2/NuRD complexes.
    Ramírez J; Dege C; Kutateladze TG; Hagman J
    Mol Cell Biol; 2012 Dec; 32(24):5078-88. PubMed ID: 23071088
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.
    Hoffmeister H; Fuchs A; Erdel F; Pinz S; Gröbner-Ferreira R; Bruckmann A; Deutzmann R; Schwartz U; Maldonado R; Huber C; Dendorfer AS; Rippe K; Längst G
    Nucleic Acids Res; 2017 Oct; 45(18):10534-10554. PubMed ID: 28977666
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair.
    Gong F; Clouaire T; Aguirrebengoa M; Legube G; Miller KM
    J Cell Biol; 2017 Jul; 216(7):1959-1974. PubMed ID: 28572115
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CHD4 as an important mediator in regulating the malignant behaviors of colorectal cancer.
    Chang CL; Huang CR; Chang SJ; Wu CC; Chen HH; Luo CW; Yip HK
    Int J Biol Sci; 2021; 17(7):1660-1670. PubMed ID: 33994851
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RNAi screens identify CHD4 as an essential gene in breast cancer growth.
    D'Alesio C; Punzi S; Cicalese A; Fornasari L; Furia L; Riva L; Carugo A; Curigliano G; Criscitiello C; Pruneri G; Pelicci PG; Faretta M; Bossi D; Lanfrancone L
    Oncotarget; 2016 Dec; 7(49):80901-80915. PubMed ID: 27779108
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.
    Marques JG; Gryder BE; Pavlovic B; Chung Y; Ngo QA; Frommelt F; Gstaiger M; Song Y; Benischke K; Laubscher D; Wachtel M; Khan J; Schäfer BW
    Elife; 2020 Aug; 9():. PubMed ID: 32744500
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.