BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

439 related articles for article (PubMed ID: 28848049)

  • 1. Hypoxia-inducible factor 2α (HIF-2α) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity.
    Ma X; Zhang H; Xue X; Shah YM
    J Biol Chem; 2017 Oct; 292(41):17046-17056. PubMed ID: 28848049
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Epithelial Hypoxia-Inducible Factor 2α Facilitates the Progression of Colon Tumors through Recruiting Neutrophils.
    Triner D; Xue X; Schwartz AJ; Jung I; Colacino JA; Shah YM
    Mol Cell Biol; 2017 Mar; 37(5):. PubMed ID: 27956697
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance.
    Zhou D; Zhang Y; Wu H; Barry E; Yin Y; Lawrence E; Dawson D; Willis JE; Markowitz SD; Camargo FD; Avruch J
    Proc Natl Acad Sci U S A; 2011 Dec; 108(49):E1312-20. PubMed ID: 22042863
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oncogenic KRAS and BRAF differentially regulate hypoxia-inducible factor-1alpha and -2alpha in colon cancer.
    Kikuchi H; Pino MS; Zeng M; Shirasawa S; Chung DC
    Cancer Res; 2009 Nov; 69(21):8499-506. PubMed ID: 19843849
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disruption of hypoxia-inducible factor-2α in neutrophils decreases colitis-associated colon cancer.
    Singhal R; Kotla NK; Solanki S; Huang W; Bell HN; El-Derany MO; Castillo C; Shah YM
    Am J Physiol Gastrointest Liver Physiol; 2024 Jan; 326(1):G53-G66. PubMed ID: 37933447
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxia-inducible factor-2α directly promotes BCRP expression and mediates the resistance of ovarian cancer stem cells to adriamycin.
    He M; Wu H; Jiang Q; Liu Y; Han L; Yan Y; Wei B; Liu F; Deng X; Chen H; Zhao L; Wang M; Wu X; Yao W; Zhao H; Chen J; Wei M
    Mol Oncol; 2019 Feb; 13(2):403-421. PubMed ID: 30536571
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alternate RASSF1 Transcripts Control SRC Activity, E-Cadherin Contacts, and YAP-Mediated Invasion.
    Vlahov N; Scrace S; Soto MS; Grawenda AM; Bradley L; Pankova D; Papaspyropoulos A; Yee KS; Buffa F; Goding CR; Timpson P; Sibson N; O'Neill E
    Curr Biol; 2015 Dec; 25(23):3019-34. PubMed ID: 26549256
    [TBL] [Abstract][Full Text] [Related]  

  • 8. c-Myc is regulated by HIF-2α in chronic hypoxia and influences sensitivity to 5-FU in colon cancer.
    Wang L; Xue M; Chung DC
    Oncotarget; 2016 Nov; 7(48):78910-78917. PubMed ID: 27793037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prostaglandin E
    Kim HB; Kim M; Park YS; Park I; Kim T; Yang SY; Cho CJ; Hwang D; Jung JH; Markowitz SD; Hwang SW; Yang SK; Lim DS; Myung SJ
    Gastroenterology; 2017 Feb; 152(3):616-630. PubMed ID: 27864128
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HIF-3α1 promotes colorectal tumor cell growth by activation of JAK-STAT3 signaling.
    Xue X; Jungles K; Onder G; Samhoun J; Győrffy B; Hardiman KM
    Oncotarget; 2016 Mar; 7(10):11567-79. PubMed ID: 26871465
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypoxia-inducible factors modulate the stemness and malignancy of colon cancer cells by playing opposite roles in canonical Wnt signaling.
    Santoyo-Ramos P; Likhatcheva M; García-Zepeda EA; Castañeda-Patlán MC; Robles-Flores M
    PLoS One; 2014; 9(11):e112580. PubMed ID: 25396735
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron.
    Singhal R; Mitta SR; Das NK; Kerk SA; Sajjakulnukit P; Solanki S; Andren A; Kumar R; Olive KP; Banerjee R; Lyssiotis CA; Shah YM
    J Clin Invest; 2021 Jun; 131(12):. PubMed ID: 33914705
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Upregulation of HIF-2α induced by sorafenib contributes to the resistance by activating the TGF-α/EGFR pathway in hepatocellular carcinoma cells.
    Zhao D; Zhai B; He C; Tan G; Jiang X; Pan S; Dong X; Wei Z; Ma L; Qiao H; Jiang H; Sun X
    Cell Signal; 2014 May; 26(5):1030-9. PubMed ID: 24486412
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HIF-2α promotes conversion to a stem cell phenotype and induces chemoresistance in breast cancer cells by activating Wnt and Notch pathways.
    Yan Y; Liu F; Han L; Zhao L; Chen J; Olopade OI; He M; Wei M
    J Exp Clin Cancer Res; 2018 Oct; 37(1):256. PubMed ID: 30340507
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoxia-inducible factor-2α promotes fibrosis in non-alcoholic fatty liver disease by enhancing glutamine catabolism and inhibiting yes-associated protein phosphorylation in hepatic stellate cells.
    Yan R; Cai H; Zhou X; Bao G; Bai Z; Ge RL
    Front Endocrinol (Lausanne); 2024; 15():1344971. PubMed ID: 38501098
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha.
    Park SK; Dadak AM; Haase VH; Fontana L; Giaccia AJ; Johnson RS
    Mol Cell Biol; 2003 Jul; 23(14):4959-71. PubMed ID: 12832481
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis.
    Greenhough A; Bagley C; Heesom KJ; Gurevich DB; Gay D; Bond M; Collard TJ; Paraskeva C; Martin P; Sansom OJ; Malik K; Williams AC
    EMBO Mol Med; 2018 Nov; 10(11):. PubMed ID: 30143543
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress.
    Zhang X; Li Y; Ma Y; Yang L; Wang T; Meng X; Zong Z; Sun X; Hua X; Li H
    J Exp Clin Cancer Res; 2018 Sep; 37(1):216. PubMed ID: 30180863
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1.
    Zhang H; Ramakrishnan SK; Triner D; Centofanti B; Maitra D; Győrffy B; Sebolt-Leopold JS; Dame MK; Varani J; Brenner DE; Fearon ER; Omary MB; Shah YM
    Sci Signal; 2015 Oct; 8(397):ra98. PubMed ID: 26443705
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BHLHA15-Positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice.
    Hayakawa Y; Tsuboi M; Asfaha S; Kinoshita H; Niikura R; Konishi M; Hata M; Oya Y; Kim W; Middelhoff M; Hikiba Y; Higashijima N; Ihara S; Ushiku T; Fukayama M; Tailor Y; Hirata Y; Guha C; Yan KS; Koike K; Wang TC
    Gastroenterology; 2019 Mar; 156(4):1066-1081.e16. PubMed ID: 30448068
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.