218 related articles for article (PubMed ID: 28842649)
1. Structure-based drug discovery for combating influenza virus by targeting the PA-PB1 interaction.
Watanabe K; Ishikawa T; Otaki H; Mizuta S; Hamada T; Nakagaki T; Ishibashi D; Urata S; Yasuda J; Tanaka Y; Nishida N
Sci Rep; 2017 Aug; 7(1):9500. PubMed ID: 28842649
[TBL] [Abstract][Full Text] [Related]
2. Identification of small molecule inhibitors for influenza a virus using in silico and in vitro approaches.
Makau JN; Watanabe K; Ishikawa T; Mizuta S; Hamada T; Kobayashi N; Nishida N
PLoS One; 2017; 12(3):e0173582. PubMed ID: 28273150
[TBL] [Abstract][Full Text] [Related]
3. Influenza A virus polymerase: an attractive target for next-generation anti-influenza therapeutics.
Zhou Z; Liu T; Zhang J; Zhan P; Liu X
Drug Discov Today; 2018 Mar; 23(3):503-518. PubMed ID: 29339107
[TBL] [Abstract][Full Text] [Related]
4. A Broad Anti-influenza Hybrid Small Molecule That Potently Disrupts the Interaction of Polymerase Acidic Protein-Basic Protein 1 (PA-PB1) Subunits.
Massari S; Nannetti G; Desantis J; Muratore G; Sabatini S; Manfroni G; Mercorelli B; Cecchetti V; Palù G; Cruciani G; Loregian A; Goracci L; Tabarrini O
J Med Chem; 2015 May; 58(9):3830-42. PubMed ID: 25856229
[TBL] [Abstract][Full Text] [Related]
5. Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance.
Nannetti G; Massari S; Mercorelli B; Bertagnin C; Desantis J; Palù G; Tabarrini O; Loregian A
Antiviral Res; 2019 May; 165():55-64. PubMed ID: 30885750
[TBL] [Abstract][Full Text] [Related]
6. Identification of influenza polymerase inhibitors targeting C-terminal domain of PA through surface plasmon resonance screening.
Lo CY; Li OT; Tang WP; Hu C; Wang GX; Ngo JC; Wan DC; Poon LL; Shaw PC
Sci Rep; 2018 Feb; 8(1):2280. PubMed ID: 29396435
[TBL] [Abstract][Full Text] [Related]
7. Identification of a novel small-molecule compound targeting the influenza A virus polymerase PB1-PB2 interface.
Yuan S; Chu H; Ye J; Singh K; Ye Z; Zhao H; Kao RY; Chow BK; Zhou J; Zheng BJ
Antiviral Res; 2017 Jan; 137():58-66. PubMed ID: 27840201
[TBL] [Abstract][Full Text] [Related]
8. Packaging signals in the 5'-ends of influenza virus PA, PB1, and PB2 genes as potential targets to develop nucleic-acid based antiviral molecules.
Giannecchini S; Wise HM; Digard P; Clausi V; Del Poggetto E; Vesco L; Puzelli S; Donatelli I; Azzi A
Antiviral Res; 2011 Oct; 92(1):64-72. PubMed ID: 21741410
[TBL] [Abstract][Full Text] [Related]
9. Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase.
Muratore G; Goracci L; Mercorelli B; Foeglein Á; Digard P; Cruciani G; Palù G; Loregian A
Proc Natl Acad Sci U S A; 2012 Apr; 109(16):6247-52. PubMed ID: 22474359
[TBL] [Abstract][Full Text] [Related]
10. Identification of a small-molecule inhibitor of influenza virus via disrupting the subunits interaction of the viral polymerase.
Yuan S; Chu H; Zhao H; Zhang K; Singh K; Chow BK; Kao RY; Zhou J; Zheng BJ
Antiviral Res; 2016 Jan; 125():34-42. PubMed ID: 26593979
[TBL] [Abstract][Full Text] [Related]
11. Focusing on the Influenza Virus Polymerase Complex: Recent Progress in Drug Discovery and Assay Development.
Zhang J; Hu Y; Musharrafieh R; Yin H; Wang J
Curr Med Chem; 2019; 26(13):2243-2263. PubMed ID: 29984646
[TBL] [Abstract][Full Text] [Related]
12. Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors.
Jones JC; Kumar G; Barman S; Najera I; White SW; Webby RJ; Govorkova EA
mBio; 2018 Apr; 9(2):. PubMed ID: 29691337
[TBL] [Abstract][Full Text] [Related]
13. High-throughput docking for the identification of new influenza A virus polymerase inhibitors targeting the PA-PB1 protein-protein interaction.
Tintori C; Laurenzana I; Fallacara AL; Kessler U; Pilger B; Stergiou L; Botta M
Bioorg Med Chem Lett; 2014 Jan; 24(1):280-2. PubMed ID: 24314669
[TBL] [Abstract][Full Text] [Related]
14. Identification of a novel compound with antiviral activity against influenza A virus depending on PA subunit of viral RNA polymerase.
Yamada K; Koyama H; Hagiwara K; Ueda A; Sasaki Y; Kanesashi SN; Ueno R; Nakamura HK; Kuwata K; Shimizu K; Suzuki M; Aida Y
Microbes Infect; 2012 Aug; 14(9):740-7. PubMed ID: 22441116
[TBL] [Abstract][Full Text] [Related]
15. Structure-based discovery of anti-influenza virus A compounds among medicines.
Fukuoka M; Minakuchi M; Kawaguchi A; Nagata K; Kamatari YO; Kuwata K
Biochim Biophys Acta; 2012 Feb; 1820(2):90-5. PubMed ID: 22108550
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus.
He X; Zhou J; Bartlam M; Zhang R; Ma J; Lou Z; Li X; Li J; Joachimiak A; Zeng Z; Ge R; Rao Z; Liu Y
Nature; 2008 Aug; 454(7208):1123-6. PubMed ID: 18615018
[TBL] [Abstract][Full Text] [Related]
17. 4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling.
Trist IM; Nannetti G; Tintori C; Fallacara AL; Deodato D; Mercorelli B; Palù G; Wijtmans M; Gospodova T; Edink E; Verheij M; de Esch I; Viteva L; Loregian A; Botta M
J Med Chem; 2016 Mar; 59(6):2688-703. PubMed ID: 26924568
[TBL] [Abstract][Full Text] [Related]
18. Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity.
Desantis J; Nannetti G; Massari S; Barreca ML; Manfroni G; Cecchetti V; Palù G; Goracci L; Loregian A; Tabarrini O
Eur J Med Chem; 2017 Sep; 138():128-139. PubMed ID: 28666191
[TBL] [Abstract][Full Text] [Related]
19. Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral Attenuation.
Da Costa B; Sausset A; Munier S; Ghounaris A; Naffakh N; Le Goffic R; Delmas B
J Virol; 2015 Jun; 89(12):6376-90. PubMed ID: 25855727
[TBL] [Abstract][Full Text] [Related]
20. Identification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication.
Wunderlich K; Mayer D; Ranadheera C; Holler AS; Mänz B; Martin A; Chase G; Tegge W; Frank R; Kessler U; Schwemmle M
PLoS One; 2009 Oct; 4(10):e7517. PubMed ID: 19841738
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
