BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 28851842)

  • 1. A chemical compound inhibiting the Aha1-Hsp90 chaperone complex.
    Stiegler SC; Rübbelke M; Korotkov VS; Weiwad M; John C; Fischer G; Sieber SA; Sattler M; Buchner J
    J Biol Chem; 2017 Oct; 292(41):17073-17083. PubMed ID: 28851842
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hsp90 cochaperone Aha1 is a negative regulator of the Saccharomyces MAL activator and acts early in the chaperone activation pathway.
    Ran F; Gadura N; Michels CA
    J Biol Chem; 2010 Apr; 285(18):13850-62. PubMed ID: 20177068
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery.
    Meyer P; Prodromou C; Liao C; Hu B; Roe SM; Vaughan CK; Vlasic I; Panaretou B; Piper PW; Pearl LH
    EMBO J; 2004 Mar; 23(6):1402-10. PubMed ID: 15039704
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Asymmetric activation of the hsp90 dimer by its cochaperone aha1.
    Retzlaff M; Hagn F; Mitschke L; Hessling M; Gugel F; Kessler H; Richter K; Buchner J
    Mol Cell; 2010 Feb; 37(3):344-54. PubMed ID: 20159554
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle.
    Li J; Richter K; Reinstein J; Buchner J
    Nat Struct Mol Biol; 2013 Mar; 20(3):326-31. PubMed ID: 23396352
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle.
    Siligardi G; Hu B; Panaretou B; Piper PW; Pearl LH; Prodromou C
    J Biol Chem; 2004 Dec; 279(50):51989-98. PubMed ID: 15466438
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel C-terminal homologue of Aha1 co-chaperone binds to heat shock protein 90 and stimulates its ATPase activity in Entamoeba histolytica.
    Singh M; Shah V; Tatu U
    J Mol Biol; 2014 Apr; 426(8):1786-98. PubMed ID: 24486610
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation.
    Mercier R; Wolmarans A; Schubert J; Neuweiler H; Johnson JL; LaPointe P
    Nat Commun; 2019 Mar; 10(1):1273. PubMed ID: 30894538
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone.
    Lotz GP; Lin H; Harst A; Obermann WM
    J Biol Chem; 2003 May; 278(19):17228-35. PubMed ID: 12604615
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery.
    Meyer P; Prodromou C; Liao C; Hu B; Mark Roe S; Vaughan CK; Vlasic I; Panaretou B; Piper PW; Pearl LH
    EMBO J; 2004 Feb; 23(3):511-9. PubMed ID: 14739935
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of celastrol to inhibit hsp90 and cdc37 interaction.
    Zhang T; Li Y; Yu Y; Zou P; Jiang Y; Sun D
    J Biol Chem; 2009 Dec; 284(51):35381-9. PubMed ID: 19858214
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p23 and Aha1: Distinct Functions Promote Client Maturation.
    Biebl MM; Buchner J
    Subcell Biochem; 2023; 101():159-187. PubMed ID: 36520307
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Mechanism of Hsp90 ATPase Stimulation by Aha1.
    Wolmarans A; Lee B; Spyracopoulos L; LaPointe P
    Sci Rep; 2016 Sep; 6():33179. PubMed ID: 27615124
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The co-chaperone Hch1 regulates Hsp90 function differently than its homologue Aha1 and confers sensitivity to yeast to the Hsp90 inhibitor NVP-AUY922.
    Armstrong H; Wolmarans A; Mercier R; Mai B; LaPointe P
    PLoS One; 2012; 7(11):e49322. PubMed ID: 23166640
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cdc37 (cell division cycle 37) restricts Hsp90 (heat shock protein 90) motility by interaction with N-terminal and middle domain binding sites.
    Eckl JM; Rutz DA; Haslbeck V; Zierer BK; Reinstein J; Richter K
    J Biol Chem; 2013 May; 288(22):16032-42. PubMed ID: 23569206
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aha1 competes with Hop, p50 and p23 for binding to the molecular chaperone Hsp90 and contributes to kinase and hormone receptor activation.
    Harst A; Lin H; Obermann WM
    Biochem J; 2005 May; 387(Pt 3):789-96. PubMed ID: 15584899
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Detection of the ATPase activity of the molecular chaperones Hsp90 and Hsp72 using the TranscreenerTM ADP assay kit.
    Rowlands M; McAndrew C; Prodromou C; Pearl L; Kalusa A; Jones K; Workman P; Aherne W
    J Biomol Screen; 2010 Mar; 15(3):279-86. PubMed ID: 20147598
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity.
    Mollapour M; Tsutsumi S; Truman AW; Xu W; Vaughan CK; Beebe K; Konstantinova A; Vourganti S; Panaretou B; Piper PW; Trepel JB; Prodromou C; Pearl LH; Neckers L
    Mol Cell; 2011 Mar; 41(6):672-81. PubMed ID: 21419342
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1.
    Panaretou B; Siligardi G; Meyer P; Maloney A; Sullivan JK; Singh S; Millson SH; Clarke PA; Naaby-Hansen S; Stein R; Cramer R; Mollapour M; Workman P; Piper PW; Pearl LH; Prodromou C
    Mol Cell; 2002 Dec; 10(6):1307-18. PubMed ID: 12504007
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dynamic Aha1 co-chaperone binding to human Hsp90.
    Oroz J; Blair LJ; Zweckstetter M
    Protein Sci; 2019 Sep; 28(9):1545-1551. PubMed ID: 31299134
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.