These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 28846075)

  • 21. Dissecting the p53-Mdm2 feedback loop in vivo: uncoupling the role in p53 stability and activity.
    Pant V; Lozano G
    Oncotarget; 2014 Mar; 5(5):1149-56. PubMed ID: 24658419
    [TBL] [Abstract][Full Text] [Related]  

  • 22. p53 ubiquitination: Mdm2 and beyond.
    Brooks CL; Gu W
    Mol Cell; 2006 Feb; 21(3):307-15. PubMed ID: 16455486
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Distinct downstream targets manifest p53-dependent pathologies in mice.
    Pant V; Xiong S; Chau G; Tsai K; Shetty G; Lozano G
    Oncogene; 2016 Nov; 35(44):5713-5721. PubMed ID: 27065327
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/p53 apoptotic signaling in cancer cells.
    Nardinocchi L; Puca R; Givol D; D'Orazi G
    FEBS Lett; 2010 Oct; 584(19):4253-8. PubMed ID: 20849851
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation.
    Lindström MS; Jin A; Deisenroth C; White Wolf G; Zhang Y
    Mol Cell Biol; 2007 Feb; 27(3):1056-68. PubMed ID: 17116689
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Chemotherapy induces NEDP1-mediated destabilization of MDM2.
    Watson IR; Li BK; Roche O; Blanch A; Ohh M; Irwin MS
    Oncogene; 2010 Jan; 29(2):297-304. PubMed ID: 19784069
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network.
    Toledo F; Krummel KA; Lee CJ; Liu CW; Rodewald LW; Tang M; Wahl GM
    Cancer Cell; 2006 Apr; 9(4):273-85. PubMed ID: 16616333
    [TBL] [Abstract][Full Text] [Related]  

  • 28. p53 mRNA and p53 Protein Structures Have Evolved Independently to Interact with MDM2.
    Karakostis K; Ponnuswamy A; Fusée LT; Bailly X; Laguerre L; Worall E; Vojtesek B; Nylander K; Fåhraeus R
    Mol Biol Evol; 2016 May; 33(5):1280-92. PubMed ID: 26823446
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Protein phosphatase 1 nuclear targeting subunit is a hypoxia inducible gene: its role in post-translational modification of p53 and MDM2.
    Lee SJ; Lim CJ; Min JK; Lee JK; Kim YM; Lee JY; Won MH; Kwon YG
    Cell Death Differ; 2007 Jun; 14(6):1106-16. PubMed ID: 17318220
    [TBL] [Abstract][Full Text] [Related]  

  • 30. HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response.
    Lim KH; Park JJ; Gu BH; Kim JO; Park SG; Baek KH
    Sci Rep; 2015 Aug; 5():12793. PubMed ID: 26238070
    [TBL] [Abstract][Full Text] [Related]  

  • 31. RNF12 promotes p53-dependent cell growth suppression and apoptosis by targeting MDM2 for destruction.
    Gao K; Wang C; Jin X; Xiao J; Zhang E; Yang X; Wang D; Huang H; Yu L; Zhang P
    Cancer Lett; 2016 May; 375(1):133-141. PubMed ID: 26926424
    [TBL] [Abstract][Full Text] [Related]  

  • 32. TRIAD1 is negatively regulated by the MDM2 E3 ligase.
    Bae S; Jung JH; An IS; Kim OY; Lee MJ; Lee JH; Park IC; Lee SJ; An S
    Oncol Rep; 2012 Nov; 28(5):1924-8. PubMed ID: 22940738
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells.
    Duan W; Gao L; Wu X; Zhang Y; Otterson GA; Villalona-Calero MA
    Exp Cell Res; 2006 Oct; 312(17):3370-8. PubMed ID: 16934800
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Tumor suppression and normal aging in mice with constitutively high p53 activity.
    Mendrysa SM; O'Leary KA; McElwee MK; Michalowski J; Eisenman RN; Powell DA; Perry ME
    Genes Dev; 2006 Jan; 20(1):16-21. PubMed ID: 16391230
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Critical role for Daxx in regulating Mdm2.
    Tang J; Qu LK; Zhang J; Wang W; Michaelson JS; Degenhardt YY; El-Deiry WS; Yang X
    Nat Cell Biol; 2006 Aug; 8(8):855-62. PubMed ID: 16845383
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Indispensable role of Mdm2/p53 interaction during the embryonic and postnatal inner ear development.
    Laos M; Sulg M; Herranen A; Anttonen T; Pirvola U
    Sci Rep; 2017 Feb; 7():42216. PubMed ID: 28181574
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Functions of the MDM2 oncoprotein.
    Freedman DA; Wu L; Levine AJ
    Cell Mol Life Sci; 1999 Jan; 55(1):96-107. PubMed ID: 10065155
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells.
    Wu W; Xu C; Ling X; Fan C; Buckley BP; Chernov MV; Ellis L; Li F; Muñoz IG; Wang X
    Cell Death Dis; 2015 Dec; 6(12):e2035. PubMed ID: 26720344
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cardiac-specific ablation of the E3 ubiquitin ligase Mdm2 leads to oxidative stress, broad mitochondrial deficiency and early death.
    Hauck L; Stanley-Hasnain S; Fung A; Grothe D; Rao V; Mak TW; Billia F
    PLoS One; 2017; 12(12):e0189861. PubMed ID: 29267372
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Alterations of the Mdm2 C-Terminus Differentially Impact Its Function In Vivo.
    Pant V; Aryal NK; Xiong S; Chau GP; Fowlkes NW; Lozano G
    Cancer Res; 2022 Apr; 82(7):1313-1320. PubMed ID: 35078816
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.