BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 28842394)

  • 1. Transforming Growth Factor-
    Ungefroren H; Witte D; Mihara K; Rauch BH; Henklein P; Jöhren O; Bonni S; Settmacher U; Lehnert H; Hollenberg MD; Kaufmann R; Gieseler F
    Mol Pharmacol; 2017 Nov; 92(5):519-532. PubMed ID: 28842394
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Proteinase-activated receptor 2 promotes TGF-β-dependent cell motility in pancreatic cancer cells by sustaining expression of the TGF-β type I receptor ALK5.
    Zeeh F; Witte D; Gädeken T; Rauch BH; Grage-Griebenow E; Leinung N; Fromm SJ; Stölting S; Mihara K; Kaufmann R; Settmacher U; Lehnert H; Hollenberg MD; Ungefroren H
    Oncotarget; 2016 Jul; 7(27):41095-41109. PubMed ID: 27248167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Role of PAR2 in TGF-β1-Induced ERK Activation and Cell Motility.
    Ungefroren H; Witte D; Fiedler C; Gädeken T; Kaufmann R; Lehnert H; Gieseler F; Rauch BH
    Int J Mol Sci; 2017 Dec; 18(12):. PubMed ID: 29261154
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential roles of Smad2 and Smad3 in the regulation of TGF-β1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1.
    Ungefroren H; Groth S; Sebens S; Lehnert H; Gieseler F; Fändrich F
    Mol Cancer; 2011 May; 10():67. PubMed ID: 21624123
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proteinase-Activated Receptor 2 May Drive Cancer Progression by Facilitating TGF-β Signaling.
    Ungefroren H; Witte D; Rauch BH; Settmacher U; Lehnert H; Gieseler F; Kaufmann R
    Int J Mol Sci; 2017 Nov; 18(11):. PubMed ID: 29165389
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dasatinib blocks transcriptional and promigratory responses to transforming growth factor-beta in pancreatic adenocarcinoma cells through inhibition of Smad signalling: implications for in vivo mode of action.
    Bartscht T; Rosien B; Rades D; Kaufmann R; Biersack H; Lehnert H; Gieseler F; Ungefroren H
    Mol Cancer; 2015 Nov; 14():199. PubMed ID: 26588899
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TGF-β1 induces proteinase-activated receptor 2 (PAR2) expression in endometriotic stromal cells and stimulates PAR2 activation-induced secretion of IL-6.
    Saito A; Osuga Y; Yoshino O; Takamura M; Hirata T; Hirota Y; Koga K; Harada M; Takemura Y; Yano T; Taketani Y
    Hum Reprod; 2011 Jul; 26(7):1892-8. PubMed ID: 21546388
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TGF-β1/ALK5-induced monocyte migration involves PI3K and p38 pathways and is not negatively affected by diabetes mellitus.
    Olieslagers S; Pardali E; Tchaikovski V; ten Dijke P; Waltenberger J
    Cardiovasc Res; 2011 Aug; 91(3):510-8. PubMed ID: 21478266
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hexachlorobenzene modulates the crosstalk between the aryl hydrocarbon receptor and transforming growth factor-β1 signaling, enhancing human breast cancer cell migration and invasion.
    Miret N; Pontillo C; Ventura C; Carozzo A; Chiappini F; Kleiman de Pisarev D; Fernández N; Cocca C; Randi A
    Toxicology; 2016 Jul; 366-367():20-31. PubMed ID: 27519288
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II.
    Kalo E; Buganim Y; Shapira KE; Besserglick H; Goldfinger N; Weisz L; Stambolsky P; Henis YI; Rotter V
    Mol Cell Biol; 2007 Dec; 27(23):8228-42. PubMed ID: 17875924
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.
    Subramanian G; Schwarz RE; Higgins L; McEnroe G; Chakravarty S; Dugar S; Reiss M
    Cancer Res; 2004 Aug; 64(15):5200-11. PubMed ID: 15289325
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transforming growth factor-beta1 downregulates caveolin-1 expression and enhances sphingosine 1-phosphate signaling in cultured vascular endothelial cells.
    Igarashi J; Shoji K; Hashimoto T; Moriue T; Yoneda K; Takamura T; Yamashita T; Kubota Y; Kosaka H
    Am J Physiol Cell Physiol; 2009 Nov; 297(5):C1263-74. PubMed ID: 19710365
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway.
    Yoo YA; Kang MH; Kim JS; Oh SC
    Carcinogenesis; 2008 Mar; 29(3):480-90. PubMed ID: 18174246
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RAC1B Suppresses TGF-β-Dependent Chemokinesis and Growth Inhibition through an Autoregulatory Feed-Forward Loop Involving PAR2 and ALK5.
    Otterbein H; Mihara K; Hollenberg MD; Lehnert H; Witte D; Ungefroren H
    Cancers (Basel); 2019 Aug; 11(8):. PubMed ID: 31434318
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transforming growth factor-β1 up-regulates connexin43 expression in human granulosa cells.
    Chen YC; Chang HM; Cheng JC; Tsai HD; Wu CH; Leung PC
    Hum Reprod; 2015 Sep; 30(9):2190-201. PubMed ID: 26202915
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BIX02189 inhibits TGF-β1-induced lung cancer cell metastasis by directly targeting TGF-β type I receptor.
    Park SJ; Choi YS; Lee S; Lee YJ; Hong S; Han S; Kim BC
    Cancer Lett; 2016 Oct; 381(2):314-22. PubMed ID: 27543359
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization.
    Hwangbo C; Tae N; Lee S; Kim O; Park OK; Kim J; Kwon SH; Lee JH
    Oncogene; 2016 Jan; 35(3):389-401. PubMed ID: 25893292
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Autocrine transforming growth factor-beta signaling mediates Smad-independent motility in human cancer cells.
    Dumont N; Bakin AV; Arteaga CL
    J Biol Chem; 2003 Jan; 278(5):3275-85. PubMed ID: 12421823
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proteinase-activated receptor 2 (PAR2) in hepatic stellate cells - evidence for a role in hepatocellular carcinoma growth in vivo.
    Mußbach F; Ungefroren H; Günther B; Katenkamp K; Henklein P; Westermann M; Settmacher U; Lenk L; Sebens S; Müller JP; Böhmer FD; Kaufmann R
    Mol Cancer; 2016 Jul; 15(1):54. PubMed ID: 27473374
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling.
    Ungefroren H; Sebens S; Giehl K; Helm O; Groth S; Fändrich F; Röcken C; Sipos B; Lehnert H; Gieseler F
    Oncotarget; 2014 Jan; 5(1):277-90. PubMed ID: 24378395
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.