BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 28848088)

  • 1. The SGK1 Kinase Inhibitor SI113 Sensitizes Theranostic Effects of the 64CuCl2 in Human Glioblastoma Multiforme Cells.
    Catalogna G; Talarico C; Dattilo V; Gangemi V; Calabria F; D'Antona L; Schenone S; Musumeci F; Bianco C; Perrotti N; Amato R; Cascini GL
    Cell Physiol Biochem; 2017; 43(1):108-119. PubMed ID: 28848088
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells.
    Talarico C; Dattilo V; D'Antona L; Barone A; Amodio N; Belviso S; Musumeci F; Abbruzzese C; Bianco C; Trapasso F; Schenone S; Alcaro S; Ortuso F; Florio T; Paggi MG; Perrotti N; Amato R
    Oncotarget; 2016 Mar; 7(13):15868-84. PubMed ID: 26908461
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy.
    Talarico C; D'Antona L; Scumaci D; Barone A; Gigliotti F; Fiumara CV; Dattilo V; Gallo E; Visca P; Ortuso F; Abbruzzese C; Botta L; Schenone S; Cuda G; Alcaro S; Bianco C; Lavia P; Paggi MG; Perrotti N; Amato R
    Oncotarget; 2015 Nov; 6(35):37511-25. PubMed ID: 26462020
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation.
    D'Antona L; Amato R; Talarico C; Ortuso F; Menniti M; Dattilo V; Iuliano R; Gigliotti F; Artese A; Costa G; Schenone S; Musumeci F; Abbruzzese C; Botta L; Trapasso F; Alcaro S; Paggi MG; Perrotti N
    Cell Physiol Biochem; 2015; 35(5):2006-18. PubMed ID: 25871776
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells.
    Conza D; Mirra P; Calì G; Tortora T; Insabato L; Fiory F; Schenone S; Amato R; Beguinot F; Perrotti N; Ulianich L
    J Cell Physiol; 2017 Dec; 232(12):3735-3743. PubMed ID: 28177128
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells.
    Matteoni S; Abbruzzese C; Matarrese P; De Luca G; Mileo AM; Miccadei S; Schenone S; Musumeci F; Haas TL; Sette G; Carapella CM; Amato R; Perrotti N; Signore M; Paggi MG
    J Exp Clin Cancer Res; 2019 May; 38(1):202. PubMed ID: 31101126
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Blockade of TGF-β signaling by the TGFβR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma.
    Zhang M; Kleber S; Röhrich M; Timke C; Han N; Tuettenberg J; Martin-Villalba A; Debus J; Peschke P; Wirkner U; Lahn M; Huber PE
    Cancer Res; 2011 Dec; 71(23):7155-67. PubMed ID: 22006998
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme.
    Abbruzzese C; Catalogna G; Gallo E; di Martino S; Mileo AM; Carosi M; Dattilo V; Schenone S; Musumeci F; Lavia P; Perrotti N; Amato R; Paggi MG
    Oncotarget; 2017 Dec; 8(67):110743-110755. PubMed ID: 29340013
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TBK1 Inhibitor Exerts Antiproliferative Effect on Glioblastoma Multiforme Cells.
    Scuderi SA; Lanza M; Casili G; Esposito F; Colarossi C; Giuffrida D; Irene P; Cuzzocrea S; Esposito E; Campolo M
    Oncol Res; 2021 Sep; 28(7):779-790. PubMed ID: 33741083
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells.
    Daniele S; Costa B; Zappelli E; Da Pozzo E; Sestito S; Nesi G; Campiglia P; Marinelli L; Novellino E; Rapposelli S; Martini C
    Sci Rep; 2015 Apr; 5():9956. PubMed ID: 25898313
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy.
    Ströbele S; Schneider M; Schneele L; Siegelin MD; Nonnenmacher L; Zhou S; Karpel-Massler G; Westhoff MA; Halatsch ME; Debatin KM
    PLoS One; 2015; 10(6):e0131670. PubMed ID: 26121251
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The small molecule SI113 hinders epithelial-to-mesenchymal transition and subverts cytoskeletal organization in human cancer cells.
    Abbruzzese C; Matteoni S; Persico M; Ascione B; Schenone S; Musumeci F; Amato R; Perrotti N; Matarrese P; Paggi MG
    J Cell Physiol; 2019 Dec; 234(12):22529-22542. PubMed ID: 31099037
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma.
    Rango E; D'Antona L; Iovenitti G; Brai A; Mancini A; Zamperini C; Trivisani CI; Marianelli S; Fallacara AL; Molinari A; Cianciusi A; Schenone S; Perrotti N; Dreassi E; Botta M
    Eur J Med Chem; 2021 Nov; 223():113653. PubMed ID: 34161866
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Large-Scale RNAi Screen Identifies SGK1 as a Key Survival Kinase for GBM Stem Cells.
    Kulkarni S; Goel-Bhattacharya S; Sengupta S; Cochran BH
    Mol Cancer Res; 2018 Jan; 16(1):103-114. PubMed ID: 28993509
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glioblastoma Multiforme: Fewer Tumor Copy Number Segments of the
    Lehrer S; Rheinstein PH; Rosenzweig KE
    Cancer Genomics Proteomics; 2018; 15(4):273-278. PubMed ID: 29976632
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SGK1 inhibits cellular apoptosis and promotes proliferation via the MEK/ERK/p53 pathway in colitis.
    Bai JA; Xu GF; Yan LJ; Zeng WW; Ji QQ; Wu JD; Tang QY
    World J Gastroenterol; 2015 May; 21(20):6180-93. PubMed ID: 26034353
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular response of human glioblastoma multiforme cells to ionizing radiation: cell cycle arrest, modulation of the expression of cyclin-dependent kinase inhibitors, and autophagy.
    Yao KC; Komata T; Kondo Y; Kanzawa T; Kondo S; Germano IM
    J Neurosurg; 2003 Feb; 98(2):378-84. PubMed ID: 12593626
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ATM protein expression correlates with radioresistance in primary glioblastoma cells in culture.
    Tribius S; Pidel A; Casper D
    Int J Radiat Oncol Biol Phys; 2001 Jun; 50(2):511-23. PubMed ID: 11380241
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FoxO proteins or loss of functional p53 maintain stemness of glioblastoma stem cells and survival after ionizing radiation plus PI3K/mTOR inhibition.
    Firat E; Niedermann G
    Oncotarget; 2016 Aug; 7(34):54883-54896. PubMed ID: 27448972
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment.
    Tanaka K; Sasayama T; Irino Y; Takata K; Nagashima H; Satoh N; Kyotani K; Mizowaki T; Imahori T; Ejima Y; Masui K; Gini B; Yang H; Hosoda K; Sasaki R; Mischel PS; Kohmura E
    J Clin Invest; 2015 Apr; 125(4):1591-602. PubMed ID: 25798620
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.